Shigella Bacteremia, Georgia, USA, 2002-2012 Shigella Bacteremia, Georgia, USA, 2002-2012
Bacteremia is an uncommon complication associated with Shigella infections. What are the risk factors for this rare infection?Emerging Infectious Diseases (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - January 20, 2020 Category: Infectious Diseases Tags: Infectious Diseases Journal Article Source Type: news

‘Normal’ Human Body Temperature Has Changed in the Last Century
Whether you have a stomachache, a wrist sprain or a chronic disease, one of the first things doctors and nurses will do at an appointment is take your temperature. A normal temperature means your body is humming along the way it should. A higher temperature means you have a fever, and shows your body could be fighting an infection. And since 1871, “normal” has meant 98.6°F (37°C). That number was determined by a German physician, based on millions of readings from 25,000 German patients, taken by sticking thermometers under their arms. When doctors in the U.S. and Europe repeated the experiment in local...
Source: TIME: Health - January 14, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized fever health inflammation Research Source Type: news

Drug-Resistant Dysentery Emerging Among Gay Men
THURSDAY, Dec. 19, 2019 -- Australian researchers are sounding the alarm over cases of a highly infectious intestinal illness that appear to be resistant to all forms of standard oral antibiotic treatment. The disease is called shigellosis, a form... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 19, 2019 Category: General Medicine Source Type: news

Drug-Resistant Dysentery Emerging Among Gay Men
Title: Drug-Resistant Dysentery Emerging Among Gay MenCategory: Health NewsCreated: 12/19/2019 12:00:00 AMLast Editorial Review: 12/19/2019 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - December 19, 2019 Category: Nutrition Source Type: news

Shigella strain resistant to all oral antibiotics circulating in Victoria
(University of Melbourne) Researchers have reported an extremely drug-resistant strain of Shigella circulating in Victoria with the vast majority of cases occurring in men who have sex with men. Shigella could previously be treated by oral antibiotics at home, the strain identified by Doherty Institute researchers is totally resistant to all oral antibiotics. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 18, 2019 Category: Infectious Diseases Source Type: news

UMSOM researchers to test vaccine designed to protect against serious illness from contaminated food
(University of Maryland School of Medicine) Each year, millions of people contract serious diarrheal illnesses typically from contaminated food and water. Among the biggest causes of diarrheal diseases are the bacteria Shigella and enterotoxigenic Escherichia coli (ETEC), and researchers at the University of Maryland School of Medicine are testing a vaccine designed to offer protection against these serious pathogens. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 10, 2019 Category: Infectious Diseases Source Type: news

Researchers uncover early adherence step in intestinal transit of Shigella
(Massachusetts General Hospital) The recent discovery of an early adherence step in the infection cycle could provide a new therapeutic target or even a new method for vaccine development. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 4, 2019 Category: Infectious Diseases Source Type: news

Eat The Seeds: Why The Germs In Apples May Be Good For You
(CNN) – Apples overflow with bacteria — about 100 million bacteria, many of which are healthy. Apple aficionados who swallow the core not only get extra fiber, flavonoids and flavor, they also ingest about 10 times more bacteria than people who discard the rough bits at the center, new research finds. And for those hoping to “keep the doctor away,” go organic, suggests the new study, which was published in Frontiers in Microbiology. Organic varieties carry a more diverse community of germs than the conventional and so could be healthier for us to eat. Apples are fruit celebrities, with more people e...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 26, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Apples CNN Source Type: news

Your Summer Beach Trip Could Put You at Risk of Getting Sick. Here ’s What You Need to Know
A sunburn may not be the only health consequence of your summer beach trips and pool days. A study published last year estimated that recreational water activities are related to 90 million illnesses each year in the U.S., with swimming as one of the primary catalysts of water-borne respiratory, ear and skin infections. Less frequently, according to federal data, pathogens found in pools, lakes, rivers and oceans can lead to more serious sickness, including gastrointestinal illnesses and—in very rare cases—exposure to flesh-eating bacteria. This month, for example, a Florida woman died from a flesh-eating bacte...
Source: TIME: Health - July 24, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Infectious Disease Source Type: news

A Fecal Parasite Is Causing More Disease Outbreaks, and Swimming Pools May Be to Blame, CDC Says
A recent announcement from the U.S. Centers for Disease Control and Prevention (CDC) may put a damper on summer fun. A fecal parasite often spread by swimming is causing an increasing number of illness outbreaks, the agency says. The number of disease outbreaks involving the parasite Cryptosporidium, also known as Crypto, increased by about 13% each year from 2009 to 2017, according to a new report from the CDC. People can become ill with cryptosporidiosis after exposure to contaminated human or animal fecal matter, developing symptoms including nausea, cramps and diarrhea that can last weeks and lead to serious malnutriti...
Source: TIME: Health - July 1, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized public health Source Type: news

Notes from the Field: Outbreak of Multidrug-Resistant Shigella sonnei Infections in a Retirement Community - Vermont, October-November 2018
In October 2018, the Vermont Department of Health notified CDC of an outbreak of diarrhea caused by Shigella sonnei in a retirement community in Chittenden County. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - May 2, 2019 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Outbreaks Shigellosis Source Type: news

Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes
In this study, we find that cleavage results in proteasome-mediated degradation of the amino-terminal domains of NLRP1B, liberating a carboxyl-terminal fragment that is a potent caspase-1 activator. Proteasome-mediated degradation of NLRP1B is both necessary and sufficient for NLRP1B activation. Consistent with our functional degradation model, we identify IpaH7.8, a Shigella flexneri ubiquitin ligase secreted effector, as an enzyme that induces NLRP1B degradation and activation. Our results provide a unified mechanism for NLRP1B activation by diverse pathogen-encoded enzymatic activities. (Source: ScienceNOW)
Source: ScienceNOW - April 3, 2019 Category: Science Authors: Sandstrom, A., Mitchell, P. S., Goers, L., Mu, E. W., Lesser, C. F., Vance, R. E. Tags: Immunology, Online Only r-articles Source Type: news

Southern Africa: Cyclone Survivors Risk 'Second Wave' of Loss With Disease Threat
[Thomson Reuters Foundation] Nairobi -At least half a million survivors of a powerful cyclone in southeast Africa are at risk of fatal diseases, from cholera and dysentery to malaria, aid workers warned on Thursday, as rescue teams struggled to reach flood-hit communities. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 22, 2019 Category: African Health Source Type: news

Sudan: Darfur - Measles, Dysentery, Pneumonia, and Eye Infections Spreading Fast in Jebel Marra
[Radio Dabanga] Jebel Marra -The Sudan Liberation Movement headed by Abdelwahid El Nur (SLM-AW) has renewed its appeal to local, regional, and international organisations to intervene to save the lives of people living in Jebel Marra against rapidly spreading measles, dysentery, pneumonia, and eye infections. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 14, 2019 Category: African Health Source Type: news

Shigellosis (Shigella Infection)
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - December 21, 2018 Category: General Medicine Source Type: news