The SARS-CoV-2 Ivermectin Navarra-ISGlobal Trial (SAINT) to Evaluate the Potential of Ivermectin to Reduce COVID-19 Transmission in low risk, non-severe COVID-19 patients in the first 48 hours after symptoms onset: A structured summary of a study protocol for a randomized control pilot trial
AbstractObjectivesThe primary objective is to determine the efficacy of a single dose of ivermectin, administered to low risk, non-severe COVID-19 patients in the first 48 hours after symptom onset to reduce the proportion of patients with detectable SARS-CoV-2 RNA by Polymerase Chain Reaction (PCR) test from nasopharyngeal swab at day 7 post-treatment.The secondary objectives are:To assess the efficacy of ivermectin to reduce the SARS-CoV-2 viral load in the nasopharyngeal swab at day 7 post treatment.To assess the efficacy of ivermectin to improve symptom progression in treated patients.To assess the proportion of seroco...
Source: Trials - June 7, 2020 Category: Research Source Type: clinical trials

Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea
Condition:   Malaria Interventions:   Biological: PfSPZ Vaccine;   Other: Normal saline;   Biological: PfSPZ Challenge (for CHMI) Sponsors:   Sanaria Inc.;   Ifakara Health Institute;   Swiss Tropical & Public Health Institute;   Government of Equatorial Guinea;   Noble Oil Services;   Marathon Oil Corporation;   Atlantic Methanol Production Company;   Equatorial Guinea (EG) liquefied natural gas (LNG) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 18, 2018 Category: Research Source Type: clinical trials

Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea.
Condition:   Malaria Interventions:   Biological: PfSPZ Vaccine;   Biological: PfSPZ Challenge (for CHMI);   Other: Normal Saline;   Biological: PfSPZ Challenge (for PfSPZ-CVac) Sponsors:   Sanaria Inc.;   Ifakara Health Institute;   Swiss Tropical & Public Health Institute;   Government of Equatorial Guinea;   Marathon Oil Corporation;   Noble Oil Services;   La Paz Medical Center, Malabo, Equatorial Guinea Not yet recruiting - verified August 2016 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 27, 2016 Category: Research Source Type: clinical trials