Fight Aging! Newsletter, April 15th 2024
In conclusion, although several clinical trials targeting SnCs are ongoing, various questions about the biology of SnCs remain open, resulting in a gap between molecular and cellular data. Concerning the need, initiatives such as SenNet aiming to create openly accessible atlases of SnCs should contribute enormously to the area. Advances in understanding the subcellular structure, the heterogeneity, and the dynamics of SnCs require the integration of molecular and cellular techniques with data analysis packages to evaluate high throughput evidence from microscopy and flow cytometry. It is also necessary to develop new equip...
Source: Fight Aging! - April 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Novel mTOR Inhibitors Viewed as a Safer Option by Conservative Investors
The safest sort of investment into therapeutic development is one made in a part of a field that is well established, producing a small variant of an existing drug, using the well beaten path of small molecule development, targeting a mechanism that is very well understood, and that has extensive safety data associated with it. One could argue that mTOR inhibition is the canonical example of a low risk investment in the longevity field. Like most lower-risk exercises in medical development, the potential gain for patients is modest. mTOR inhibition can produce larger gains in mouse life span than exercise, but doesn't beat...
Source: Fight Aging! - April 8, 2024 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs
The Most Overhyped Technologies in Healthcare
The hype about technological development in healthcare should not blind us in terms of the probabilities and possibilities of today’s healthcare and the future of medicine. To remain objective and conscious but still optimistic, let’s look at the most overhyped technologies and keep in mind the realistic development opportunities in healing.
You know the saying: the pessimist says the glass is half empty, the optimist says it is half full, and, well, the cynic asks who drank the other half? I’m truly an optimist – especially when it comes to the future of medicine and healthcare, but we need to ask the uncom...
Source: The Medical Futurist - December 5, 2023 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine 3d printing robotics virtual reality wearables GC1 hype organs Source Type: blogs
Will We All Have To Become Biologically Enhanced Superhumans?
Okay, hands up who can tell who’s the most famous biologically enhanced superhuman in the world? True, it’s a quite close call between Captain America and The Incredible Hulk (sorry Spidey, you’re not even close). But are human-invented superhumans just a thing of a Stan Lee comic, or is it an actual scientific idea from a real laboratory?
As a matter of fact, enhancing human capabilities has been on the minds of people for ages, but it has come a long way from ancient training methods to exoskeletons. Enhancing our abilities, be it permanently or temporarily is a tempting but risky matter. Will it be possibl...
Source: The Medical Futurist - November 21, 2023 Category: Information Technology Authors: berci.mesko Tags: Forecast Artificial Intelligence in Medicine Augmented Reality Bioethics Biotechnology Cyborgization Digital Health Research E-Patients Genomics Health Sensors & Trackers Healthcare Policy Medical Education Robotics Science Ficti Source Type: blogs
Bonus Features – September 10, 2023 – 77% of clinicians see RPM outpacing traditional inpatient care within five years, Microsoft partnering with Paige on pathology and oncology AI models, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News
Executives for Healthcare Innovation is transferring its assets to the American Telemedicine Association, and ATA will extend engagement opportunities to current EHI members through its various Special Interest Groups.
More...
Source: EMR and HIPAA - September 11, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Adrian Agostini Alo American Telemedicine Association Andrea Rowe Anki ATA AVIA Black Book Research Canopy Edifecs Experity Healthcare IT Today Bonus Features HITRUST Ibex Medical Analytics iMerit Inovalon K Source Type: blogs
Pump Up the Potassium
The element potassium plays a pivotal role in our bodies. It’s found in all our cells, where it regulates their volume and pressure. To do this, our bodies carefully control potassium levels so that the concentration is about 30 times higher inside cells than outside. Potassium works closely with sodium, which regulates the extracellular fluid volume and has a higher concentration outside cells than inside. These concentration differences create an electrochemical gradient, or a membrane potential.
Potassium is the primary regulator of the pressure and volume inside cells, and it’s important for nerve transmiss...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 21, 2023 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Molecular Structures Cellular Processes Element Proteins Source Type: blogs
Soft Robotic Electrode Enables Minimally Invasive Placement
Researchers at Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland have developed a soft robotic electrode, that can be advanced through a small hole in the skull and then opened into a series of spiral arms, to provide electrocorticography measurements from a relatively large area of the brain surface. The technology could prove very useful for brain surgeons who wish to map regions of the brain that may be triggering epileptic seizures and then target these lesions surgically. Reducing the area of the skull that is removed during surgery helps to speed patient recovery and reduce the trauma associated with s...
Source: Medgadget - May 23, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials Neurology Neurosurgery EPFL Source Type: blogs
Using Technology to Address Medication Access
In conclusion, the market for medications in the United States is broad, confusing, and often arbitrary.
Information gaps open the market to manipulative direct-to-consumer advertising by pharmaceutical companies. Perhaps the services described in this article could undermine the appeal for drugs that appear on major TV channels. If you’re told that the premium medication you’ve been sold on TV is essentially no better than a generic, you can save yourself and your insurer a lot of money.
It’s daunting to pull together all the public sources of help, but well-designed technology can do it fast enough to h...
Source: EMR and HIPAA - April 3, 2023 Category: Information Technology Authors: Andy Oram Tags: Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System LTPAC AdhereHealth athenahealth Babylon Health Cognizant Colin Banas DrFirst Medication Access Source Type: blogs
ChatGPT in conversation with a language scientist (Hickok)
Some interesting failures in this conversation with ChatGPT, not just about the facts of language& brain but some glaring logical failures, like that people with complete damage to Wernicke ' s area would perform significantly worse than chance on a test of word comprehension. On questioning, it impressively " recognized " the error but then the bug re-emerged on the very last question.---------------------Which of the following is true about the neural basis of speech perception? a) it ' s bilateral in the STG. b) it ' s strongly left hemisphere dominant. c) it is dependent on Broca ' s area. d) it is the ability to p...
Source: Talking Brains - March 17, 2023 Category: Neuroscience Authors: Greg Hickok Source Type: blogs
Neural Chip Detects, Suppresses Neurological Symptoms
Researchers at Ecole Polytechnique Fédérale de Lausanne in Switzerland have designed an advanced neural chip that can detect and suppress symptoms from a variety of neurological disorders, including Parkinson’s and epilepsy. The closed-loop neuromodulation system, which the researchers have called NeuralTree, includes soft implantable electrodes, a processor for machine learning, and a 256 channel sensing array. The device is also energy efficient, helping to extend battery life. The technology can spot the signs of upcoming tremors or seizures, for example, and initiate neurostimulation to reduce or avoid the symptoms...
Source: Medgadget - February 7, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Neurology Neurosurgery brain computer interface EPFL Source Type: blogs
This patient did not present with chest pain
This was posted a few years ago. I ' m highlighting it again, with comments from Ken Grauer below.This was sent to me by Jason Winter. @JasonWinterECGThis is a 36 yo m with h/o TBI and epilepsy. He had a seizure this morning and rolled out of bed unable to get up. There were no injuries and no chest pain and he appeared well. He complained of 3 days of diarrhea and abdominal pain. The medics recorded a prehospital ECG: The computerized QTc is 397 msJason writes: "What ' s your thoughts Steve? "Jason was very skeptical of STEMI.What do you think?Jason,I agree.V4 especially looks li...
Source: Dr. Smith's ECG Blog - February 4, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs
Neuroscience Trend Forecasters
As 2022 draws to a close, the SNL Trend Forecasters have agreed to divulge their predictions for the most — and the least— exciting research fads for the New Year.The Neurocritic: How do you guys predict today ' s most popular neuroscience trends? Trend Forecasters: Oh, well we have 4,000 computers, they ' re all big they all make charts and they beep LOUD.TN: Let ' s get started!In:posterior cingulate cortexHey Posterior Cingulate — we see you! You ' re fresh, you ' re mysterious, you ' re misunderstood. But we know you exist far beyond the default fashion mode. Thenew tripartite view proposes......that the bro...
Source: The Neurocritic - December 31, 2022 Category: Neuroscience Authors: The Neurocritic Source Type: blogs
Disordered activity? A review of the quality of epilepsy care provided to adult patients presenting to hospital with a seizure
National Confidential Enquiry into Patient Outcome and Death (NCEPOD) - Data from 610 clinical questionnaires, 264 sets of case notes and 158 organisational questionnaires were used to assess the quality of care provided to adult patients with a pre-existing epilepsy disorder or who were subsequently diagnosed with epilepsy and presented to hospital following a seizure, between 1st January and 31st December 2020.ReportMore detail (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - December 12, 2022 Category: UK Health Authors: The King ' s Fund Library Tags: NHS performance and productivity Source Type: blogs
Depression: The Highway to Success Has an Awful Lot of Detours
I’ll write a bit vaguely today because I want to touch upon some things that are family matters and how they impact me.Recently, I have noticed longtime readers of my blog have leapfrogged over me while my life has become stagnant. I caught myself beginning to feel bitter about it, so instead of letting that bitterness settle into depression, I will share some things that I have learned instead.My life took a detour a few years back, if eleven can be called of few. It was as if I was forced to take an exit and found myself on the service road bumping along besides the highway, falling behind all the other traffic. I ...
Source: The Splintered Mind by Douglas Cootey - November 4, 2022 Category: Psychiatry Tags: ADHD Depression Family Goodreads Journaling Post-COVID Source Type: blogs
" And then a Plank in Reason, broke, "
“I am dead.” In terms of possible delusions in living human beings,Le d élire des négations—the nihilistic delusion that one is dead —evokes the most harrowing existence imaginable. The French neurologistJules Cotard first described the syndrome that bears his name (1882,English translation):I hazard the name ofdelirium of negations to designate the state of the patients ... in whom the negative disposition is carried to the highest degree. [They are] asked their name – they have no name; their age – they are ageless; where were they born – they were not born; ... if they have a headache, s...
Source: The Neurocritic - September 30, 2022 Category: Neuroscience Authors: The Neurocritic Source Type: blogs
