Evaluation of safety of fluoxetine for cerebellar mutism syndrome in children after posterior fossa surgery
CONCLUSION: This study suggests a positive safety profile of fluoxetine used in postoperative CMS. It does not answer the question of whether the treatment is effective for this indication. A randomized controlled trial based on a syndrome severity scale should be conducted to provide a more reliable assessment of the efficacy and safety of fluoxetine.PMID:38485568 | DOI:10.1016/j.arcped.2023.10.010 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 14, 2024 Category: Pediatrics Authors: Roxane Varengue Matthieu Delion Emilie De Carli Luc Le Fournier Julien Durigneux Mickael Dinomais Patrick Van Bogaert Source Type: research
Current Understanding of Compulsive Sexual Behavior Disorder and Co-occurring Conditions: What Clinicians Should Know about Pharmacological Options
AbstractCompulsive sexual behavior disorder (CSBD) has recently been recognized as a psychiatric disorder. Pharmacological treatments for CSBD have received little study and thus have limited empirical support. The main objective of the present work is to review existing literature on the efficacy of different drugs on the symptomatology of CSBD, including the subtype of problematic pornography use (PPU). The main pharmacological approaches to treating CSBD have included opioid antagonists (naltrexone and nalmefene), selective serotonin reuptake inhibitors (paroxetine, citalopram, fluoxetine, and sertraline), mood stabiliz...
Source: CNS Drugs - March 14, 2024 Category: Neurology Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Psychoactive substance consumption after the Fund ão dam mine tailing disaster in Minas Gerais State, Brazil
Cad Saude Publica. 2024 Mar 11;40(3):e00237022. doi: 10.1590/0102-311XEN237022. eCollection 2024.ABSTRACTDisasters cause changes in morbidity, mortality, and medicine use. Brazil is one of the main producers of mineral ores at great environmental cost. Mine tailings are stored in dams and ruptures have led to major disasters. We investigated the consumption of psychoactive medicines in the municipalities affected by the Fundão dam disaster in Minas Gerais State. An ecological study was carried out on drug consumption, estimated using public purchases in Minas Gerais and dispensing data from private retail pharmacies. Cons...
Source: Cadernos de Saude Publica - March 13, 2024 Category: International Medicine & Public Health Authors: Elaine Silva Miranda Marcelo Dell'Aringa Everaldo Alves da Costa Thais Piazza Francesco Della Corte Luca Ragazzoni Francesco Barone-Adesi Carla Louren ço Tavares de Andrade Claudia Garcia Serpa Osorio-de-Castro Source Type: research
Elucidation of escitalopram oxalate and related antidepressants as putative inhibitors of PTP4A3/PRL-3 protein in hepatocellular carcinoma: A multi-computational investigation
Comput Biol Chem. 2024 Feb 29;110:108039. doi: 10.1016/j.compbiolchem.2024.108039. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) persists to be one of the most devastating and deadliest malignancies globally. Recent research into the molecular signaling networks entailed in many malignancies has given some prominent insights that can be leveraged to create molecular therapeutics for combating HCC. Therefore, in the current communication, an in-silico drug repurposing approach has been employed to target the function of PTP4A3/PRL-3 protein in HCC using antidepressants: Fluoxetine hydrochloride, Citalopram, A...
Source: Computational Biology and Chemistry - March 12, 2024 Category: Bioinformatics Authors: Ishfaq Hassan Mir Kankipati Teja Shyam Susmida Seni Balakrishnan Muthuvel Suresh Kumar Thiyagarajan Ramesh Chinnasamy Thirunavukkarasu Source Type: research
Elucidation of escitalopram oxalate and related antidepressants as putative inhibitors of PTP4A3/PRL-3 protein in hepatocellular carcinoma: A multi-computational investigation
Comput Biol Chem. 2024 Feb 29;110:108039. doi: 10.1016/j.compbiolchem.2024.108039. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) persists to be one of the most devastating and deadliest malignancies globally. Recent research into the molecular signaling networks entailed in many malignancies has given some prominent insights that can be leveraged to create molecular therapeutics for combating HCC. Therefore, in the current communication, an in-silico drug repurposing approach has been employed to target the function of PTP4A3/PRL-3 protein in HCC using antidepressants: Fluoxetine hydrochloride, Citalopram, A...
Source: Computational Biology and Chemistry - March 12, 2024 Category: Bioinformatics Authors: Ishfaq Hassan Mir Kankipati Teja Shyam Susmida Seni Balakrishnan Muthuvel Suresh Kumar Thiyagarajan Ramesh Chinnasamy Thirunavukkarasu Source Type: research
