Genitourinary toxicity in patients receiving TURP prior to hypofractionated radiotherapy for clinically localized prostate cancer: A scoping review
CONCLUSION: For those who have undergone prior TURP hypofractionated radiotherapy may increase the risk of late urinary toxicity, particularly hematuria. Those with persisting bladder dysfunction following TURP are at greatest risk and careful management of these men is required. Close collaboration between urologists and radiation oncologists is recommended to discuss the management of patients with residual baseline bladder dysfunction prior to commencing hypofractionated radiotherapy.PMID:38503591 | DOI:10.1016/j.urolonc.2024.02.011 (Source: Urologic Oncology)
Source: Urologic Oncology - March 19, 2024 Category: Urology & Nephrology Authors: Thomas Neerhut Richard Grills Rod Lynch Patrick Daniel Preece Kathryn McLeod Source Type: research
Interstitial needles versus intracavitary applicators only for locally advanced cervical cancer: results from real-life dosimetric comparisons
ConclusionHR-CTV coverage was higher with IC/IS IGABT than with IC IGABT, with lower doses to the OAR in patients managed for LACC after RCT. Interstitial brachytherapy in the management of LACC after radiotherapy provides better coverage of the target volumes, this could contribute to better local control and improved survival of patients. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 19, 2024 Category: Cancer & Oncology Source Type: research
Spatially Fractionated Radiation Therapy in Sarcomas: A Large Single-Institution Experience
CONCLUSIONS: The current series is the largest to date documenting outcomes for SFRT in sarcomas. Our results suggest combined SFRT with EBRT is associated with a favorable toxicity profile and high rates of symptomatic and radiographic responses for metastatic or unresectable sarcomas.PMID:38495033 | PMC:PMC10943518 | DOI:10.1016/j.adro.2023.101401 (Source: Adv Data)
Source: Adv Data - March 18, 2024 Category: Epidemiology Authors: Safia K Ahmed Ivy A Petersen Michael P Grams Randi R Finley Michael G Haddock Dawn Owen Source Type: research
Spatially Fractionated Radiation Therapy in Sarcomas: A Large Single-Institution Experience
CONCLUSIONS: The current series is the largest to date documenting outcomes for SFRT in sarcomas. Our results suggest combined SFRT with EBRT is associated with a favorable toxicity profile and high rates of symptomatic and radiographic responses for metastatic or unresectable sarcomas.PMID:38495033 | PMC:PMC10943518 | DOI:10.1016/j.adro.2023.101401 (Source: Adv Data)
Source: Adv Data - March 18, 2024 Category: Epidemiology Authors: Safia K Ahmed Ivy A Petersen Michael P Grams Randi R Finley Michael G Haddock Dawn Owen Source Type: research
A Randomized Trial Comparing Quality of Life After LDR or HDR Prostate Brachytherapy Boost with Pelvic External Beam Radiation Therapy
CONCLUSIONS: Patient experience for combined EBRT and prostate BT is improved with HDR BT. Urinary QoL improves over time to be equivalent between the 2 modalities after 18 months, but LDR patients report lasting bowel symptoms.PMID:38493901 | DOI:10.1016/j.ijrobp.2024.02.064 (Source: Health Physics)
Source: Health Physics - March 17, 2024 Category: Physics Authors: Juanita Crook Nikitha Moideen Greg Arbour Felipe Castro C ánovas Cynthia Araujo Deidre Batchelar Ross Halperin Michelle Hilts David Kim David Petrik Jim Rose J C Cheng Francois Bachand Source Type: research
Treatment intensification strategies for men undergoing definitive radiotherapy for high-risk prostate cancer
ConclusionTreatment intensification using a combination of EBRT, advanced hormonal therapies, and brachytherapy may improve patient outcomes and survival in men with high-risk prostate cancer. Shared decision-making between patients and multidisciplinary teams of radiation oncologists, urologists, and medical oncologists is essential for personalizing care in this setting and deciding which strategies make sense for individual patients. (Source: World Journal of Urology)
Source: World Journal of Urology - March 16, 2024 Category: Urology & Nephrology Source Type: research
Radiotherapy in localized prostate cancer: a multicenter analysis evaluating tumor control and late toxicity after brachytherapy and external beam radiotherapy in 1293 patients
CONCLUSION: All types of therapy were effective and well received. HDR-BT caused the least late toxicities, especially GI.PMID:38488901 | DOI:10.1007/s00066-024-02222-w (Source: Cancer Control)
Source: Cancer Control - March 15, 2024 Category: Cancer & Oncology Authors: Matthias Moll Elisabeth Nechvile Christian Kirisits Oxana Komina Thomas Pajer Bettina Kohl Marcin Miszczyk Joachim Widder Tomas-Hendrik Knocke-Abulesz Gregor Goldner Source Type: research
Radiotherapy in localized prostate cancer: a multicenter analysis evaluating tumor control and late toxicity after brachytherapy and external beam radiotherapy in 1293 patients
ConclusionAll types of therapy were effective and well received. HDR-BT caused the least late toxicities, especially GI. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - March 15, 2024 Category: Cancer & Oncology Source Type: research
A Randomized Trial Comparing Quality of Life After LDR or HDR Prostate Brachytherapy Boost with Pelvic External Beam Radiation Therapy
To compare health-related Quality of Life (QoL) in urinary, bowel and sexual domains after combined external beam radiotherapy (EBRT) and either low dose rate (LDR) or high dose rate (HDR) prostate brachytherapy (BT). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 15, 2024 Category: Radiology Authors: Juanita Crook, Nikitha Moideen, Greg Arbour, Felipe Castro C ánovas, Cynthia Araujo, Deidre Batchelar, Ross Halperin, Michelle Hilts, David Kim, David Petrik, Jim Rose, JC Cheng, Francois Bachand Tags: Clinical Investigation Source Type: research
A Randomized Trial Comparing Quality of Life After Low-Dose Rate or High-Dose Rate Prostate Brachytherapy Boost With Pelvic External Beam Radiation Therapy
To compare health-related quality of life (QoL) in urinary, bowel, and sexual domains after combined external beam radiation therapy (EBRT) and either low-dose rate (LDR) or high-dose rate (HDR) prostate brachytherapy (BT). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 15, 2024 Category: Radiology Authors: Juanita Crook, Nikitha Moideen, Greg Arbour, Felipe Castro, Cynthia Araujo, Deidre Batchelar, Ross Halperin, Michelle Hilts, David Kim, David Petrik, Jim Rose, J.C. Cheng, Francois Bachand Tags: CLINICAL INVESTIGATION Source Type: research
Safety and Toxicity of Iopofosine I-131 with External Beam Radiation Therapy (EBRT) in Recurrent or Metastatic Head and Neck Cancer (HNC): Results of a Phase 1 Study
Retreatment of recurrent HNC is often limited by tumor adherence to critical structures or normal tissue tolerance to radiation therapy. Iopofosine I-131 (CLR 131) is a novel targeted small molecular phospholipid ether (PLE) drug conjugate that delivers iodine-131 selectively to malignant tumor cells optimized through specialized regions called lipid rafts. Radiation exposure is selective to cancer cells due to the interaction of the PLE with the highly enriched lipid rafts of the plasma membrane, which are non-reliant on cell surface markers. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 14, 2024 Category: Radiology Authors: J.Y. Bruce, A. Burr, R.J. Kimple, M. Yu, D. Trask, S. Piaskowski, K. Oliver, J. Longcor, S.Y. Cho, B. Bednarz, P.M. Harari Tags: 149 Source Type: research
External radiation therapy of primary central nervous system tumors - current trends and practice
Magy Onkol. 2024 Mar 14;68(1):37-50. Epub 2023 Oct 22.ABSTRACTThe family of primary central nervous system (CNS) tumors is a highly heterogeneous group of diseases. In the complex care of CNS tumors, in addition to surgical and systemic treatments, modern external beam radiation therapy (EBRT) plays a prominent role. This summary article provides an overview of the current indications related to EBRT, diagnostic procedures, contouring, planning, and radiation therapy techniques and applications that can be used in daily routine for adults' most common primary CNS tumors.PMID:38484374 (Source: Magyar Onkologia)
Source: Magyar Onkologia - March 14, 2024 Category: Cancer & Oncology Authors: Árpád Kovács Source Type: research
External radiation therapy of primary central nervous system tumors - current trends and practice
Magy Onkol. 2024 Mar 14;68(1):37-50. Epub 2023 Oct 22.ABSTRACTThe family of primary central nervous system (CNS) tumors is a highly heterogeneous group of diseases. In the complex care of CNS tumors, in addition to surgical and systemic treatments, modern external beam radiation therapy (EBRT) plays a prominent role. This summary article provides an overview of the current indications related to EBRT, diagnostic procedures, contouring, planning, and radiation therapy techniques and applications that can be used in daily routine for adults' most common primary CNS tumors.PMID:38484374 (Source: Magyar Onkologia)
Source: Magyar Onkologia - March 14, 2024 Category: Cancer & Oncology Authors: Árpád Kovács Source Type: research
External radiation therapy of primary central nervous system tumors - current trends and practice
Magy Onkol. 2024 Mar 14;68(1):37-50. Epub 2023 Oct 22.ABSTRACTThe family of primary central nervous system (CNS) tumors is a highly heterogeneous group of diseases. In the complex care of CNS tumors, in addition to surgical and systemic treatments, modern external beam radiation therapy (EBRT) plays a prominent role. This summary article provides an overview of the current indications related to EBRT, diagnostic procedures, contouring, planning, and radiation therapy techniques and applications that can be used in daily routine for adults' most common primary CNS tumors.PMID:38484374 (Source: Magyar Onkologia)
Source: Magyar Onkologia - March 14, 2024 Category: Cancer & Oncology Authors: Árpád Kovács Source Type: research
External radiation therapy of primary central nervous system tumors - current trends and practice
Magy Onkol. 2024 Mar 14;68(1):37-50. Epub 2023 Oct 22.ABSTRACTThe family of primary central nervous system (CNS) tumors is a highly heterogeneous group of diseases. In the complex care of CNS tumors, in addition to surgical and systemic treatments, modern external beam radiation therapy (EBRT) plays a prominent role. This summary article provides an overview of the current indications related to EBRT, diagnostic procedures, contouring, planning, and radiation therapy techniques and applications that can be used in daily routine for adults' most common primary CNS tumors.PMID:38484374 (Source: Magyar Onkologia)
Source: Magyar Onkologia - March 14, 2024 Category: Cancer & Oncology Authors: Árpád Kovács Source Type: research
