Cancers, Vol. 14, Pages 5463: Enhanced Recovery after Uterine Corpus Cancer Surgery: A 10 Year Retrospective Cohort Study of Robotic Surgery in an NHS Cancer Centre
Simon Butler-Manuel Royal Surrey NHS Foundation Trust introduced robotic surgery for uterine corpus cancer in 2010 to support increased access to minimally invasive surgery, a central element of an enhanced recovery after surgery (ERAS) pathway. More than 1750 gynaecological oncology robotic procedures have now been performed at Royal Surrey NHS Foundation Trust. A retrospective cohort study was performed of patients undergoing surgery for uterine corpus cancer between the 1 January 2010 and the 31 December 2019 to evaluate its success. Data was extracted from the dedicated gynaecological oncology database and a detail...
Source: Cancers - November 7, 2022 Category: Cancer & Oncology Authors: Christina Uwins Radwa Hablase Hasanthi Assalaarachchi Anil Tailor Alexandra Stewart Jayanta Chatterjee Patricia Ellis Simon S. Skene Agnieszka Michael Simon Butler-Manuel Tags: Article Source Type: research

Corrigendum to “Prospective study of the association between depressive symptoms at type 2 diabetes diagnosis and time to insulin initiation in the South London diabetes (SOUL-D) cohort” [Prim. Care Diabetes 16 (2022) 502–508]
The authors regret that an error occurred in the acknowledgment section of the original paper. This research was part-funded by the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King ’s College London. (Source: Primary Care Diabetes)
Source: Primary Care Diabetes - November 5, 2022 Category: Primary Care Authors: Rebecca Upsher, Dulce Alarc ón-Yaquetto, Daniel Stahl, Khalida Ismail, Kirsty Winkley Tags: Corrigendum Source Type: research

Physical activity, sedentary behaviour and well-being: experiences of people with knee and hip osteoarthritis
. (Source: Psychology and Health)
Source: Psychology and Health - October 3, 2022 Category: Psychiatry & Psychology Authors: Archontissa M. KanavakiAlison RushtonElizabeth HaleRainer KlockeAbhishek AbhishekJoan L. Dudaa School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UKb Department of Rheumatology, Dudley Group NHS Foundation Trust, Source Type: research

Ethics briefing
The Tavistock and Portman NHS Foundation Trust - Cass Review and potential further legal action In previous Ethics briefings1 we have highlighted the developments in the case of Bell & Another v the Tavistock and Portman NHS Foundation Trust. The case concerned a judicial review of the practice of prescribing puberty blocking treatment to children and young people at the Gender Identity Development Service (GIDS) managed by the Tavistock and Portman NHS Foundation Trust (the Trust). The Court of Appeal in its judgement2 found the Trust’s practices to be lawful, and overturned previous guidance given by the High C...
Source: Journal of Medical Ethics - September 28, 2022 Category: Medical Ethics Authors: Mussell, R., Brannan, S., Harrison, C. A., Sheather, J. C., English, V. Tags: Ethics briefing Source Type: research

Evaluating social drop-in facilities and their impact on social recovery in early intervention in psychosis services
Jessica Lee, Donna Haskayne, Madihah Hussain, Abbas Darukhanawala, Charlotte Marriott Mental Health Review Journal, Vol. ahead-of-print, No. ahead-of-print, pp.- “Social recovery” is a long-cited aim within the UK early intervention in psychosis (EIP) services; however, there is a lack of evidence regarding existing social recovery provisions and how these can be improved. This paper aims to evaluate an existing social drop-in facility within an EIP team, ran within the Birmingham and Solihull Mental Health NHS Foundation Trust, and highlight the potential benefits of delivering such servic...
Source: Mental Health Review Journal - September 23, 2022 Category: Psychiatry Authors: Jessica Lee Donna Haskayne Madihah Hussain Abbas Darukhanawala Charlotte Marriott Source Type: research

Protocol for an observational study investigating hormones triggering the onset of sustained lactation: the INSIGHT study
Introduction Lactation is a hormonally controlled process that promotes infant growth and neurodevelopment and reduces the long-term maternal risk of diabetes, cardiovascular disease and breast cancer. Hormones, such as prolactin and progesterone, mediate mammary development during pregnancy and are critical for initiating copious milk secretion within 24–72 hours post partum. However, the hormone concentrations mediating lactation onset are ill defined. Methods and analysis The primary objective of the investigating hormones triggering the onset of sustained lactation study is to establish reference intervals for t...
Source: BMJ Open - August 30, 2022 Category: General Medicine Authors: Rostom, H., Meng, X., Price, H., Fry, A., Elajnaf, T., Humphrey, R., Guha, N., James, T., Kennedy, S. H., Hannan, F. M. Tags: Open access, Diabetes and Endocrinology Source Type: research

Obsessive –compulsive disorder in treatment seeking children & amp; adolescents during the COVID-19 pandemic
This study aims to investigate whether the pandemic is associated with increased referral of young people with OCD, any changes in their symptom severity and treatment offered.MethodsService data were used to investigate 58 young people (8 –17 years) referred and assessed in the Central and Northwest London NHS Foundation Trust Child and Adolescent Mental Health Service (CAMHS), before and during the COVID-19 pandemic (months March-October 2018–2020). Changes in symptom severity were measured using the Health of the Nation Outcom e Scale for Children and Adolescents (HoNOSCA). Patient records were reviewed to assess i...
Source: European Child and Adolescent Psychiatry - August 30, 2022 Category: Psychiatry Source Type: research

Correction: Understanding stage of innovation of invasive procedures and devices: protocol for a systematic review and thematic analysis
This study was supported by the Medical Research Council [MR/S001751/1] and NIHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol. (Source: BMJ Open)
Source: BMJ Open - August 26, 2022 Category: General Medicine Tags: Open access Correction Source Type: research

Prospective study of pediatric patients presenting with idiopathic infantile nystagmus —Management and molecular diagnostics
This study expands the mutational spectrum of IIN and highlights the significant role of an integrated care pathway and broader panel testing in excluding underlying pathologies. (Source: Frontiers in Genetics)
Source: Frontiers in Genetics - August 22, 2022 Category: Genetics & Stem Cells Source Type: research

Service user experiences of mental health assessments: a systematic review and thematic synthesis of qualitative literature
. (Source: Journal of Mental Health)
Source: Journal of Mental Health - August 13, 2022 Category: Psychiatry Authors: Paras PatelAngela KennedySarah CarrSteve GillardPoppy HarrisAngela Sweeneya Cumbria, Northumberland and Tyne and Wear NHS Foundation Trust, Newcastle, UKb Service User Research Enterprise, Institute of Psychiatry, Psychology and Neuroscience, King ’s Co Source Type: research

020 The headache hub: a multidisciplinary diagnosis and management resource for GPs
The need to improve care of patients with headache prompted development of a new model in South West London. The Headache Hub, piloted at St George’s University Hospitals NHS Foundation Trust, consisted of a multidisciplinary team; Consultant Neurologists, GP with Extended Role and Allied Health Professionals. The Hub triages new GP referrals and offers an online migraine group clinic (engaging patients through shared medical appointments in a group setting). Between April-December 2021, 171 GP referred patients were seen, of which 96 (48%) had Chronic Migraine (CM), 36 (18%) High Frequency Episodic Migraine and 23 (...
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 12, 2022 Category: Neurosurgery Authors: Logan, A.-M., Lee, N., Patel, B., Dolling, R., Pink, K., Nitkunan, A., Mansour, N., Khan, U., Wilkinson, T., Nirmalananthan, N. Tags: Poster presentations Source Type: research

Human Papillomavirus-Associated Combined Neuroendocrine and Squamous Cell Carcinoma of the Sinonasal Tract
We describe a case of HPV-associated combined neuroendocrine and SCC of the sinonasal tract. Recognition of HPV association with this entity avoids diagnostic pitfalls. (Source: Head and Neck Pathology)
Source: Head and Neck Pathology - August 3, 2022 Category: Pathology Source Type: research

A Machine Learning Solution to Predict Elective Orthopedic Surgery Case Duration
Stud Health Technol Inform. 2022 Jun 29;295:559-561. doi: 10.3233/SHTI220789.ABSTRACTWe used surgery durations, patient demographic and personnel data taken from the East Kent Hospitals University NHS Foundation Trust (EKHUFT) over a period of 10 years (2010-2019) for a total of 25,352 patients that underwent 15 highest volume elective orthopedic surgeries, to predict future surgery durations for the subset of elective surgeries under consideration. As part of this study, we compared two different ensemble machine learning methods random forest regression (RF) and XGBoost (eXtreme Gradient Boosting) regression. The two mod...
Source: Studies in Health Technology and Informatics - July 1, 2022 Category: Information Technology Authors: Divya Sahadev Thomas Lovegrove Holger Kunz Source Type: research

Phenotyping of idiopathic pulmonary arterial hypertension: a registry analysis
Lancet Respir Med. 2022 Jun 28:S2213-2600(22)00097-2. doi: 10.1016/S2213-2600(22)00097-2. Online ahead of print.ABSTRACTBACKGROUND: Among patients meeting diagnostic criteria for idiopathic pulmonary arterial hypertension (IPAH), there is an emerging lung phenotype characterised by a low diffusion capacity for carbon monoxide (DLCO) and a smoking history. The present study aimed at a detailed characterisation of these patients.METHODS: We analysed data from two European pulmonary hypertension registries, COMPERA (launched in 2007) and ASPIRE (from 2001 onwards), to identify patients diagnosed with IPAH and a lung phenotype...
Source: Respiratory Care - July 1, 2022 Category: Respiratory Medicine Authors: Marius M Hoeper Krit Dwivedi Christine Pausch Robert A Lewis Karen M Olsson Doerte Huscher David Pittrow Ekkehard Gr ünig Gerd Staehler Carmine Dario Vizza Henning Gall Oliver Distler Christian Opitz John Simon R Gibbs Marion Delcroix Da-Hee Park Hossein Source Type: research