What's new in midwifery - 2nd February 2022 (2/2/22)
Some things I noticed that you might want to know about too:Positive about Down SyndromeA website for parents expecting a baby with Down Syndrome, or new parents. The site is full of personal experiences and there are links to other organisations from the bottom of the home page.A Guardian storyreporting personal experiences of delays in scans.A cohort study conducted in Canada looking atmaternal and neonatal trauma following operative vaginal delivery, (Source: Browsing)
Source: Browsing - February 2, 2022 Category: Databases & Libraries Tags: midwifery Source Type: blogs
Oral History Study Explores What It ’s Like To Receive An Autism Diagnosis Later In Life
By guest blogger Dan Carney
A key development in autism research in the last twenty-odd years has been the use of less rigid methods such as interviews, fieldwork, and surveys, instead of those based on standardised measurements or other “laboratory-based” tasks. These looser approaches, in tandem with the increasing popularity of autobiographical writing by autistic people, have served to complement more traditional research by adding nuance and detail to understandings of the condition.
Now, a team from Australia led by Rozanna Lilley has used such an approach with a population underrepresented in autism resea...
Source: BPS RESEARCH DIGEST - December 16, 2021 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Autism guest blogger Qualitative The self Source Type: blogs
Fight Aging! Newsletter, November 15th 2021
This article will review the relationship between diabetes mellitus and AD as it relates to tau pathology. More understanding of the link between diabetes mellitus and AD could change the approach researchers and clinicians take toward both diseases, potentially leading to new treatments and preventative strategies in the future.
Signaling from White Fat Tissue Contributes to Age-Related Hair Follicle Dysfunction
https://www.fightaging.org/archives/2021/11/signaling-from-white-fat-tissue-contributes-to-age-related-hair-follicle-dysfunction/
Changes in fat tissue behavior in the skin take place with age,...
Source: Fight Aging! - November 14, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Vascular Dysfunction in the Brain as an Important Cause of Alzheimer's Disease
As we age, the vascular system becomes ever more dysfunctional in a number of ways. The density of capillaries declines, lowering the rate at which nutrients are delivered to energy-hungry tissues. The blood-brain barrier begins to leak, allowing inappropriate molecules and cells into the brain to provoke inflammation. Hypertension produces pressure damage to delicate tissues, and the ongoing rupture of tiny blood vessels, destroying small volumes of tissue. As researchers attempt to understand the relative importance of the many possible contributing causes of neurodegenerative conditions such as Alzheimer's disease, in t...
Source: Fight Aging! - November 10, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Five thoughts to think about when thinking about the speed of thought
This article was originally published on The Conversation.
News in Context:
Award-winning image shows neuroimaging progress in a century
Neuroplasticity as seen by one of its earliest scientist proponents: Neuroscience pioneer Santiago Ramón y Cajal
Can you grow your hippocampus? Yes. Here’s how, and why it matters
The post Five thoughts to think about when thinking about the speed of thought appeared first on SharpBrains. (Source: SharpBrains)
Source: SharpBrains - September 21, 2021 Category: Neuroscience Authors: The Conversation Tags: Brain/ Mental Health Education & Lifelong Learning cognitive electroencephalography functional magnetic resonance imaging movement myelination Neurons perception reaction-time speed of thought thinking thoughts Source Type: blogs
Autistic Children May Experience Less Variation In Their Bodily Emotional Responses
By guest blogger Dan Carney
Research into emotion processing in autistic people has mainly focused on how they understand others’ emotions. A more limited body of work into how autistic people process their own emotions has, however, suggested difficulties identifying and describing emotional experiences, and distinguishing between emotional states. The latter is potentially important, as it is associated with negative outcomes such as anxiety, depression, and self-injurious behavior, all of which have been suggested to occur more frequently in autism than in the general population.
So far, studie...
Source: BPS RESEARCH DIGEST - March 18, 2021 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Autism Emotion guest blogger The self Source Type: blogs
Down Syndrome children can greatly benefit from EARLY training
A child therapist who I very greatly respect, Ann Osterling (from Champaign, Illinois) wrote me an email message in response to my (undoubtedly superficial) comments about Down Sydrome that I thought everyone interested in helping these kids would enjoy reading. In her words:
You threw out the idea of intensive early intervention as one option for improving the learning outcomes of children with Down Syndrome. Not only do I agree, but we actually have already seen the tremendous positive impact of early intervention (in these) children.
If I had Down Syndrome when I was born 50 years ago, it is highly likely that I would h...
Source: On the Brain by Dr. Michael Merzenich, Ph.D. - March 1, 2021 Category: Neuroscience Authors: Dr. Merzenich Tags: Autism Origins, Treatments Brain Fitness BrainHQ Childhood Learning Cognitive Impairment in Children Cognitive impairments Language Development Reading and Dyslexia Source Type: blogs
Fight Aging! Newsletter, December 14th 2020
In conclusion, aging alters the cerebral vasculature to impair mitochondrial function and mitophagy and increase IL-6 levels. These alterations may impair BBB integrity and potentially reduce cerebrovascular health with aging.
Senescent Cells Fail to Maintain Proteostasis
https://www.fightaging.org/archives/2020/12/senescent-cells-fail-to-maintain-proteostasis/
Given the newfound consensus in the research community regarding the importance of senescent cells to degenerative aging, it isn't surprising to see a great deal more fundamental research into the biochemistry of cellular senescence now taking pl...
Source: Fight Aging! - December 13, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How Much of Cognitive Decline is Actively Maintained via Dysfunctional Cell States or Signaling, and is thus Quickly Reversible?
Demonstrations in which researchers adjust cell state or signaling to reverse cognitive decline in old mice suggest that a meaningfully large fraction of this age-related cognitive decline is actively maintained via dysfunctions in cell signaling and cell activity. Senescent cells and their inflammatory signaling are a likely culprit, though it is challenging to join the dots between signaling and specific mechanisms inside cells in the highly complex environment of cellular biochemistry. The important point is that much of the decline in cognitive function could be quickly reversed if specific signals and mechanisms can b...
Source: Fight Aging! - December 8, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Overlooking Down Syndrome
Dazee is frustrated because we have not included any discussion of Down Syndrome at this site, even while autism and other forms of severe disability are frequent topics of consideration. There are several reasons for our neglect.
First, the principal contributor to this blog has no experience with these kids. He hasn’t studied them (or animal models of this inherited malady) directly, in any meaningful way. There are better authorities out there in the scientific community.
Second, these children differ from other kids with cognitive impairments that we’ve studied, by the fact that their condition commonly r...
Source: On the Brain by Dr. Michael Merzenich, Ph.D. - November 1, 2020 Category: Neuroscience Authors: Dr. Merzenich Tags: Autism Origins, Treatments Brain Fitness BrainHQ Childhood Learning Cognitive Impairment in Children Cognitive impairments Language Development Source Type: blogs
Health Care 101 Continued: The allocation problem
We often hear sentiments to the effect that human life is infinitely precious, that you can ' t put a price on human life. While most people probably think this instinctively, it is conservatives, and particularly religious conservatives, who are most likely to try to apply the concept in reality. Do you remember the ravings about " death panels " when the Affordable Care Act passed? Of course there ' s nothing in the ACA that could conceivably be construed that way, but the scary meme was imported from arguments about single payer or, as in the UK, socialized medicine schemes.To put this in the simplest and starkest terms...
Source: Stayin' Alive - October 23, 2020 Category: American Health Source Type: blogs
What's new in midwifery - 15th October 2020
Language!First, a project designed to make us change the language we use when talking about people with Down ' s Syndrome,Language Creates Reality. It has produced some cards and other downloadable resources, and was featured on BBC Breakfast this morning (at 06.42). I think its principles apply to other areas too. So, not " a Down ' s baby " , but " a baby with Down ' s syndrome " . Not " suffering from " but " has " Down ' s Syndrome. And not " a normal baby " , but " a typical baby " . Note for University of Leicester members: I have made a clip in BoB which y...
Source: Browsing - October 15, 2020 Category: Databases & Libraries Tags: midwifery Source Type: blogs
Ostium primum ASD and clinical findings of ASD
Ostium primum ASD
Ostium primum atrial septal defect is part of the AV canal defects. In partial AV canal defect, ostium primum ASD is often associated with cleft anterior mitral leaflet producing mitral regurgitation. Tricuspid regurgitation may also be noted. In complete AV canal defect, there is associated canal VSD or inlet VSD and sometimes a single AV valve.
Ostium primum ASD being part of the endocardial cushion defects, may be associated with Down syndrome. They are more likely to develop pulmonary hypertension and Eisenmenger syndrome earlier. DiGeorge syndrome and Ellis-Van Creveld syndrome are the other conditi...
Source: Cardiophile MD - October 10, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: HBC Wide fixed split of second heart sound Source Type: blogs
Ventricular septal defect
Ventricular septal defects (VSD) can be divided into perimembranous, muscular, inlet and outlet VSDs, depending on the location. Of these perimembranous VSDs are the commonest. VSDs can decrease in size and undergo spontaneous closure. Spontaneous closure is most likely with small muscular and perimembranous VSD, while inlet and outlet VSDs are least likely to close.
Perimembranous ventricular septal defect
Perimembranous VSD with perimembranous aneurysm
Echocardiogram in ventricular septal defect: Parasternal long axis view shows the subaortic perimembranous ventricular septal aneurysm (marked by arrows). The color mosai...
Source: Cardiophile MD - October 10, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: HBC atrioventricular septal defect doubly committed VSD Eisenmenger complex Eisenmenger reaction Gerbode VSD Inlet ventricular septal defect maladie de Roger Muscular ventricular septal defect Outlet ventricular septal defect perimembr Source Type: blogs
General examination – eyes and facial dysmorphism
General examination – eyes and facial dysmorphism
Clinically examination is guided by the symptoms. Unless the history is not correlated with findings, important diagnostic possibilities may be missed. Clinical examination starts off with a focused general examination followed by a detailed examination of the cardiovascular system. Relevant points in other systems like basal crepitations, hepatosplenomegaly and neurological deficits should be looked for.
Examination strategy should be fitting to the clinical situation. When a patient presents to the emergency room, it should be a short but focused examination to perm...
Source: Cardiophile MD - September 21, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: HBC Source Type: blogs
