Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: Am J Physiol Endocri... - March 27, 2024 Category: Endocrinology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: American Journal of Physiology. Endocrinology and Metabolism - March 27, 2024 Category: Physiology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: Am J Physiol Endocri... - March 27, 2024 Category: Endocrinology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: American Journal of Physiology. Endocrinology and Metabolism - March 27, 2024 Category: Physiology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: Am J Physiol Endocri... - March 27, 2024 Category: Endocrinology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: American Journal of Physiology. Endocrinology and Metabolism - March 27, 2024 Category: Physiology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: Am J Physiol Endocri... - March 27, 2024 Category: Endocrinology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: American Journal of Physiology. Endocrinology and Metabolism - March 27, 2024 Category: Physiology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: Am J Physiol Endocri... - March 27, 2024 Category: Endocrinology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: American Journal of Physiology. Endocrinology and Metabolism - March 27, 2024 Category: Physiology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Effects of Follicle Stimulating Hormone on Energy Balance and Tissue Metabolic Health After Loss of Ovarian Function
Am J Physiol Endocrinol Metab. 2024 Mar 27. doi: 10.1152/ajpendo.00400.2023. Online ahead of print.ABSTRACTLoss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined con...
Source: Am J Physiol Endocri... - March 27, 2024 Category: Endocrinology Authors: Andrew E Libby Claudia Solt Matthew Jackman Vanessa Sherk Rebecca M Foright Ginger C Johnson Thi-Tina Nguyen Matthew Breit Nicholas Hulett Michael Rudolph Paul A Roberson Elizabeth Wellberg Purevsuren Jambal Rebecca L Scalzo Janine Higgins T Rajendra Kuma Source Type: research
Bioinformatics and system biology approach to identify the influences among COVID-19, influenza, and HIV on the regulation of gene expression
ConclusionThis research provides valuable insights into shared molecular targets, signaling pathways, drug chemicals, and potential biomarkers for individuals facing the complex intersection of COVID-19, influenza, and HIV. These findings hold promise for enhancing the precision of diagnosis and treatment for individuals with HIV co-infected with COVID-19 and influenza. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 27, 2024 Category: Allergy & Immunology Source Type: research
A Phase 0/1 Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas
CONCLUSION: Based on safety, brain tumoral PK, and mechanistic data, 15 mg daily is identified as the RP2D for future trials.PMID:38530160 | DOI:10.1158/1078-0432.CCR-23-3341 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - March 26, 2024 Category: Cancer & Oncology Authors: Pankaj B Desai Aniruddha Karve Misam Zawit Priyanka Arora Nimita Dave Joy Awosika Ningjing Li Bethany Fuhrman Mario Medvedovic Larry Sallans Ady Kendler Biplab DasGupta David Plas Richard Curry Mario Zuccarello Rekha Chaudhary Soma Sengupta Trisha M Wise- Source Type: research
Pre ‐diagnostic free androgen and estradiol levels influence heart failure risk in both women and men: A prospective cohort study in the UK Biobank
ConclusionsSex hormones potentially influence HF pathogenesis and may offer pathways for interventions. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - March 26, 2024 Category: Cardiology Authors: Jungeun Lim,
Maryam Hashemian,
Batel Blechter,
V éronique L. Roger,
Jason Y.Y. Wong Tags: Research Article Source Type: research
Effects of injectable contraception with depot medroxyprogesterone acetate or norethisterone enanthate on estradiol levels and menstrual, psychological and behavioral measures relevant to HIV risk: The WHICH randomized trial
by Mandisa Singata-Madliki, Jenni Smit, Mags Beksinska, Yusentha Balakrishna, Chanel Avenant, Ivana Beesham, Ishen Seocharan, Joanne Batting, Janet P. Hapgood, G. Justus Hofmeyr
BackgroundObservational data suggest lower HIV risk with norethisterone enanthate (NET-EN) than with depo-medroxyprogesterone acetate intramuscular (DMPA-IM) injectable contraceptives. If confirmed, a switch between these similar injectable methods would be programmatically feasible and could impact the trajectory of the HIV epidemic. We aimed in this paper to investigate the effects of DMPA-IM and NET-EN on estradiol levels, measures of depression...
Source: PLoS One - March 26, 2024 Category: Biomedical Science Authors: Mandisa Singata-Madliki Source Type: research
