Why an integrated view of gene expression studies on hematopoiesis in mouse aging is better than the sum of their parts
A standard approach to studying aging in mice typically involves the isolation of hematopoietic stem cells from two cohorts, namely young and old, from which total RNA is extracted, sequenced, and analyzed through R-based standard protocols. The lists of differentially expressed genes resulting from these analyses are usually interpreted with Gene Ontology classifications. Globally, the human population is aging, with an increased proportion of people in “old age” (over 60 years). This trend leads to a growing demand in aging research, stimulating studies in animal models such as mice, fish, and invertebrates. Recent...
Source: FEBS Letters - April 17, 2024 Category: Biochemistry Authors: Leonid V. Bystrykh Tags: Perspective Source Type: research
I dive for fish in the longest freshwater lake in the world
Nature, Published online: 17 April 2024; doi:10.1038/d41586-024-01099-0Biologist Carolin Sommer-Trembo describes her fascination for fish and why she enjoys doing science in Switzerland. (Source: Nature AOP)
Source: Nature AOP - April 17, 2024 Category: Research Authors: Nikki Forrester Source Type: research
Reducing Nogo-B Improves Hepatic Fibrosis by Inhibiting BACe1-Mediated Autophagy
Conclusion:Nogo-B knockdown prevents HF by directly inhibiting BACe1-mediated autophagy. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - April 17, 2024 Category: Biotechnology Source Type: research
Has food security in the EU countries worsened during the COVID-19 pandemic? Analysis of physical and economic access to food
by Karolina Pawlak, Agata Malak-Rawlikowska, Mariusz Hamulczuk, Marta Skrzypczyk
The aim of the paper is to provide an ex-post assessment of the impact of the COVID-19 pandemic on food insecurity in the EU-27 countries expressed by physical and economic food access. We analysed trade and price effects, together with food insecurity and malnutrition indicators. Actual levels of the indicators were compared with their pre-pandemic magnitudes and/or with counterfactual levels derived from predictive models. We also aimed to compare the objective statistics with the subjective consumers’ perception of their households’ fo...
Source: PLoS One - April 17, 2024 Category: Biomedical Science Authors: Karolina Pawlak Source Type: research
Dietary diversity and preferences among pregnant women and its association with anaemia
This study aims to assess dietary choices of pregnant women and its relationship with their anaemia status.A mixed-method study comprising a survey and three focus group discussions (FGDs). The survey included 380 adult pregnant women with data collected on food choices, preferences and haemoglobin (Hb) status.More than 50% of women in the study had Hb concentration < 11.0 g/dl; mean Hb was 10.24 g/dl (SD = 1.59). Univariate analysis was used to generate descriptive tabulations for socio-demographic characteristics of respondents, dietary choices for women and anaemia status. T-test and bivariate analysis between diet...
Source: Nutrition and Food Science - April 16, 2024 Category: Nutrition Authors: Benedicta Twum - Dei Richmond Aryeetey Linda Nana Esi Aduku Source Type: research
Aflatoxin B1 inhibited the development of primary myoblasts of grass carp (Ctenopharyngodon idella) by degrading extracellular matrix
Ecotoxicol Environ Saf. 2024 Apr 15;276:116332. doi: 10.1016/j.ecoenv.2024.116332. Online ahead of print.ABSTRACTAccording to the International Agency for Research on Cancer (IARC), aflatoxin B1 (AFB1) has been recognized as a major contaminant in food and animal feed and which is a common mycotoxin with high toxicity. Previous research has found that AFB1 inhibited zebrafish muscle development. However, the potential mechanism of AFB1 on fish muscle development is unknown, so it is necessary to conduct further investigation. In the present research, the primary myoblast of grass carp was used as a model, we treated myobla...
Source: Ecotoxicology and Environmental Safety - April 16, 2024 Category: Environmental Health Authors: Xiang-Ning He Wei-Dan Jiang Pei Wu Yang Liu Hong-Mei Ren Xiao-Wan Jin Sheng-Yao Kuang Ling Tang Shu-Wei Li Lin Feng Xiao-Qiu Zhou Source Type: research
Dietary intake changes the associations between long-term exposure to fine particulate matter and the surrogate indicators of insulin resistance
Environ Int. 2024 Apr 10;186:108626. doi: 10.1016/j.envint.2024.108626. Online ahead of print.ABSTRACTThe relationship of fine particulate matter (PM2.5) exposure and insulin resistance remains inclusive. Our study aimed to investigate this association in the project of Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China-PAR). Specifically, we examined the associations between long-term PM2.5 exposure and three surrogate indicators of insulin resistance: the triglyceride-glucose index (TyG), TyG with waist circumference (TyG-WC) and metabolic score for insulin resistance (METS-IR). Additionally, we e...
Source: Environment International - April 16, 2024 Category: Environmental Health Authors: Yanhui Jia Zhi He Fangchao Liu Jianxin Li Fengchao Liang Keyong Huang Jichun Chen Jie Cao Hongfan Li Chong Shen Ling Yu Xiaoqing Liu Dongsheng Hu Jianfeng Huang Yingxin Zhao Yang Liu Xiangfeng Lu Dongfeng Gu Shufeng Chen Source Type: research
Stretchable, antifatigue, and intelligent nanocellulose hydrogel colorimetric film for real-time visual detection of beef freshness
In this study, a nanocellulose hydrogel colorimetric film with enhanced stretchability, antifatigue properties, and color stability was prepared using soy hull nanocellulose (SHNC), polyvinyl alcohol (PVA), sodium alginate (SA), and anthocyanin (Anth) as raw materials. This hydrogel colorimetric film was used to detect beef freshness. The structure and properties (e.g., mechanical, thermal stability and hydrophobicity) of these hydrogel colorimetric films were characterized using different techniques. Fourier-transform infrared spectroscopy revealed the presence of hydrogen and ester bonds in the hydrogel colorimetric film...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Kejin Yu Lina Yang Siyu Zhang Ning Zhang Mengxi Xie Miao Yu Source Type: research
Assessing metal(loid)s-Induced long-term spatiotemporal health risks in Coastal Regions, Bay of Bengal: A chemometric study
Environ Sci Pollut Res Int. 2024 Apr 16. doi: 10.1007/s11356-024-33141-z. Online ahead of print.ABSTRACTDespite sporadic and irregular studies on heavy metal(loid)s health risks in water, fish, and soil in the coastal areas of the Bay of Bengal, no chemometric approaches have been applied to assess the human health risks comprehensively. This review aims to employ chemometric analysis to evaluate the long-term spatiotemporal health risks of metal(loid)s e.g., Fe, Mn, Zn, Cd, As, Cr, Pb, Cu, and Ni in coastal water, fish, and soils from 2003 to 2023. Across coastal parts, studies on metal(loid)s were distributed with 40% in...
Source: Environmental Science and Pollution Research International - April 16, 2024 Category: Environmental Health Authors: Shammi Aktar Abu Reza Md Towfiqul Islam Md Yousuf Mia Jannatun Nahar Jannat Md Saiful Islam Md Abu Bakar Siddique Md Abdullah Al Masud Abubakr M Idris Subodh Chandra Pal Venkatramanan Senapathi Source Type: research
Oral feed-based administration of phage cocktail protects rohu fish (Labeo rohita) against Aeromonas hydrophila infection
Arch Microbiol. 2024 Apr 16;206(5):219. doi: 10.1007/s00203-024-03951-3.ABSTRACTAeromonas hydrophila is one of the major freshwater fish pathogens. In the current study, a cocktail of D6 and CF7 phages was given orally to Labeo rohita to assess phage survival in fish organs as well as to determine the therapeutic efficacy of phage treatment against fish mortality caused by A. hydrophila. In the phage-coated feed, prepared by simple spraying method, phage counts were quite stable for up to 2 months with a decline of ≤ 0.23 log10 and ≤ 1.66 log10 PFU/g feed during 4 oC and room temperature storage. Throughout the experim...
Source: Archives of Microbiology - April 16, 2024 Category: Microbiology Authors: Sumeet Rai Anuj Tyagi Naveen Kumar B T Source Type: research
Can sympathetic induction be a convenient technique for breeding Amblypharyngodon mola (Hamilton, 1822)?
Anim Reprod Sci. 2024 Apr 15;264:107473. doi: 10.1016/j.anireprosci.2024.107473. Online ahead of print.ABSTRACTMola carplet (Amblypharyngodon mola) is one of the most popular small fish species of the Indian subcontinent. There are limited studies on captive breeding of this species, which is important for aquaculture and the conservation prospects of this species. The conventional induced breeding method using an inducing agent (GnRHa and dopamine antagonist) is one of the most effective and prevalent methods of breeding fish. It is a laborious and time-consuming process, particularly in mass fish breeding and in lieu of ...
Source: Animal Reproduction Science - April 16, 2024 Category: Zoology Authors: Sanayaima Singha Shivendra Kumar Kalpajit Gogoi Pabitra Kumar Saharia Rajdeep Dutta Arnab Narayan Patowary Sangipran Baishya Kaustubh Bhagawati Biswajyoti Bordoloi Dipak Kumar Sarma Source Type: research
Stretchable, antifatigue, and intelligent nanocellulose hydrogel colorimetric film for real-time visual detection of beef freshness
In this study, a nanocellulose hydrogel colorimetric film with enhanced stretchability, antifatigue properties, and color stability was prepared using soy hull nanocellulose (SHNC), polyvinyl alcohol (PVA), sodium alginate (SA), and anthocyanin (Anth) as raw materials. This hydrogel colorimetric film was used to detect beef freshness. The structure and properties (e.g., mechanical, thermal stability and hydrophobicity) of these hydrogel colorimetric films were characterized using different techniques. Fourier-transform infrared spectroscopy revealed the presence of hydrogen and ester bonds in the hydrogel colorimetric film...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Kejin Yu Lina Yang Siyu Zhang Ning Zhang Mengxi Xie Miao Yu Source Type: research
Dietary intake changes the associations between long-term exposure to fine particulate matter and the surrogate indicators of insulin resistance
Environ Int. 2024 Apr 10;186:108626. doi: 10.1016/j.envint.2024.108626. Online ahead of print.ABSTRACTThe relationship of fine particulate matter (PM2.5) exposure and insulin resistance remains inclusive. Our study aimed to investigate this association in the project of Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China-PAR). Specifically, we examined the associations between long-term PM2.5 exposure and three surrogate indicators of insulin resistance: the triglyceride-glucose index (TyG), TyG with waist circumference (TyG-WC) and metabolic score for insulin resistance (METS-IR). Additionally, we e...
Source: Environment International - April 16, 2024 Category: Environmental Health Authors: Yanhui Jia Zhi He Fangchao Liu Jianxin Li Fengchao Liang Keyong Huang Jichun Chen Jie Cao Hongfan Li Chong Shen Ling Yu Xiaoqing Liu Dongsheng Hu Jianfeng Huang Yingxin Zhao Yang Liu Xiangfeng Lu Dongfeng Gu Shufeng Chen Source Type: research
Aflatoxin B1 inhibited the development of primary myoblasts of grass carp (Ctenopharyngodon idella) by degrading extracellular matrix
Ecotoxicol Environ Saf. 2024 Apr 15;276:116332. doi: 10.1016/j.ecoenv.2024.116332. Online ahead of print.ABSTRACTAccording to the International Agency for Research on Cancer (IARC), aflatoxin B1 (AFB1) has been recognized as a major contaminant in food and animal feed and which is a common mycotoxin with high toxicity. Previous research has found that AFB1 inhibited zebrafish muscle development. However, the potential mechanism of AFB1 on fish muscle development is unknown, so it is necessary to conduct further investigation. In the present research, the primary myoblast of grass carp was used as a model, we treated myobla...
Source: Ecotoxicology and Environmental Safety - April 16, 2024 Category: Environmental Health Authors: Xiang-Ning He Wei-Dan Jiang Pei Wu Yang Liu Hong-Mei Ren Xiao-Wan Jin Sheng-Yao Kuang Ling Tang Shu-Wei Li Lin Feng Xiao-Qiu Zhou Source Type: research
Can sympathetic induction be a convenient technique for breeding Amblypharyngodon mola (Hamilton, 1822)?
Anim Reprod Sci. 2024 Apr 15;264:107473. doi: 10.1016/j.anireprosci.2024.107473. Online ahead of print.ABSTRACTMola carplet (Amblypharyngodon mola) is one of the most popular small fish species of the Indian subcontinent. There are limited studies on captive breeding of this species, which is important for aquaculture and the conservation prospects of this species. The conventional induced breeding method using an inducing agent (GnRHa and dopamine antagonist) is one of the most effective and prevalent methods of breeding fish. It is a laborious and time-consuming process, particularly in mass fish breeding and in lieu of ...
Source: Animal Reproduction Science - April 16, 2024 Category: Zoology Authors: Sanayaima Singha Shivendra Kumar Kalpajit Gogoi Pabitra Kumar Saharia Rajdeep Dutta Arnab Narayan Patowary Sangipran Baishya Kaustubh Bhagawati Biswajyoti Bordoloi Dipak Kumar Sarma Source Type: research
