Do people with ME/CFS and joint hypermobility represent a disease subgroup? An analysis using registry data
ConclusionME/CFS patients with joint hypermobility, particularly those with EDS, demonstrate distinct clinical characteristics, including more severe symptomatology and reduced HRQOL. These findings highlight the need for comprehensive clinical assessments of ME/CFS patients with joint hypermobility. Understanding these relationships could aid in subgroup identification, improving diagnosis, and informing targeted therapeutic approaches. Further research is warranted to explore these associations and their implications for clinical practice. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 13, 2024 Category: Neurology Source Type: research

Heavy Menstrual Bleeding in Adolescents with Joint Hypermobility Syndrome/Hypermobile-Type Ehlers-Danlos: A Review
Pediatr Ann. 2024 Mar;53(3):e104-e108. doi: 10.3928/19382359-20240109-05. Epub 2024 Mar 1.ABSTRACTHeavy menstrual bleeding has a high prevalence and is well documented in adult patients with hypermobile-type Ehlers-Danlos syndrome, but there is limited research surrounding work-up and treatment for the adolescent population. Excessive menstrual blood loss can significantly interfere with emotional and physical quality of life. A provider should acquire a comprehensive medical and menstrual history and focused physical examination, as well as baseline laboratory studies, to determine the presence of anemia or underlying ble...
Source: Pediatric Annals - March 11, 2024 Category: Pediatrics Authors: Erin Isaacson Tazim Dowlut-McElroy Source Type: research

Heavy Menstrual Bleeding in Adolescents with Joint Hypermobility Syndrome/Hypermobile-Type Ehlers-Danlos: A Review
Pediatr Ann. 2024 Mar;53(3):e104-e108. doi: 10.3928/19382359-20240109-05. Epub 2024 Mar 1.ABSTRACTHeavy menstrual bleeding has a high prevalence and is well documented in adult patients with hypermobile-type Ehlers-Danlos syndrome, but there is limited research surrounding work-up and treatment for the adolescent population. Excessive menstrual blood loss can significantly interfere with emotional and physical quality of life. A provider should acquire a comprehensive medical and menstrual history and focused physical examination, as well as baseline laboratory studies, to determine the presence of anemia or underlying ble...
Source: Pediatric Annals - March 11, 2024 Category: Pediatrics Authors: Erin Isaacson Tazim Dowlut-McElroy Source Type: research

Heavy Menstrual Bleeding in Adolescents with Joint Hypermobility Syndrome/Hypermobile-Type Ehlers-Danlos: A Review
Pediatr Ann. 2024 Mar;53(3):e104-e108. doi: 10.3928/19382359-20240109-05. Epub 2024 Mar 1.ABSTRACTHeavy menstrual bleeding has a high prevalence and is well documented in adult patients with hypermobile-type Ehlers-Danlos syndrome, but there is limited research surrounding work-up and treatment for the adolescent population. Excessive menstrual blood loss can significantly interfere with emotional and physical quality of life. A provider should acquire a comprehensive medical and menstrual history and focused physical examination, as well as baseline laboratory studies, to determine the presence of anemia or underlying ble...
Source: Pediatric Annals - March 11, 2024 Category: Pediatrics Authors: Erin Isaacson Tazim Dowlut-McElroy Source Type: research

Heavy Menstrual Bleeding in Adolescents with Joint Hypermobility Syndrome/Hypermobile-Type Ehlers-Danlos: A Review
Pediatr Ann. 2024 Mar;53(3):e104-e108. doi: 10.3928/19382359-20240109-05. Epub 2024 Mar 1.ABSTRACTHeavy menstrual bleeding has a high prevalence and is well documented in adult patients with hypermobile-type Ehlers-Danlos syndrome, but there is limited research surrounding work-up and treatment for the adolescent population. Excessive menstrual blood loss can significantly interfere with emotional and physical quality of life. A provider should acquire a comprehensive medical and menstrual history and focused physical examination, as well as baseline laboratory studies, to determine the presence of anemia or underlying ble...
Source: Pediatric Annals - March 11, 2024 Category: Pediatrics Authors: Erin Isaacson Tazim Dowlut-McElroy Source Type: research

Heavy Menstrual Bleeding in Adolescents with Joint Hypermobility Syndrome/Hypermobile-Type Ehlers-Danlos: A Review
Pediatr Ann. 2024 Mar;53(3):e104-e108. doi: 10.3928/19382359-20240109-05. Epub 2024 Mar 1.ABSTRACTHeavy menstrual bleeding has a high prevalence and is well documented in adult patients with hypermobile-type Ehlers-Danlos syndrome, but there is limited research surrounding work-up and treatment for the adolescent population. Excessive menstrual blood loss can significantly interfere with emotional and physical quality of life. A provider should acquire a comprehensive medical and menstrual history and focused physical examination, as well as baseline laboratory studies, to determine the presence of anemia or underlying ble...
Source: Pediatric Annals - March 11, 2024 Category: Pediatrics Authors: Erin Isaacson Tazim Dowlut-McElroy Source Type: research

Heavy Menstrual Bleeding in Adolescents with Joint Hypermobility Syndrome/Hypermobile-Type Ehlers-Danlos: A Review
Pediatr Ann. 2024 Mar;53(3):e104-e108. doi: 10.3928/19382359-20240109-05. Epub 2024 Mar 1.ABSTRACTHeavy menstrual bleeding has a high prevalence and is well documented in adult patients with hypermobile-type Ehlers-Danlos syndrome, but there is limited research surrounding work-up and treatment for the adolescent population. Excessive menstrual blood loss can significantly interfere with emotional and physical quality of life. A provider should acquire a comprehensive medical and menstrual history and focused physical examination, as well as baseline laboratory studies, to determine the presence of anemia or underlying ble...
Source: Pediatric Annals - March 11, 2024 Category: Pediatrics Authors: Erin Isaacson Tazim Dowlut-McElroy Source Type: research

Heavy Menstrual Bleeding in Adolescents with Joint Hypermobility Syndrome/Hypermobile-Type Ehlers-Danlos: A Review
Pediatr Ann. 2024 Mar;53(3):e104-e108. doi: 10.3928/19382359-20240109-05. Epub 2024 Mar 1.ABSTRACTHeavy menstrual bleeding has a high prevalence and is well documented in adult patients with hypermobile-type Ehlers-Danlos syndrome, but there is limited research surrounding work-up and treatment for the adolescent population. Excessive menstrual blood loss can significantly interfere with emotional and physical quality of life. A provider should acquire a comprehensive medical and menstrual history and focused physical examination, as well as baseline laboratory studies, to determine the presence of anemia or underlying ble...
Source: Pediatric Annals - March 11, 2024 Category: Pediatrics Authors: Erin Isaacson Tazim Dowlut-McElroy Source Type: research