Exploring clinical variability in gelsolin amyloidosis: Brazilian family case study with confocal microscopy
We present three sisters with AGel amyloidosis, illustrating its clinical diversity. Patient 1, a 51-year-old, had bilateral ptosis, ocular discomfort, and dry eye syndrome due to cranial nerve involvement. Patient 2, a 53-year-old, experienced progressive bilateral visual impairment. Patient 3, a 50-year-old, exhibited right eye ectropion. Genetic analysis, with the identical mutation, heterozygous c.640G > A (p.Asp214Asn) mutation, confirmed AGel amyloidosis diagnoses, with common findings including lattice corneal amyloidosis, reduced corneal sensitivity, and recurrent corneal erosions. Neurological manifestations in...
Source: European Journal of Ophthalmology - April 15, 2024 Category: Opthalmology Authors: Caio Brenno Abreu B árbara Flores Culau Merlo Vin ícius da Silva Varandas Juliana de S á Freire Medrado Dias Source Type: research
Predictive model for iris melanoma
CONCLUSIONS: The predictive model provides direct diagnostic prediction of the lesion being iris melanoma expressed as probability (%). Use of a prediction calculator (app) can enhance decision-making and patient counselling. Further refinements can be undertaken with additional datasets, forming the basis for automated diagnosis.PMID:38609162 | DOI:10.1136/bjo-2023-324558 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 12, 2024 Category: Opthalmology Authors: Arun Singh Alexander Melendez-Moreno J ørgen Krohn Emily C Zabor Source Type: research
Predictive model for iris melanoma
CONCLUSIONS: The predictive model provides direct diagnostic prediction of the lesion being iris melanoma expressed as probability (%). Use of a prediction calculator (app) can enhance decision-making and patient counselling. Further refinements can be undertaken with additional datasets, forming the basis for automated diagnosis.PMID:38609162 | DOI:10.1136/bjo-2023-324558 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 12, 2024 Category: Opthalmology Authors: Arun Singh Alexander Melendez-Moreno J ørgen Krohn Emily C Zabor Source Type: research
Predictive model for iris melanoma
CONCLUSIONS: The predictive model provides direct diagnostic prediction of the lesion being iris melanoma expressed as probability (%). Use of a prediction calculator (app) can enhance decision-making and patient counselling. Further refinements can be undertaken with additional datasets, forming the basis for automated diagnosis.PMID:38609162 | DOI:10.1136/bjo-2023-324558 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 12, 2024 Category: Opthalmology Authors: Arun Singh Alexander Melendez-Moreno J ørgen Krohn Emily C Zabor Source Type: research
Recalcitrant postoperative bleeding after ectropion repair in the setting of undiagnosed chronic disseminated intravascular coagulation
Orbit. 2024 Apr 3:1-4. doi: 10.1080/01676830.2024.2331695. Online ahead of print.ABSTRACTDisseminated intravascular coagulation (DIC) is characterized by abnormal activation of the coagulation cascade, which leads to simultaneous hypercoagulation and excessive bleeding. While it typically occurs in systemic diseases, such as infection, inflammation, obstetric complications, and malignancy, it can rarely manifest postoperatively. This case report describes a patient who presented with prolonged, refractory bleeding after ectropion repair via a lateral tarsal strip procedure. Due to the inability to control the patient's ble...
Source: Cancer Control - April 3, 2024 Category: Cancer & Oncology Authors: Tatiana R Rosenblatt Lisa Y Lin Carolina A Chiou Nahyoung Grace Lee Gunsagar S Gulati Pavan K Bendapudi Natalie Wolkow Source Type: research
Recalcitrant postoperative bleeding after ectropion repair in the setting of undiagnosed chronic disseminated intravascular coagulation
Orbit. 2024 Apr 3:1-4. doi: 10.1080/01676830.2024.2331695. Online ahead of print.ABSTRACTDisseminated intravascular coagulation (DIC) is characterized by abnormal activation of the coagulation cascade, which leads to simultaneous hypercoagulation and excessive bleeding. While it typically occurs in systemic diseases, such as infection, inflammation, obstetric complications, and malignancy, it can rarely manifest postoperatively. This case report describes a patient who presented with prolonged, refractory bleeding after ectropion repair via a lateral tarsal strip procedure. Due to the inability to control the patient's ble...
Source: Orbit - April 3, 2024 Category: Opthalmology Authors: Tatiana R Rosenblatt Lisa Y Lin Carolina A Chiou Nahyoung Grace Lee Gunsagar S Gulati Pavan K Bendapudi Natalie Wolkow Source Type: research
Recalcitrant postoperative bleeding after ectropion repair in the setting of undiagnosed chronic disseminated intravascular coagulation
Orbit. 2024 Apr 3:1-4. doi: 10.1080/01676830.2024.2331695. Online ahead of print.ABSTRACTDisseminated intravascular coagulation (DIC) is characterized by abnormal activation of the coagulation cascade, which leads to simultaneous hypercoagulation and excessive bleeding. While it typically occurs in systemic diseases, such as infection, inflammation, obstetric complications, and malignancy, it can rarely manifest postoperatively. This case report describes a patient who presented with prolonged, refractory bleeding after ectropion repair via a lateral tarsal strip procedure. Due to the inability to control the patient's ble...
Source: Orbit - April 3, 2024 Category: Opthalmology Authors: Tatiana R Rosenblatt Lisa Y Lin Carolina A Chiou Nahyoung Grace Lee Gunsagar S Gulati Pavan K Bendapudi Natalie Wolkow Source Type: research
Recalcitrant postoperative bleeding after ectropion repair in the setting of undiagnosed chronic disseminated intravascular coagulation
Orbit. 2024 Apr 3:1-4. doi: 10.1080/01676830.2024.2331695. Online ahead of print.ABSTRACTDisseminated intravascular coagulation (DIC) is characterized by abnormal activation of the coagulation cascade, which leads to simultaneous hypercoagulation and excessive bleeding. While it typically occurs in systemic diseases, such as infection, inflammation, obstetric complications, and malignancy, it can rarely manifest postoperatively. This case report describes a patient who presented with prolonged, refractory bleeding after ectropion repair via a lateral tarsal strip procedure. Due to the inability to control the patient's ble...
Source: Orbit - April 3, 2024 Category: Opthalmology Authors: Tatiana R Rosenblatt Lisa Y Lin Carolina A Chiou Nahyoung Grace Lee Gunsagar S Gulati Pavan K Bendapudi Natalie Wolkow Source Type: research
Recalcitrant postoperative bleeding after ectropion repair in the setting of undiagnosed chronic disseminated intravascular coagulation
Orbit. 2024 Apr 3:1-4. doi: 10.1080/01676830.2024.2331695. Online ahead of print.ABSTRACTDisseminated intravascular coagulation (DIC) is characterized by abnormal activation of the coagulation cascade, which leads to simultaneous hypercoagulation and excessive bleeding. While it typically occurs in systemic diseases, such as infection, inflammation, obstetric complications, and malignancy, it can rarely manifest postoperatively. This case report describes a patient who presented with prolonged, refractory bleeding after ectropion repair via a lateral tarsal strip procedure. Due to the inability to control the patient's ble...
Source: Orbit - April 3, 2024 Category: Opthalmology Authors: Tatiana R Rosenblatt Lisa Y Lin Carolina A Chiou Nahyoung Grace Lee Gunsagar S Gulati Pavan K Bendapudi Natalie Wolkow Source Type: research
Recalcitrant postoperative bleeding after ectropion repair in the setting of undiagnosed chronic disseminated intravascular coagulation
Orbit. 2024 Apr 3:1-4. doi: 10.1080/01676830.2024.2331695. Online ahead of print.ABSTRACTDisseminated intravascular coagulation (DIC) is characterized by abnormal activation of the coagulation cascade, which leads to simultaneous hypercoagulation and excessive bleeding. While it typically occurs in systemic diseases, such as infection, inflammation, obstetric complications, and malignancy, it can rarely manifest postoperatively. This case report describes a patient who presented with prolonged, refractory bleeding after ectropion repair via a lateral tarsal strip procedure. Due to the inability to control the patient's ble...
Source: Orbit - April 3, 2024 Category: Opthalmology Authors: Tatiana R Rosenblatt Lisa Y Lin Carolina A Chiou Nahyoung Grace Lee Gunsagar S Gulati Pavan K Bendapudi Natalie Wolkow Source Type: research
Postoperative hyphema due to persistent tunica vasculosa lentis in glaucoma associated with neurofibromatosis —a case report
An 8-month-old girl referred from her pediatrician with a diagnosis of neurofibromatosis type 1 (NF1) presented with an enlarged cloudy cornea of the left eye and a swollen left side of the face. Her left eye had intraocular pressure (IOP) of 21 mm Hg, corneal diameter of 16 mm, ectropion uvea, cup:disk ratio of 0.9, axial length of 28.06 mm, and S-shaped upper lid deformity. Uneventful combined trabeculotomy-trabeculectomy with mitomycin C was performed. On postoperative day 1, there was a new total hyphema that persisted for 2 weeks. (Source: Journal of AAPOS)
Source: Journal of AAPOS - March 24, 2024 Category: Opthalmology Authors: Nader Bayoumi, Nihal El Shakankiry Tags: Short Report Source Type: research
The Cutler-Beard flap for upper eyelid reconstruction: Surgical indications revisited
CONCLUSIONS: Although non-bridging techniques are usually favored to reconstruct large upper eyelid defects, the Cutler-Beard bridge flap is a valuable technique in case of large horizontal defects where the vertical gap is greater than 15 mm. Further surgical steps are rarely necessary; however, alternative techniques should be considered following excision of highly malignant tumors.PMID:38384118 | DOI:10.1177/11206721241234417 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - February 22, 2024 Category: Opthalmology Authors: Elia Franzolin Flavia Quaranta Leoni Francesco M Quaranta Leoni Source Type: research
The Cutler-Beard flap for upper eyelid reconstruction: Surgical indications revisited
CONCLUSIONS: Although non-bridging techniques are usually favored to reconstruct large upper eyelid defects, the Cutler-Beard bridge flap is a valuable technique in case of large horizontal defects where the vertical gap is greater than 15 mm. Further surgical steps are rarely necessary; however, alternative techniques should be considered following excision of highly malignant tumors.PMID:38384118 | DOI:10.1177/11206721241234417 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - February 22, 2024 Category: Opthalmology Authors: Elia Franzolin Flavia Quaranta Leoni Francesco M Quaranta Leoni Source Type: research
Transcanthal Canthopexy for Involutional Lower Eyelid Entropion Corrects Horizontal Laxity
J Ophthalmol. 2024 Feb 13;2024:4694296. doi: 10.1155/2024/4694296. eCollection 2024.ABSTRACTIn this prospective observational study, we aimed to examine improvements in horizontal laxity after lower eyelid retractor advancement and transcanthal canthopexy for involutional lower eyelid entropion. The study included 19 sides in 15 patients with involutional entropion who underwent transcanthal canthopexy with the advancement of the lower eyelid retractor. Using the pinch test, the distance from the lowest part of the corneal limbus to the eyelid margin was measured using callipers. All measurements were performed preoperativ...
Source: Journal of Ophthalmology - February 21, 2024 Category: Opthalmology Authors: Shinjiro Kono Motohiro Kamei Source Type: research
