A two ‐component model of hair cortisol concentration in fibromyalgia: Independent effects of pain chronicity and severity
ConclusionsThese results support the existence of a dysfunction in the regulation of the HPA axis in FM and its possible contribution to chronic pain development.SignificanceThis is the first study to assess hair cortisol concentrations in a specific sample of patients with fibromyalgia (FM). This method is especially useful for the assessment of long-term regular cortisol excretion. Results showed a two-component model for explaining cortisol levels: disease chronicity, with a negative effect, and symptom severity, with a positive effect. This suggests that severe pain/stress evokes higher cortisol levels at earlier stage...
Source: European Journal of Pain - December 16, 2023 Category: Anesthesiology Authors: G. A. Reyes  del Paso, A. Garcia‐Hernandez, A. M. Contreras‐Merino, C. M. Galvez‐Sánchez, P. de la Coba, C. I. Montoro, D. M. Davydov Tags: ORIGINAL ARTICLE Source Type: research

IJERPH, Vol. 20, Pages 7185: Assessing Ethnic Minority Representation in Fibromyalgia Clinical Trials: A Systematic Review of Recruitment Demographics
amani The under-representation of non-White participants in Western countries in clinical research has received increased attention, due to recognized physiological differences between ethnic groups, which may affect the efficacy and optimal dosage of some treatments. This review assessed ethnic diversity in pharmaceutical trials for fibromyalgia, a poorly understood chronic pain disorder. We also investigated longitudinal change to non-White participant proportions in trials and non-White participants’ likelihood to discontinue with fibromyalgia research between trial stages (retention). First, we identi...
Source: International Journal of Environmental Research and Public Health - December 15, 2023 Category: Environmental Health Authors: Peter Henley Tanimola Martins Reza Zamani Tags: Systematic Review Source Type: research

Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: Cancer Control)
Source: Cancer Control - December 14, 2023 Category: Cancer & Oncology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research

Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 14, 2023 Category: Drugs & Pharmacology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research

Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research

Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - December 14, 2023 Category: Drugs & Pharmacology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research

Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study
CONCLUSIONS: The oxygen-ozone therapy is a sound opportunity for breast cancer patients to reduce anti-aromatase-induced pain, fatigue, and musculoskeletal symptoms.PMID:38095411 | DOI:10.26355/eurrev_202312_34602 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - December 14, 2023 Category: Drugs & Pharmacology Authors: U Tirelli L Valdenassi M Franzini S Pandolfi R Fisichella S Chirumbolo Source Type: research

Fibromyalgia interventions, obstacles and prospects: narrative review
Acta Myol. 2023 Sep 30;42(2-3):71-81. doi: 10.36185/2532-1900-334. eCollection 2023.ABSTRACTThis review aims to increase awareness and improve understanding, diagnosis, and management of fibromyalgia - a complex, distressing health challenge that significantly impacts people's lives due to its variable nature and lack of clear diagnostic markers. Healthcare professionals must assist those with this condition and improve their general quality of life. Further, they can do a lot to improve the lives of people with Fibromyalgia by resolving diagnostic hurdles, promoting collaboration, supporting patient advocacy, advancing me...
Source: Acta Myologica - December 13, 2023 Category: Neurology Authors: Afshan Zeeshan Wasti Amal M H Mackawy Amal Hussain Mohsina Huq Hanane Ahmed Anjuman Gul Memon Source Type: research