Treating Nightmares in Posttraumatic Stress Disorder With Clonidine and Doxazosin
Condition:   Posttraumatic Stress Disorder Interventions:   Drug: Clonidine;   Drug: Doxazosin;   Drug: Placebo Sponsors:   Charite University, Berlin, Germany;   German Federal Ministry of Education and Research Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 4, 2022 Category: Research Source Type: clinical trials

Effects of autonomic nervous system activation on endothelial function in response to acute exercise in hypertensive individuals: study protocol for a randomized double-blind study
This study aims to examine the effects of ANS activation on FMD of the brachial artery in response to exercise in hypertensive individuals following a session of different types of exercise including aerobic exercise (AE), resistance exercise (RE), or combined exercise (CE).MethodsThirty-nine hypertensive volunteers aged 35 to 55  years will be randomly assigned to two exercise sessions: AE (40 min on a cycle ergometer at 60% of HR reserve), RE (4 lower limb sets with 12 repetitions at 60% 1-RM for 40 min), or CE (RE for 20 min + AE for 20 min). Each exercise group will be randomized to receive either an α1-adre...
Source: Trials - August 19, 2021 Category: Research Source Type: clinical trials

Alpha-1 Blockade for Alcohol Use Disorder (AUD)
Condition:   Alcohol Use Disorder (AUD) Interventions:   Drug: Doxazosin;   Drug: Placebo Sponsor:   Brown University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2019 Category: Research Source Type: clinical trials