Novel Performance Rating Instruments for Gynecological Procedures in Primary Care: A Pilot Study
CONCLUSIONS: We developed novel performance rating instruments for four gynecological procedures and provided preliminary validity evidence for their use for formative feedback in a simulation setting. This pilot study suggests that these instruments may facilitate the training and documentation of family medicine trainees' skills in gynecological procedures.PMID:37725774 | DOI:10.22454/FamMed.2023.261011 (Source: Family Medicine)
Source: Family Medicine - September 19, 2023 Category: Primary Care Authors: Parisa Rezaiefar Nisha Waqas Douglas Archibald Susan Humphrey Murto Source Type: research

Novel Performance Rating Instruments for Gynecological Procedures in Primary Care: A Pilot Study
CONCLUSIONS: We developed novel performance rating instruments for four gynecological procedures and provided preliminary validity evidence for their use for formative feedback in a simulation setting. This pilot study suggests that these instruments may facilitate the training and documentation of family medicine trainees' skills in gynecological procedures.PMID:37725774 | DOI:10.22454/FamMed.2023.261011 (Source: Famly Medicine)
Source: Famly Medicine - September 19, 2023 Category: Primary Care Authors: Parisa Rezaiefar Nisha Waqas Douglas Archibald Susan Humphrey Murto Source Type: research

Novel Performance Rating Instruments for Gynecological Procedures in Primary Care: A Pilot Study
CONCLUSIONS: We developed novel performance rating instruments for four gynecological procedures and provided preliminary validity evidence for their use for formative feedback in a simulation setting. This pilot study suggests that these instruments may facilitate the training and documentation of family medicine trainees' skills in gynecological procedures.PMID:37725774 | DOI:10.22454/FamMed.2023.261011 (Source: Family Medicine)
Source: Family Medicine - September 19, 2023 Category: Primary Care Authors: Parisa Rezaiefar Nisha Waqas Douglas Archibald Susan Humphrey Murto Source Type: research

Novel Performance Rating Instruments for Gynecological Procedures in Primary Care: A Pilot Study
CONCLUSIONS: We developed novel performance rating instruments for four gynecological procedures and provided preliminary validity evidence for their use for formative feedback in a simulation setting. This pilot study suggests that these instruments may facilitate the training and documentation of family medicine trainees' skills in gynecological procedures.PMID:37725774 | DOI:10.22454/FamMed.2023.261011 (Source: Famly Medicine)
Source: Famly Medicine - September 19, 2023 Category: Primary Care Authors: Parisa Rezaiefar Nisha Waqas Douglas Archibald Susan Humphrey Murto Source Type: research

Deciphering a shared transcriptomic regulation and the relative contribution of each regulator type through endometrial gene expression signatures
CONCLUSIONS: This study revealed novel hormonal and non-hormonal regulators and their relative contributions to endometrial progression and pathology, providing new leads for the potential causes of endometrial-factor infertility.PMID:37700285 | DOI:10.1186/s12958-023-01131-4 (Source: Reproductive Biology)
Source: Reproductive Biology - September 12, 2023 Category: Reproduction Medicine Authors: Antonio Parraga-Leo Patricia Sebastian-Leon Almudena Devesa-Peiro Diana Marti-Garcia Nuria Pellicer Jose Remohi Francisco Dominguez Patricia Diaz-Gimeno Source Type: research

Risk of endometrial polyp and surgical intervention in postmenopausal women with proliferative endometrium
Endometrial biopsy (EMB) is commonly performed in postmenopausal women to exclude endometrial cancer or hyperplasia (ECH) [1]. Most EMB results are benign; while the majority will have atrophic endometrium (AE), about 15  % are found to have proliferative endometrium (PE) [2–7]. The long-term clinical significance of the various benign endometrial histologies is poorly understood. PE histology includes formation of tubular glands, tall pseudostratified columnar cells and mitotic figures and has been associated w ith obesity. (Source: Maturitas)
Source: Maturitas - September 9, 2023 Category: Primary Care Authors: Ohad Rotenberg, Georgios Doulaveris, Dmitry Fridman, Malte Renz, Julie Kaplan, Xianhong Xie, Gary L. Goldberg, Pe'er Dar Tags: Original article Source Type: research

GSE234434 A novel molecular staging model for accurately dating the endometrial biopsy
Series Type : Expression profiling by array ; Expression profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - September 6, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by array Expression profiling by high throughput sequencing Homo sapiens Source Type: research

GSE234354 A novel molecular staging model for accurately dating the endometrial biopsy [RNA-seq]
Contributors : Peter A Rogers ; Jessica Chung ; Wan T Teh ; Sally Mortlock ; Jenny N Fung ; Grant W MontgomerySeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensNatural variability in menstrual cycle length, coupled with rapid changes in endometrial gene expression, makes it difficult to accurately define and compare different stages of the endometrial cycle. We have developed and validated a novel method for precisely determining endometrial cycle stage based on global gene expression. Our ‘molecular staging model’ reveals significant and remarkably synchronized daily changes in e...
Source: GEO: Gene Expression Omnibus - September 6, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Isolated Tumor Cells in Sentinel Lymph Nodes: Does It Really Matter?
A 57-year-old woman with no significant medical history presented with postmenopausal bleeding. An endometrial biopsy was consistent with endometrial adenocarcinoma, endometrioid type with squamous differentiation, Federation of Gynecology and Obstetrics (FIGO) grade 1. The patient proceeded to robotic-assisted hysterectomy, bilateral salpingo-oophorectomy, and sentinel lymph node sampling. Surgical pathology again revealed endometrioid adenocarcinoma, FIGO grade 1, measuring 4 cm in greatest dimension, with a myometrial invasion of 6 mm out of 13 mm (46%). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - August 29, 2023 Category: Radiology Authors: Jianling Yuan, Susan Y. Sun Tags: Gray Zone Source Type: research

Characteristic of Endometrial Stromal Sarcoma by Algorithm of Potential Biomarkers for Uterine Mesenchymal Tumor
Curr Issues Mol Biol. 2023 Jul 25;45(8):6190-6201. doi: 10.3390/cimb45080390.ABSTRACTThe benign tumor uterine leiomyoma (UL) develops from the smooth muscle tissue that constitutes the uterus, whereas malignant tumor uterine sarcoma develops from either the smooth muscle tissue or stroma and is different from UL and endometrial cancer. Uterine sarcoma is broadly classified into three types: uterine leiomyosarcoma, endometrial stromal sarcoma (ESS), and carcinosarcoma. Although uterine leiomyosarcoma and ESS are both classified as uterine sarcoma, they significantly differ in terms of their sites of occurrence, symptoms, an...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Takuma Hayashi Kenji Sano Nobuo Yaegashi Kaoru Abiko Ikuo Konishi Source Type: research

Characteristic of Endometrial Stromal Sarcoma by Algorithm of Potential Biomarkers for Uterine Mesenchymal Tumor
Curr Issues Mol Biol. 2023 Jul 25;45(8):6190-6201. doi: 10.3390/cimb45080390.ABSTRACTThe benign tumor uterine leiomyoma (UL) develops from the smooth muscle tissue that constitutes the uterus, whereas malignant tumor uterine sarcoma develops from either the smooth muscle tissue or stroma and is different from UL and endometrial cancer. Uterine sarcoma is broadly classified into three types: uterine leiomyosarcoma, endometrial stromal sarcoma (ESS), and carcinosarcoma. Although uterine leiomyosarcoma and ESS are both classified as uterine sarcoma, they significantly differ in terms of their sites of occurrence, symptoms, an...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Takuma Hayashi Kenji Sano Nobuo Yaegashi Kaoru Abiko Ikuo Konishi Source Type: research

Characteristic of Endometrial Stromal Sarcoma by Algorithm of Potential Biomarkers for Uterine Mesenchymal Tumor
Curr Issues Mol Biol. 2023 Jul 25;45(8):6190-6201. doi: 10.3390/cimb45080390.ABSTRACTThe benign tumor uterine leiomyoma (UL) develops from the smooth muscle tissue that constitutes the uterus, whereas malignant tumor uterine sarcoma develops from either the smooth muscle tissue or stroma and is different from UL and endometrial cancer. Uterine sarcoma is broadly classified into three types: uterine leiomyosarcoma, endometrial stromal sarcoma (ESS), and carcinosarcoma. Although uterine leiomyosarcoma and ESS are both classified as uterine sarcoma, they significantly differ in terms of their sites of occurrence, symptoms, an...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Takuma Hayashi Kenji Sano Nobuo Yaegashi Kaoru Abiko Ikuo Konishi Source Type: research

Characteristic of Endometrial Stromal Sarcoma by Algorithm of Potential Biomarkers for Uterine Mesenchymal Tumor
Curr Issues Mol Biol. 2023 Jul 25;45(8):6190-6201. doi: 10.3390/cimb45080390.ABSTRACTThe benign tumor uterine leiomyoma (UL) develops from the smooth muscle tissue that constitutes the uterus, whereas malignant tumor uterine sarcoma develops from either the smooth muscle tissue or stroma and is different from UL and endometrial cancer. Uterine sarcoma is broadly classified into three types: uterine leiomyosarcoma, endometrial stromal sarcoma (ESS), and carcinosarcoma. Although uterine leiomyosarcoma and ESS are both classified as uterine sarcoma, they significantly differ in terms of their sites of occurrence, symptoms, an...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Takuma Hayashi Kenji Sano Nobuo Yaegashi Kaoru Abiko Ikuo Konishi Source Type: research

Characteristic of Endometrial Stromal Sarcoma by Algorithm of Potential Biomarkers for Uterine Mesenchymal Tumor
Curr Issues Mol Biol. 2023 Jul 25;45(8):6190-6201. doi: 10.3390/cimb45080390.ABSTRACTThe benign tumor uterine leiomyoma (UL) develops from the smooth muscle tissue that constitutes the uterus, whereas malignant tumor uterine sarcoma develops from either the smooth muscle tissue or stroma and is different from UL and endometrial cancer. Uterine sarcoma is broadly classified into three types: uterine leiomyosarcoma, endometrial stromal sarcoma (ESS), and carcinosarcoma. Although uterine leiomyosarcoma and ESS are both classified as uterine sarcoma, they significantly differ in terms of their sites of occurrence, symptoms, an...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Takuma Hayashi Kenji Sano Nobuo Yaegashi Kaoru Abiko Ikuo Konishi Source Type: research

Characteristic of Endometrial Stromal Sarcoma by Algorithm of Potential Biomarkers for Uterine Mesenchymal Tumor
Curr Issues Mol Biol. 2023 Jul 25;45(8):6190-6201. doi: 10.3390/cimb45080390.ABSTRACTThe benign tumor uterine leiomyoma (UL) develops from the smooth muscle tissue that constitutes the uterus, whereas malignant tumor uterine sarcoma develops from either the smooth muscle tissue or stroma and is different from UL and endometrial cancer. Uterine sarcoma is broadly classified into three types: uterine leiomyosarcoma, endometrial stromal sarcoma (ESS), and carcinosarcoma. Although uterine leiomyosarcoma and ESS are both classified as uterine sarcoma, they significantly differ in terms of their sites of occurrence, symptoms, an...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Takuma Hayashi Kenji Sano Nobuo Yaegashi Kaoru Abiko Ikuo Konishi Source Type: research