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Transition of Standard Dosimetry of Absorbed Dose to Water in External Beam Radiotherapy [Part 1]
Igaku Butsuri. 2023;43(4):125-135. doi: 10.11323/jjmp.43.4_125.ABSTRACTThe radiotherapy is performed with the aim of delivering the optimal dose to the target volume with minimal side effect of surrounding normal tissue. For this purpose, quality assurance is essential to ensure that the target volume is correctly irradiated in the optimal geometrical arrangement, and the absorbed dose evaluation is essential to ensure that the prescribed dose is correctly delivered. The absorbed doses are generally evaluated using a small cavity ionization chamber that utilizes gas ionization. For the evaluation of absorbed dose to water ...
Source: Igaku Butsuri: Japanese Journal of Medical Physics - February 28, 2024 Category: Physics Authors: Hidetoshi Saitoh Source Type: research

Practice Patterns of Spatially Fractionated Radiation Therapy: A Clinical Practice Survey
CONCLUSIONS: SFRT has already evolved as a clinical practice pattern for advanced/bulky tumors. Major treatment approaches are consistent and follow the literature, but SFRT-cERT combination/sequencing and clinical utilization of dosimetric parameters are variable. These areas may benefit from targeted education and standardization, and knowledge gaps may be filled by incorporating identified inconsistencies into future clinical research.PMID:38405319 | PMC:PMC10885580 | DOI:10.1016/j.adro.2023.101308 (Source: Cancer Control)
Source: Cancer Control - February 26, 2024 Category: Cancer & Oncology Authors: Nina A Mayr Majid Mohiuddin James W Snider Hualin Zhang Robert J Griffin Beatriz E Amendola Daniel S Hippe Naipy C Perez Xiaodong Wu Simon S Lo William F Regine Charles B Simone Source Type: research

Practice Patterns of Spatially Fractionated Radiation Therapy: A Clinical Practice Survey
CONCLUSIONS: SFRT has already evolved as a clinical practice pattern for advanced/bulky tumors. Major treatment approaches are consistent and follow the literature, but SFRT-cERT combination/sequencing and clinical utilization of dosimetric parameters are variable. These areas may benefit from targeted education and standardization, and knowledge gaps may be filled by incorporating identified inconsistencies into future clinical research.PMID:38405319 | PMC:PMC10885580 | DOI:10.1016/j.adro.2023.101308 (Source: Adv Data)
Source: Adv Data - February 26, 2024 Category: Epidemiology Authors: Nina A Mayr Majid Mohiuddin James W Snider Hualin Zhang Robert J Griffin Beatriz E Amendola Daniel S Hippe Naipy C Perez Xiaodong Wu Simon S Lo William F Regine Charles B Simone Source Type: research

Radiation Therapy Physics Quality Assurance and Management Practices in Low- and Middle-Income Countries: An Initial Pilot Survey in Six Countries and Validation Through a Site Visit
CONCLUSIONS: The preliminary study showed a direct correlation between QA needs and the development index of a country, and the follow-up survey examines operational and physics QA practices in the RT clinics in Ghana, one of the initial countries surveyed. This will form the basis of a planned continent-wide survey in Africa intended to spotlight QA practices in low- and middle-income countries, the challenges faced, and lessons learned to help understand the gaps and needs to support local physics QA and management programs. Audits during the site visit show education and training remain the most important needs in opera...
Source: Adv Data - February 26, 2024 Category: Epidemiology Authors: Afua A Yorke Vonetta M Williams Shekinah Elmore Kellie Alleyne-Mike Eric Addison Philip Oppong Kyeremeh Samuel Nii Adu Tagoe Christoph Jon Trauernicht Graeme L Lazarus Eric C Ford Source Type: research

ONE SHOT - single shot radiotherapy for localized prostate cancer: 18-month results of a single arm, multicenter phase I/II trial
Total dose and dose per fraction play an important role in optimizing the curative treatment of prostate cancer with external beam radiotherapy (EBRT). In the last decade, based on radiobiological modeling showing a low α/β ratio (i.e., ∼ 1.5 Gy) for prostate cancer cells [1], moderate hypofractionated EBRT (i.e., dose per fraction 2.5 Gy to 4 Gy) has largely been adopted in the clinical practice with the attempt to potentially increase the tumor cell killing effect with relatively less toxicity on the su rrounding late responding normal tissues. (Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - February 23, 2024 Category: Radiology Authors: THOMAS ZILLI, CIRO FRANZESE, MATTHIAS GUCKENBERGER, NICCOL Ò GIAJ-LEVRA, NICOLAS MACH, NIKOLAOS KOUTSOUVELIS, VERANE ACHARD, ANDREW MCDONALD, FILIPPO ALONGI, MARTA SCORSETTI, GUILLAUME CONSTANTIN, AURELIE BERTAUT, RAYMOND MIRALBELL Tags: Original Article Source Type: research

Careful Reirradiation
Yes, reirradiation. If the lesions are not in the previous full dose treatment, use available imaging and technology and be mindful of any potential overlap with a reduced external beam radiation therapy (EBRT) dose.1 (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - February 22, 2024 Category: Radiology Authors: Jyoti Mayadev Tags: Gray Zone Source Type: research

Cervical Cancer With Vaginal Recurrence and Prior Pelvic Radiation
A 71-year-old woman with significant medical history of uncontrolled diabetes and multiple myocardial infarctions presented with postmenopausal bleeding and was diagnosed with Federation of Gynecology and Obstetrics stage IIB mesonephric adenocarcinoma of the cervix. The patient proceeded with definitive chemoradiation, 45 Gy in 25 fractions daily external beam radiation to the whole pelvis with concurrent weekly cisplatin, followed by iridium 192 high-dose-rate tandem and ovoid intracavitary brachytherapy boosts, 5.5 Gy for 5 fractions twice weekly to high-risk clinical target volume. (Source: International Journal of Rad...
Source: International Journal of Radiation Oncology * Biology * Physics - February 22, 2024 Category: Radiology Authors: Zeta Chow, Denise Fabian Tags: Gray Zone Source Type: research