MicroRNA Expression in Endometrial Cancer: Current Knowledge and Therapeutic Implications
Conclusions: Although their epigenetic regulation remains unknown, these upregulated molecules derived from EVs are feasible markers for the early detection of endometrial cancer. The modulation of these miRNA molecules should be assessed during different treatments or if recurrence develops in response to a targeted treatment modality.PMID:38541212 | PMC:PMC10972089 | DOI:10.3390/medicina60030486 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Irene Iavarone Rossella Molitierno Pietro Fumiento Maria Giovanna Vastarella Stefania Napolitano Maria Teresa Vietri Pasquale De Franciscis Carlo Ronsini Source Type: research
MicroRNA Expression in Endometrial Cancer: Current Knowledge and Therapeutic Implications
Conclusions: Although their epigenetic regulation remains unknown, these upregulated molecules derived from EVs are feasible markers for the early detection of endometrial cancer. The modulation of these miRNA molecules should be assessed during different treatments or if recurrence develops in response to a targeted treatment modality.PMID:38541212 | PMC:PMC10972089 | DOI:10.3390/medicina60030486 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Irene Iavarone Rossella Molitierno Pietro Fumiento Maria Giovanna Vastarella Stefania Napolitano Maria Teresa Vietri Pasquale De Franciscis Carlo Ronsini Source Type: research
Cancers, Vol. 16, Pages 1315: Detection and Classification of Hysteroscopic Images Using Deep Learning
Conclusion: Our DL model achieved a low diagnostic performance in the detection and classification of intracavitary uterine lesions from hysteroscopic images. Although the best diagnostic performance was obtained with the aid of clinical data, such an improvement was slight. (Source: Cancers)
Source: Cancers - March 28, 2024 Category: Cancer & Oncology Authors: Diego Raimondo Antonio Raffone Paolo Salucci Ivano Raimondo Giampiero Capobianco Federico Andrea Galatolo Mario Giovanni Cosimo Antonio Cimino Antonio Travaglino Manuela Maletta Stefano Ferla Agnese Virgilio Daniele Neola Paolo Casadio Renato Seracchioli Tags: Article Source Type: research
Treatment outcomes according to various progestin treatment strategies in patients with atypical hyperplasia/endometrial intraepithelial neoplasia - Multicenter retrospective study (KGOG2033)
CONCLUSIONS: Although OP alone achieved more short-term pCR than the other groups, more recurrences occurred after pCR than LNG-IUD alone. High-dose OP as well as combination of OP and LNG-IUD did not increase pCR or reduce recurrence. Maintenance therapy may reduce the recurrence rate after pCR.PMID:38520881 | DOI:10.1016/j.ygyno.2024.03.017 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 23, 2024 Category: Cancer & Oncology Authors: Nam Kyeong Kim Chel Hun Choi Seok Ju Seong Jong-Min Lee Banghyun Lee Kidong Kim Source Type: research
Treatment outcomes according to various progestin treatment strategies in patients with atypical hyperplasia/endometrial intraepithelial neoplasia - Multicenter retrospective study (KGOG2033)
CONCLUSIONS: Although OP alone achieved more short-term pCR than the other groups, more recurrences occurred after pCR than LNG-IUD alone. High-dose OP as well as combination of OP and LNG-IUD did not increase pCR or reduce recurrence. Maintenance therapy may reduce the recurrence rate after pCR.PMID:38520881 | DOI:10.1016/j.ygyno.2024.03.017 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 23, 2024 Category: Cancer & Oncology Authors: Nam Kyeong Kim Chel Hun Choi Seok Ju Seong Jong-Min Lee Banghyun Lee Kidong Kim Source Type: research
Treatment outcomes according to various progestin treatment strategies in patients with atypical hyperplasia/endometrial intraepithelial neoplasia - Multicenter retrospective study (KGOG2033)
CONCLUSIONS: Although OP alone achieved more short-term pCR than the other groups, more recurrences occurred after pCR than LNG-IUD alone. High-dose OP as well as combination of OP and LNG-IUD did not increase pCR or reduce recurrence. Maintenance therapy may reduce the recurrence rate after pCR.PMID:38520881 | DOI:10.1016/j.ygyno.2024.03.017 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 23, 2024 Category: Cancer & Oncology Authors: Nam Kyeong Kim Chel Hun Choi Seok Ju Seong Jong-Min Lee Banghyun Lee Kidong Kim Source Type: research
Treatment outcomes according to various progestin treatment strategies in patients with atypical hyperplasia/endometrial intraepithelial neoplasia - Multicenter retrospective study (KGOG2033)
CONCLUSIONS: Although OP alone achieved more short-term pCR than the other groups, more recurrences occurred after pCR than LNG-IUD alone. High-dose OP as well as combination of OP and LNG-IUD did not increase pCR or reduce recurrence. Maintenance therapy may reduce the recurrence rate after pCR.PMID:38520881 | DOI:10.1016/j.ygyno.2024.03.017 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 23, 2024 Category: Cancer & Oncology Authors: Nam Kyeong Kim Chel Hun Choi Seok Ju Seong Jong-Min Lee Banghyun Lee Kidong Kim Source Type: research
Treatment outcomes according to various progestin treatment strategies in patients with atypical hyperplasia/endometrial intraepithelial neoplasia - Multicenter retrospective study (KGOG2033)
CONCLUSIONS: Although OP alone achieved more short-term pCR than the other groups, more recurrences occurred after pCR than LNG-IUD alone. High-dose OP as well as combination of OP and LNG-IUD did not increase pCR or reduce recurrence. Maintenance therapy may reduce the recurrence rate after pCR.PMID:38520881 | DOI:10.1016/j.ygyno.2024.03.017 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 23, 2024 Category: Cancer & Oncology Authors: Nam Kyeong Kim Chel Hun Choi Seok Ju Seong Jong-Min Lee Banghyun Lee Kidong Kim Source Type: research
Treatment outcomes according to various progestin treatment strategies in patients with atypical hyperplasia/endometrial intraepithelial neoplasia - Multicenter retrospective study (KGOG2033)
CONCLUSIONS: Although OP alone achieved more short-term pCR than the other groups, more recurrences occurred after pCR than LNG-IUD alone. High-dose OP as well as combination of OP and LNG-IUD did not increase pCR or reduce recurrence. Maintenance therapy may reduce the recurrence rate after pCR.PMID:38520881 | DOI:10.1016/j.ygyno.2024.03.017 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 23, 2024 Category: Cancer & Oncology Authors: Nam Kyeong Kim Chel Hun Choi Seok Ju Seong Jong-Min Lee Banghyun Lee Kidong Kim Source Type: research
The endometrial transcriptome of infertile women with and without implantation failure
ConclusionsNo distinct endometrial transcriptome profile was associated with either implantation failure or success in infertile women. However, there may be differences in the extent to which the WOI is displaced. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - March 23, 2024 Category: OBGYN Authors: Bich Ngoc Bui,
Viktorija Kukushkina,
Alvin Meltsov,
Catharina Olsen,
Nienke van Hoogenhuijze,
Signe Altm äe,
Femke Mol,
Gijs Teklenburg,
Jan‐Peter de Bruin,
Dagmar Besselink,
Linda Stevens Brentjens,
Darina Obukhova,
Masoud Zamani Esteki, Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Analysis of clinical data of different endometrial pathological types in perimenopausal women with abnormal uterine bleeding
ConclusionsThe most common cause of perimenopausal women with AUB was benign endometrial lesions. However, women aged 51–55 years old with endometrial high risk factors and ovarian cyst should be alert to AEH and EC. Endometrial biopsy needs to be performed to determine endometrial malignancy in necessity. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - February 29, 2024 Category: Cancer & Oncology Source Type: research
The Role of Lymphovascular Space Invasion and Cytology in the Prognosis of Endometrial Cancer
CONCLUSIONS: In our study, we observed that LVSI positivity and cytology positivity also reduced the overall survival rate. We aimed to highlight that, in addition to molecular classification, cytology positivity and LVSI positivity are still highly significant and independent factors in prognosis.PMID:38409841 | DOI:10.24976/Discov.Med.202436181.34 (Source: Discovery Medicine)
Source: Discovery Medicine - February 27, 2024 Category: Research Authors: Cem Yagmur Ozdemir Dagistan Tolga Arioz Fatih Celik Nayif Cicekli Mariam Chkhikvadze Filiz Bilir Sezgin Y ılmaz Nefize Vatansever Source Type: research
