Fight Aging! Newsletter, April 8th 2024
In this study, we tested a stem cell secretome product, which contains extracellular vesicles and growth factors, cytoskeletal remodeling factors, and immunomodulatory factors. We examined the effects of 4 weeks of 2×/week unilateral intramuscular secretome injections (quadriceps) in ambulatory aged male C57BL/6 mice (22-24 months) compared to saline-injected aged-matched controls. Secretome delivery substantially increased whole-body lean mass and decreased fat mass, corresponding to higher myofiber cross-sectional area and smaller adipocyte size, respectively. Secretome-treated mice also had greater whole-bod...
Source: Fight Aging! - April 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Lewy Body Disease May Be More Common than Thought
Access to human brain tissue for medical research is more limited than most people realize is the case, and, for obvious reasons, far too little of the available tissue data covers the early stages of disease. This limitation is one of the factors slowing the pace of research into age-related neurodegenerative conditions. Here, for example, researchers make use of an unusual resource to show that the prevalence of Lewy body disease may be greater than presently thought, with pathology beginning in the 50s, even if there are no outright symptoms of disease at that stage. Lewy body disease is the second most common ...
Source: Fight Aging! - April 2, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

“The Greatest Scientist of All Time” says Scientific American. Who is it?
BY MIKE MAGEE When it comes to our earthly survival as a human species, words are often under-powered and off-the-mark. Clearer concepts, definitions and terms are required for clarity. Here are five terms that are useful and worth remembering: Planetary Boundaries Earth Systems Human Perturbations Planetary Scale Destabilization Holocene Epoch vs. Anthropogenic Epoch  These terms all tie back to a single source – a child of World War II, only seven when his home in Amsterdam was overrun by Nazis. His father was a waiter, his mother a cook in a local hospital. He’d later recall with a sh...
Source: The Health Care Blog - September 11, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Non-Health Chemistry Mike Magee Ozone Paul Crutzen Scientific American Source Type: blogs

Can You Use Saunas With Hypertension?
Conclusion So, can you use saunas with hypertension? With the right precautions and guidance from a healthcare provider, it appears you can indeed enjoy the soothing warmth of a sauna. Regular sauna use might even provide certain health benefits. However, it’s vital to monitor your blood pressure regularly, stay well-hydrated, and pay close attention to how your body is reacting. Sauna bathing should be a stress-relieving, enjoyable experience. If it leads to discomfort or concern, it’s best to cool down and consult your healthcare provider. References Sauna bathing is associated with ...
Source: The EMT Spot - May 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Are crypto currencies destroying the planet?
TL:DR – Bitcoin mining uses vast arrays of energy-hungry computers many of which are powered with an unsustainable, non-renewable energy supply, generating enormous carbon emissions. It is estimated that Bitcoin is currently wasting 140 terawatt-hours of electricity annually and producing 70 megatonnes of carbon emissions each year. Bitcoin is a form of digital currency. Each Bitcoin has a digital ledger, a blockchain, that records all transactions and is at the heart of the value in the currency. Bitcoin transactions are typically irreversible and can be made anonymously, providing a level of privacy. It operates o...
Source: David Bradley Sciencebase - Songs, Snaps, Science - April 11, 2023 Category: Science Authors: David Bradley Tags: Environment Source Type: blogs

Dementia and National Security, Finland Joins NATO, the Four-Day School Week: RAND Weekly Recap
This weekly recap focuses on the risk that dementia could pose to national security, Finland ' s NATO membership, the downside of a four-day school week, and more. (Source: The RAND Blog)
Source: The RAND Blog - April 7, 2023 Category: Health Management Authors: RAND Corporation Source Type: blogs

The New Deal and Recovery, Part 27: Deposit Insurance
ConclusionPart 27: Deposit Insurance_____________________[1] To this list we might add a fourth item, noted by Golembe in a subsequentinterview, to wit: that the deposit " insurance " provided for by the 1933 Banking Act wasn ' t really insurance at all. Unlike genuine insurance policies, it covers depositors for losses regardless of whether the losses were due to recklessness on their or their banks ' part. And unlike genuine insurance funds, the FDIC ' s insurance " fund " is an accounting fiction, the truth being that the " premiums " it collects from banks go into the federal government ' s general coffers. " The gover...
Source: Cato-at-liberty - March 28, 2023 Category: American Health Authors: George Selgin Source Type: blogs

The northern lights aren ’ t in my eyes – Aurora borealis
Lots of lucky locals, by which I mean people a bit further north in Norfolk saw the northern lights, the Aurora Borealis, in Norfolk and elsewhere. There is a slight possibility of seeing them in Cambridgeshire although finding somewhere with little light pollution around here is a tough call, but more to the point it’s been cloudy and wet when other places have had their lightshow these last couple of nights. In recent years they have been observed from Devon and Cornwall. Aurora borealis at Vestrahorn, Southern Iceland (Credit: Simaron) So, what are the northern lights? The northern lights are a natural phenomenon ...
Source: David Bradley Sciencebase - Songs, Snaps, Science - March 24, 2023 Category: Science Authors: David Bradley Tags: Astronomy Source Type: blogs

A discussion on mental health during the holidays [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! In this episode, we welcome Jennifer Shaer, a pediatrician, to discuss the issue of physician suicide rates and how the holidays can impact mental health. Despite being one of the happiest countries in the world, Scandinavian countries like Finland and Denmark have some of Read more… A discussion on mental health during the holidays [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 7, 2023 Category: General Medicine Authors: Tags: Podcast Psychiatry Source Type: blogs

Trial By Error: An Upcoming “ Biopsychosocial ” Long Covid Conference in Finland
By David Tuller, DrPH What is it with the health care establishments in northern Europe? Why are they so devoted to non-evidence-based approaches to treating serious medical conditions? Why do they trust arguably fraudulent research, like the PACE trial and Professor Esther Crawley’s pediatric Lightning Process study? Why are the authors of these studies respected … Trial By Error: An Upcoming “Biopsychosocial” Long Covid Conference in Finland Read More » (Source: virology blog)
Source: virology blog - February 23, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized Finland gupta liira Long Covid Sharpe Source Type: blogs

Trial By Error: An Upcoming “ Biopsychosocial ” Long Covid Conference in Finland
By David Tuller, DrPH What is it with the health care establishments in northern Europe? Why are they so devoted to non-evidence-based approaches to treating serious medical conditions? Why do they trust arguably fraudulent research, like the PACE trial and Professor Esther Crawley’s pediatric Lightning Process study? Why are the authors of these studies respected […] (Source: virology blog)
Source: virology blog - February 23, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized Finland gupta liira Long Covid Sharpe Source Type: blogs

Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed. The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Viral Infection in Middle Age Correlates with Later Dementia Risk
A range of evidence suggests that persistent viral infection contributes to the risk of suffering neurodegenerative conditions such as Alzheimer's disease. This may be due to mechanisms relating to amyloid-β accumulation, in its role as an anti-microbial peptide, a part of the innate immune system. It may have more to do with lasting chronic inflammation subsequent to infection. Researchers here note another addition to the epidemiological data on this topic, in this case linking severe infections requiring hospitalization with later dementia risk. The effect sizes here are large and last for a long time following infecti...
Source: Fight Aging! - February 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Evidence Calls “Housing First” Homelessness Strategy into Question
Vanessa Brown Calder and Jordan GygiLast month, the Biden administration unveileda  new federal plan to address homelessness, with the goal of reducing homelessness 25 percent by 2025. The plan ’s foundation rests on an approach known as Housing First, a philosophy for addressing the issue of homelessness that emphasizes the need for permanent housing before tackling other issues, such as mental health problems or substance use disorder.[1] Proponents of this method advocate providing the homeless with housing whether or not they have a  job or overcome other obstacles to stability. Once the need for housing is addres...
Source: Cato-at-liberty - January 19, 2023 Category: American Health Authors: Vanessa Brown Calder, Jordan Gygi Source Type: blogs

Improved Membrane Coating for Anti-Cancer Nanoparticles
Scientists at the University of Eastern Finland have developed a technique that lets them improve the coating of nanoparticles when using cell membranes. Cell membranes offer a lot of benefits as a coating for synthetic nanoparticles, including shielding from the immune system, prolonged circulation times and improved tumor accumulation. However, current approaches to coating nanoparticles with cell membranes often result in an incomplete covering. These researchers realized that a simple technique involving adding some additional phospholipids during production was enough to increase the membrane fluidity of the coati...
Source: Medgadget - November 8, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine Nanomedicine Oncology UniEastFinland Source Type: blogs