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Improving the outcome of treating striae gravidarum by combined therapies using topical β-glucan and 1565-nm non-ablative fractional laser: A prospective randomized vehicle-controlled parallel group study
J Dermatol. 2022 May 15. doi: 10.1111/1346-8138.16417. Online ahead of print.ABSTRACTStriae gravidarum (SG) is a kind of dermal scar associated with psychosocial and therapeutic challenge. Topical reagents and non-invasive laser are more preferred than invasive procedures for less pain and shorter downtime. However, there are few studies on comparing and combining these two modalities. The aim of the present study was to evaluate the efficacy and tolerance of a topical regimen containing β-glucan, 1565-nm non-ablative fractional laser (NAFL; ResurFX), and combination of them for SG. A total of 128 unilateral abdomens from...
Source: Pain Physician - May 16, 2022 Category: Anesthesiology Authors: Yajing Cao Peiru Wang Xiaojing Liu Guolong Zhang Zhi Cao Huan Xue Qiumin He Xiuli Wang Source Type: research

Correction to: Observation on the efficacy of 1565 ‑nm non‑ablative fractional laser combined with compound betamethasone topical application on the treatment of early scar in Chinese patients
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - May 7, 2022 Category: Laser Surgery Source Type: research

Observation on the efficacy of 1565-nm non-ablative fractional laser combined with compound betamethasone topical application on the treatment of early scar in Chinese patients
The objective of the study was to evaluate the efficacy of combining 1565-nm non-ablative fractional laser with low-dose compound betamethasone topical application in the treatment of immature early red hypertrophic scar. We enrolled 38 cases of patients who had immature red hypertrophic scar due to surgery or trauma which are all less than 6 months old. About 28 patients were assigned to the treatment group, and 10 patients were assigned to the control group. The patients in the treatment group were all treated with 1565-nm non-ablative fractional laser with the following parameters: spot size 10–16 mm, round or squa...
Source: Lasers in Medical Science - April 28, 2022 Category: Laser Surgery Source Type: research

Fluocinolone Acetonide Microemulsion in Combination with a Fractional Laser for the Treatment of Scalp Psoriasis
This study introduces fluocinolone acetonide (FA) microemulsion in combination with ablative fractional lasering as a new effective treatment for scalp psoriasis. A pseudo-ternary phase diagram was constructed using the aqueous titration method. The suitable ratio of surfactant mixture (Smix):oil mixture (Omix):water was chosen from the microemulsion region of the diagram. FA was loaded into the selected ratio to prepare FA microemulsion. Ex vivo skin permeation study of the FA microemulsion with fractional laser assistance was performed to determine a proper ablative depth. A pilot clinical study was conducted to evaluate...
Source: AAPS PharmSciTech - April 23, 2022 Category: Drugs & Pharmacology Authors: Voraphol Vejjabhinanta Walaisiri Muangsiri Pornpen Werawatganone Source Type: research