Distribution and bioaccumulation of trace elements in two Cyprinidae fish species in the Indus river, Pakistan, including the impact of hydraulic structure on macroinvertebrates' biodiversity
Environ Res. 2024 Apr 4:118882. doi: 10.1016/j.envres.2024.118882. Online ahead of print.ABSTRACTThe concentration of trace elements (chromium, lead, zinc, copper, manganese, and iron) was determined in water, sediment and tissues of two Cyprinidae fish species - Labeo rohita and Tor putitora - collected from the eight sampling stations of Indus River in 2022 for four successive seasons (autumn, winter, spring, summer), and also study the present condition of macroinvertebrates after the construction of hydraulic structure. The obtained results of trace element concentrations in the Indus River were higher than the accepta...
Source: Environmental Research - April 6, 2024 Category: Environmental Health Authors: Muhammad Waseem Boota Shan-E-Hyder Soomro Haoming Xia Yaochen Qin Mian Adnan Kakakhel Chaode Yan Luo Weiran Jikun Xu Source Type: research
Longitudinal changes in adverse effects reporting in multiple dietary supplement classifications: The US military dietary supplement use study
In conclusion, AEs reported at baseline did not deter many participants from using DSs in the follow-up period, and many SMs reporting AEs at baseline continued reporting them at follow-up.PMID:38582347 | DOI:10.1016/j.fct.2024.114635 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 6, 2024 Category: Food Science Authors: Joseph J Knapik Daniel W Trone Ryan A Steelman Harris R Lieberman Source Type: research
Blowflies (Diptera: Calliphoridae) as potential mechanical vectors of the protozoan cyst and helminthic eggs in Kashmir Himalaya, India
AbstractBlowflies (Diptera: Calliphoridae) are an important group of non-biting flies that are potential mechanical vectors of protozoan and helminthic pathogens. The present study was carried out to isolate and identify protozoan cysts and helminthic eggs transmitted by blowflies. Surveys were carried out at six different sites, viz., butcher shops, fish markets, garbage piles, water bodies, and open vegetation in the Kashmir Himalaya. The flies were collected with the help of a sweeping net and using day-old beef liver as bait from March 2021 to February 2023. A total of 968 blowflies were collected, out of which 83 were...
Source: Journal of Parasitic Diseases - April 6, 2024 Category: Parasitology Source Type: research
Secondary plasma cell leukaemia (PCL) with plasmablastic morphology
AbstractA 71-year-old female with relapsed IgA lambda myeloma developed progressive cytopenia. The peripheral blood film showed 5% blastoid cells. Flow cytometry analysis was indicative of plasma cells. The bone marrow smear was packed with plasmablasts. Target CD138-cell FISH and molecular karyotyping identified a complex genome. NGS identified high-risk mutations. Bone marrow histology confirmed myeloma with no evidence of acute leukaemia. The patient was diagnosed with plasmablastic progression of myeloma and secondary PCL. Secondary PCL patients have a poor prognosis. It is essential to recognize this subtype and explo...
Source: Journal of Hematopathology - April 6, 2024 Category: Pathology Source Type: research
Reliable detection of RNA in hippocampus sections of mice by FISH up to a post-mortem delay of 24 h
In this study, we show that this also applies to the localization of RNA and in particular to the RNA of microglia-specific receptor proteins using the probes and the RNAscope™ Multiplex Fluorescent Detection Kit v2 from Advanced Cell Diagnostics. Brains were removed from killed mice after different PM delays and processed into paraffin sections. In sections of brains from animals whose cadavers had been kept at room temperature (21 °C) before tissue removal, ubiquitously expressed RNAs of genes with low to high expression levels (Polr2a, PPIB, and UBC) were reliably detected in the brain sections even if tissue remov...
Source: Histochemistry and Cell Biology - April 6, 2024 Category: Biomedical Science Source Type: research
Mechanical, optical, chemical, and biological evaluations of fish scale-derived scaffold for corneal replacements: A systematic review
This study aims to gather scattered pieces of information about the mentioned performances and fabrication techniques of FSSs for corneal replacements. Sorted from four scientific databases and using the PRISMA checklist, eleven relevant articles are collected. FSSs are commonly fabricated using decellularization and decalcification processes, generating FSSs with parallel multilayers or crossed fibers with topographic microchannels. In the collected studies, similar mechanical properties of FSSs to native tissues are discovered, as well as good transparency, light remittance, but poorer refractive indexes than native tiss...
Source: International Journal of Biological Macromolecules - April 5, 2024 Category: Biochemistry Authors: Kevin Tjoa Muhammad Hanif Nadhif Sakinasha Siva Utami Samuel Ronny Kusuma Prasandhya Yusuf Astagiri Gitalisa Andayani Adriono Source Type: research
Parental exposure to antidepressants has lasting effects on offspring? A case study with zebrafish
Chemosphere. 2024 Apr 3:141851. doi: 10.1016/j.chemosphere.2024.141851. Online ahead of print.ABSTRACTFish have common neurotransmitter pathways with humans, exhibiting a significant degree of conservation and homology. Thus, exposure to fluoxetine makes fish potentially susceptible to biochemical and physiological changes, similarly to what is observed in humans. Over the years, several studies demonstrated the potential effects of fluoxetine on different fish species and at different levels of biological organization. However, the effects of parental exposure to unexposed offspring remain largely unknown. The consequence...
Source: Chemosphere - April 5, 2024 Category: Chemistry Authors: Daniela Correia Marina Bellot J úlia Goyenechea Eva Prats Hugo Moro Cristian G ómez-Canela Juliette Bedrossiantz Niki Tagkalidou Carla S S Ferreira Demetrio Rald úa In ês Domingues Melissa Faria Miguel Oliveira Source Type: research
Ecotoxicity of environmental concentrations of bifenthrin in larval freshwater snail Bellamya aeruginosa
In this study, larval B. aeruginosa within 24 h of birth were exposed to 0, 30 or 300 ng/L of BF for 30 days, and then the toxic effects from molecular to individual levels were comprehensively evaluated in all the three treatment groups. It was found that BF at 300 ng/L caused the mortality of snails. Furthermore, BF affected snail behaviors, evidenced by reduced crawling distance and crawling speed. The hepatopancreas of snails in the two BF exposure groups showed significant pathological changes, including increase in the number of yellow granules and occurrence of hemocyte infiltration, epithelial cell thinning, and ne...
Source: Chemosphere - April 5, 2024 Category: Chemistry Authors: Guixin Han Dianping Bu Ren Kong Kai Huang Chunsheng Liu Source Type: research
Antibacterial activity of a short de novo designed peptide against fish bacterial pathogens
Amino Acids. 2024 Apr 5;56(1):28. doi: 10.1007/s00726-024-03388-4.ABSTRACTIn the face of increasing antimicrobial resistance in aquaculture, researchers are exploring novel substitutes to customary antibiotics. One potential solution is the use of antimicrobial peptides (AMPs). We aimed to design and evaluate a novel, short, and compositionally simple AMP with potent activity against various bacterial pathogens in aquaculture. The resulting peptide, KK12YW, has an amphipathic nature and net charge of + 7. Molecular docking experiments disclosed that KK12YW has a strong affinity for aerolysin, a virulence protein produced b...
Source: Amino Acids - April 5, 2024 Category: Biochemistry Authors: Raja Aadil Hussain Bhat Victoria C Khangembam Vinita Pant Ritesh Shantilal Tandel Pramod Kumar Pandey Dimpal Thakuria Source Type: research
Parental exposure to antidepressants has lasting effects on offspring? A case study with zebrafish
Chemosphere. 2024 Apr 3:141851. doi: 10.1016/j.chemosphere.2024.141851. Online ahead of print.ABSTRACTFish have common neurotransmitter pathways with humans, exhibiting a significant degree of conservation and homology. Thus, exposure to fluoxetine makes fish potentially susceptible to biochemical and physiological changes, similarly to what is observed in humans. Over the years, several studies demonstrated the potential effects of fluoxetine on different fish species and at different levels of biological organization. However, the effects of parental exposure to unexposed offspring remain largely unknown. The consequence...
Source: Chemosphere - April 5, 2024 Category: Chemistry Authors: Daniela Correia Marina Bellot J úlia Goyenechea Eva Prats Hugo Moro Cristian G ómez-Canela Juliette Bedrossiantz Niki Tagkalidou Carla S S Ferreira Demetrio Rald úa In ês Domingues Melissa Faria Miguel Oliveira Source Type: research
Ecotoxicity of environmental concentrations of bifenthrin in larval freshwater snail Bellamya aeruginosa
In this study, larval B. aeruginosa within 24 h of birth were exposed to 0, 30 or 300 ng/L of BF for 30 days, and then the toxic effects from molecular to individual levels were comprehensively evaluated in all the three treatment groups. It was found that BF at 300 ng/L caused the mortality of snails. Furthermore, BF affected snail behaviors, evidenced by reduced crawling distance and crawling speed. The hepatopancreas of snails in the two BF exposure groups showed significant pathological changes, including increase in the number of yellow granules and occurrence of hemocyte infiltration, epithelial cell thinning, and ne...
Source: Chemosphere - April 5, 2024 Category: Chemistry Authors: Guixin Han Dianping Bu Ren Kong Kai Huang Chunsheng Liu Source Type: research
Antibacterial activity of a short de novo designed peptide against fish bacterial pathogens
Amino Acids. 2024 Apr 5;56(1):28. doi: 10.1007/s00726-024-03388-4.ABSTRACTIn the face of increasing antimicrobial resistance in aquaculture, researchers are exploring novel substitutes to customary antibiotics. One potential solution is the use of antimicrobial peptides (AMPs). We aimed to design and evaluate a novel, short, and compositionally simple AMP with potent activity against various bacterial pathogens in aquaculture. The resulting peptide, KK12YW, has an amphipathic nature and net charge of + 7. Molecular docking experiments disclosed that KK12YW has a strong affinity for aerolysin, a virulence protein produced b...
Source: Amino Acids - April 5, 2024 Category: Biochemistry Authors: Raja Aadil Hussain Bhat Victoria C Khangembam Vinita Pant Ritesh Shantilal Tandel Pramod Kumar Pandey Dimpal Thakuria Source Type: research
Occurrence and seasonal variations of antibiotic micro-pollutants in the Wei River, China
In this study, a systematic monitoring campaign of 30 antibiotics belonging to tetracyclines (TCs), macrolides (MLs), fluoroquinolones (FQs) and sulfonamides (SAs) was performed in the Xi'an section of the Wei River during three sampling events (December 2021, June 2022, and September 2022). The total concentrations of antibiotics in water ranged from 297 to 461 ng/L with high detection frequencies ranging from 45% to 100% for the various antibiotics. A marked seasonal variation in concentrations was found with total antibiotic concentrations in winter being 1.5 and 2 times higher than those in the summer and autumn season...
Source: Environmental Research - April 5, 2024 Category: Environmental Health Authors: Shengkai Cao Peng Zhang Crispin Halsall Zhimin Hou Linke Ge Source Type: research
Parental exposure to antidepressants has lasting effects on offspring? A case study with zebrafish
Chemosphere. 2024 Apr 3:141851. doi: 10.1016/j.chemosphere.2024.141851. Online ahead of print.ABSTRACTFish have common neurotransmitter pathways with humans, exhibiting a significant degree of conservation and homology. Thus, exposure to fluoxetine makes fish potentially susceptible to biochemical and physiological changes, similarly to what is observed in humans. Over the years, several studies demonstrated the potential effects of fluoxetine on different fish species and at different levels of biological organization. However, the effects of parental exposure to unexposed offspring remain largely unknown. The consequence...
Source: Chemosphere - April 5, 2024 Category: Chemistry Authors: Daniela Correia Marina Bellot J úlia Goyenechea Eva Prats Hugo Moro Cristian G ómez-Canela Juliette Bedrossiantz Niki Tagkalidou Carla S S Ferreira Demetrio Rald úa In ês Domingues Melissa Faria Miguel Oliveira Source Type: research
Toxic responses of environmental concentrations of bifenthrin in larval freshwater snail Bellamya aeruginosa
In this study, larval B. aeruginosa within 24 h of birth were exposed to 0, 30 or 300 ng/L of BF for 30 days, and then the toxic effects from molecular to individual levels were comprehensively evaluated in all the three treatment groups. It was found that BF at 300 ng/L caused the mortality of snails. Furthermore, BF affected snail behaviors, evidenced by reduced crawling distance and crawling speed. The hepatopancreas of snails in the two BF exposure groups showed significant pathological changes, including increase in the number of yellow granules and occurrence of hemocyte infiltration, epithelial cell thinning, and ne...
Source: Chemosphere - April 5, 2024 Category: Chemistry Authors: Guixin Han Dianping Bu Ren Kong Kai Huang Chunsheng Liu Source Type: research
