Severe Disulfiram or Antabuse Reactions
‚ÄčAlcoholism has been treated with disulfiram (Antabuse) ever since the drug received FDA approval in 1951. Disulfiram is one of a number of medications that produces unwanted side effects caused by the accumulation of acetaldehyde when taken with alcohol.‚ÄčThe story behind the discovery of disulfiram is typical of serendipitous observations. A physician noted in 1937 that workers in the rubber industry exposed to disulfiram developed a reaction after drinking alcohol. Several decades later, two Danish researchers evaluating disulfiram as an antihelminthic developed symptoms after attending a cocktail party. (Medscape, J...
Source: M2E Too! Mellick's Multimedia EduBlog - June 1, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs