Efficacy of Fluocinonide\Bifonazole cream for the treatment of trachyonychia: A retrospective case series
Conclusion: Occluded application of fluocinonide plus bifonazole cream is efficient for the treatment of trachyonychia and should be considered a first line of treatment. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - February 23, 2023 Category: Dermatology Authors: Avner Shemer Ralph Daniel Riad Kassem Nechama Sharon Renata Farhi Baruch Kaplan Vered Hermush Eran Galili Source Type: research

676 Variation in Medicare topical steroid prescription costs
Rising costs of topical steroids (TS) have doubled out-of-pocket costs for seniors from 2011-2015. Still, variation within and between different drug potencies and regions is unknown. Herein, we analyze differences in Medicare TS costs. TS retail costs for the 2 most common medications in each potency class (low: hydrocortisone valerate 0.02%& desonide 0.05%; mid: fluocinonide 0.05%& triamcinolone acetonide 0.1%; high: betamethasone dipropionate 0.05%& clobetasol propionate 0.05%) were collected from Medicare.gov. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - April 19, 2021 Category: Dermatology Authors: A. Faletsky, B. Kassamali, J.J. Han, A. Lachance, A. Mostaghimi Tags: Translational Studies Source Type: research

Central serous retinopathy associated with topical oral corticosteroid use: a case report
ConclusionsTo the best of our knowledge, this is the first case of idiopathic central serous retinopathy associated with the use of oral fluocinonide gel. Discontinuing the use of the steroid may result in resolution of the serous retinal detachment and improvement of visual symptoms. Patients and their doctors who prescribe this medication should be aware of this association. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - July 1, 2019 Category: General Medicine Source Type: research

Painful Oral Lesions.
Abstract Painful oral vesiculoerosive diseases (OVD) include lichen planus, pemphigus vulgaris, mucous membrane pemphigoid, erythema multiforme, and recurrent aphthous stomatitis. OVD lesions have an immunopathic cause. Treatment is aimed at reducing the immunologic and the following inflammatory response. The mainstay of OVD management is topical or systemic corticosteroids to include topical triamcinolone, fluocinonide, and clobetasol, whereas systemic medications used in practice can include dexamethasone, prednisone, and prednisolone. Oral herpetic lesions can be primary or recurrent. If management is ...
Source: Herpes - September 9, 2018 Category: Infectious Diseases Authors: Hargitai IA Tags: Dent Clin North Am Source Type: research

Painful Oral Lesions
Painful oral vesiculoerosive diseases (OVD) include lichen planus, pemphigus vulgaris, mucous membrane pemphigoid, erythema multiforme, and recurrent aphthous stomatitis. OVD lesions have an immunopathic cause. Treatment is aimed at reducing the immunologic and the following inflammatory response. The mainstay of OVD management is topical or systemic corticosteroids to include topical triamcinolone, fluocinonide, and clobetasol, whereas systemic medications used in practice can include dexamethasone, prednisone, and prednisolone. Oral herpetic lesions can be primary or recurrent. If management is desired, they can be treat...
Source: Dental Clinics of North America - August 13, 2018 Category: Dentistry Authors: Istvan A. Hargitai Source Type: research

Patients' preferences for different corticosteroid vehicles are highly variable.
DISCUSSION: There was wide variation in patient preference for topical medication vehicles used for treating psoriasis. Several vehicle characteristics were considered important to adherence. Given the marked variation in vehicle preference, topical treatment should be individualized according to patients' preferences. PMID: 29770722 [PubMed - as supplied by publisher] (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - May 19, 2018 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

Marine Develops Chronic Right Knee Granuloma After Initial Injury at The Basic School.
Authors: Prak AH, Dela Rosa KM Abstract With skin lesions that have failed previous treatments, consideration for an atypical mycobacteria, specifically Mycobacterium marinum, infection should be suspected. Importance of the history cannot be stressed as this is a clue that the patient may have been inoculated and infected in the field environment. A marine with chronic right knee plaque for 3 yr that first appeared after a field exercise at The Basic School but worsened despite treatment with clindamycin, TMP-SMX, and incision and drainage in 2012. Examination revealed a 4 × 4 cm pink, pearly, scaly plaq...
Source: Military Medicine - March 22, 2018 Category: International Medicine & Public Health Tags: Mil Med Source Type: research

Long ‐term adherence to topical psoriasis treatment can be abysmal: a 1‐year randomized intervention study using objective electronic adherence monitoring
ConclusionsThis study likely underestimates the challenge of long‐term adherence, as adherence tends to be better in research studies than in clinical practice. This study also did not fully account for primary nonadherence. Adherence to topical treatment is low in the short term and decreased further in the long term, a considerable challenge for dermatologists to address. A reporting intervention may be one of the ways we can improve our patients’ treatment outcomes. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - November 28, 2016 Category: Dermatology Authors: H. Alinia, S. Moradi Tuchayi, J.A. Smith, I.M. Richardson, N. Bahrami, S.C. Jaros, L.F. Sandoval, M.E. Farhangian, K.L. Anderson, K.E. Huang, S.R. Feldman Tags: Medical Dermatology Source Type: research

Long ‐term adherence to topical psoriasis treatment can be abysmal: A one‐year randomized intervention study using objective electronic adherence monitoring
ConclusionsAdherence to topical treatment is low in short term and decreased further in the long term, a considerable challenge for dermatologists to address. A reporting intervention may one of the ways we can improve our patients’ treatment outcomes.This article is protected by copyright. All rights reserved. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - September 23, 2016 Category: Dermatology Authors: H. Alinia, S. Moradi Tuchayi, J.A. Smith, I.M. Richardson, N. Bahrami, S.C. Jaros, L.F. Sandoval, M. E Farhangian, K.L. Anderson, K.E. Huang, S.R. Feldman Tags: Original Article Source Type: research

Effectiveness of topical corticosteroids in addition to antiviral therapy in the management of recurrent herpes labialis: a systematic review and meta-analysis.
CONCLUSION: Treatment with combined therapy is safe and more effective than placebo or antiviral alone for preventing the recurrence of ulcerative lesions in RHL infection. PMID: 25783102 [PubMed - in process] (Source: Herpes)
Source: Herpes - March 20, 2015 Category: Infectious Diseases Authors: Arain N, Paravastu SC, Arain MA Tags: BMC Infect Dis Source Type: research

Effectiveness of topical corticosteroids in addition to antiviral therapy in the management of recurrent herpes labialis: a systematic review and meta-analysis
The objective of this review was to identify the effectiveness of topical corticosteroids in addition to antiviral therapy in the treatment of RHL infection. Methods: A systematic review of randomized clinical trials comparing the efficacy of combined therapy (topical corticosteroids with antiviral) with placebo or antiviral alone in the management of RHL was conducted. MEDLINE, EMBASE, CINAHL, Web of Science, the Cochrane library, and Google Scholar databases were searched. We used RevMan software to conduct the meta-analysis. A fixed-effects model was used for mild to moderate heterogeneity, whereas a random-effects mode...
Source: BMC Infectious Diseases - February 21, 2015 Category: Infectious Diseases Authors: Nasira ArainSharath ParavastuMubashir Arain Source Type: research

Adherence to a five day treatment course of topical fluocinonide 0.1% cream in atopic dermatitis.
Conclusions: Adherence rates with short-term treatment were similar to previously reported rates in longer term treatment studies. However, even non-adherent patients had significant improvement in itch and disease severity. PMID: 24139369 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 23, 2013 Category: Dermatology Authors: Hix E, Gustafson CJ, O'Neill JL, Huang K, Sandoval LF, Harrison J, Clark A, Feldman SR Tags: Dermatol Online J Source Type: research

Topical bexarotene for psoralen plus ultraviolet A–induced photodamage
We present a 58-year-old Caucasian man with follicular mycosis fungoides diagnosed 13 years earlier. His condition was partially controlled over the years with phototherapy with alternating periods of narrowband ultraviolet (UV)B radiation and psoralen plus UVA (PUVA) radiation, 200 sessions, cumulative dose of 1749 J/cm2, discontinued 3 years earlier. For the past 8 years he used topical bexarotene gel 2 to 3 times daily and eventually topical steroids (fluocinonide 0.05% cream). In addition, he had taken acitretin 25 mg 3 times a week for 4 years. He also received treatments for short periods with radiation to isolated t...
Source: Journal of the American Academy of Dermatology - July 21, 2013 Category: Dermatology Authors: Janyana M.D. Deonizio, Sapna Patel Vaghani, Joan Guitart Tags: JAAD Online Source Type: research