Remimazolam to prevent hemodynamic instability during catheter ablation under general anesthesia: a randomized controlled trial
CONCLUSIONS: Remimazolam was a viable option for general anesthesia for cardiac ablation. Remimazolam-based total intravenous anesthesia was associated with significantly fewer hypotensive events and vasopressor requirements than desflurane-based inhalational anesthesia was, without significantly more complications.STUDY REGISTRATION: ClinicalTrials.gov (NCT05486377); first submitted 1 August 2022.PMID:38609684 | DOI:10.1007/s12630-024-02735-z (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - April 12, 2024 Category: Anesthesiology Authors: Subin Yim Chang Ik Choi Insun Park Bon Wook Koo Ah Young Oh In-Ae Song Source Type: research

[Retracted] Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR ‑145‑5p/TOP2A axis
Mol Med Rep. 2024 Jun;29(6):94. doi: 10.3892/mmr.2024.13218. Epub 2024 Apr 12.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the tumour images shown in Fig. 6B on p. 8 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had either already been published or were under consideration for publication at around the same time. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to Mol...
Source: Molecular Medicine - April 12, 2024 Category: Molecular Biology Authors: Yi Du Xudong Zhang Hongwei Zhang Yiding Chen Shuying Zhu Jinjun Shu Hui Pan Source Type: research

How should visual function monitoring be performed and interpreted in surgery for suprasellar tumors?
CONCLUSIONS: OFR has a diagnostic element in the visual field, in which the maximal potential was recorded on the opposite side of the stimulus with monocular stimulation. Unambiguous determination required stimulation of different intensities in both eyes or 1 eye and multiple recording electrodes placed in the occiput. Monitoring the OFR provides real-time alerts, making it a valuable tool for visual function evaluation in suprasellar surgery.PMID:38608298 | DOI:10.3171/2024.1.JNS232118 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 12, 2024 Category: Neurosurgery Authors: Atsushi Sato Toshihiro Ogiwara Tetsuo Sasaki Kazuhiro Hongo Tetsuyoshi Horiuchi Source Type: research

[Retracted] Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR ‑145‑5p/TOP2A axis
Mol Med Rep. 2024 Jun;29(6):94. doi: 10.3892/mmr.2024.13218. Epub 2024 Apr 12.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the tumour images shown in Fig. 6B on p. 8 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had either already been published or were under consideration for publication at around the same time. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to Mol...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Yi Du Xudong Zhang Hongwei Zhang Yiding Chen Shuying Zhu Jinjun Shu Hui Pan Source Type: research

How should visual function monitoring be performed and interpreted in surgery for suprasellar tumors?
CONCLUSIONS: OFR has a diagnostic element in the visual field, in which the maximal potential was recorded on the opposite side of the stimulus with monocular stimulation. Unambiguous determination required stimulation of different intensities in both eyes or 1 eye and multiple recording electrodes placed in the occiput. Monitoring the OFR provides real-time alerts, making it a valuable tool for visual function evaluation in suprasellar surgery.PMID:38608298 | DOI:10.3171/2024.1.JNS232118 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 12, 2024 Category: Neurosurgery Authors: Atsushi Sato Toshihiro Ogiwara Tetsuo Sasaki Kazuhiro Hongo Tetsuyoshi Horiuchi Source Type: research

[Retracted] Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR ‑145‑5p/TOP2A axis
Mol Med Rep. 2024 Jun;29(6):94. doi: 10.3892/mmr.2024.13218. Epub 2024 Apr 12.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the tumour images shown in Fig. 6B on p. 8 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had either already been published or were under consideration for publication at around the same time. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to Mol...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Yi Du Xudong Zhang Hongwei Zhang Yiding Chen Shuying Zhu Jinjun Shu Hui Pan Source Type: research

Remimazolam to prevent hemodynamic instability during catheter ablation under general anesthesia: a randomized controlled trial
CONCLUSIONS: Remimazolam was a viable option for general anesthesia for cardiac ablation. Remimazolam-based total intravenous anesthesia was associated with significantly fewer hypotensive events and vasopressor requirements than desflurane-based inhalational anesthesia was, without significantly more complications.STUDY REGISTRATION: ClinicalTrials.gov (NCT05486377); first submitted 1 August 2022.PMID:38609684 | DOI:10.1007/s12630-024-02735-z (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - April 12, 2024 Category: Anesthesiology Authors: Subin Yim Chang Ik Choi Insun Park Bon Wook Koo Ah Young Oh In-Ae Song Source Type: research

Development of a predictive model for hypoxia due to sedatives in gastrointestinal endoscopy: a prospective clinical study in Korea
CONCLUSIONS: High BMI, neck circumference, and Mallampati score were independently associated with hypoxia during sedative endoscopy. We constructed a model with acceptable performance for predicting hypoxia during sedative endoscopy.PMID:38605689 | DOI:10.5946/ce.2023.198 (Source: Clinical Endoscopy)
Source: Clinical Endoscopy - April 12, 2024 Category: Gastroenterology Authors: Jung Wan Choe Jong Jin Hyun Seong-Jin Son Seung-Hak Lee Source Type: research

How should visual function monitoring be performed and interpreted in surgery for suprasellar tumors?
CONCLUSIONS: OFR has a diagnostic element in the visual field, in which the maximal potential was recorded on the opposite side of the stimulus with monocular stimulation. Unambiguous determination required stimulation of different intensities in both eyes or 1 eye and multiple recording electrodes placed in the occiput. Monitoring the OFR provides real-time alerts, making it a valuable tool for visual function evaluation in suprasellar surgery.PMID:38608298 | DOI:10.3171/2024.1.JNS232118 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 12, 2024 Category: Neurosurgery Authors: Atsushi Sato Toshihiro Ogiwara Tetsuo Sasaki Kazuhiro Hongo Tetsuyoshi Horiuchi Source Type: research

[Retracted] Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR ‑145‑5p/TOP2A axis
Mol Med Rep. 2024 Jun;29(6):94. doi: 10.3892/mmr.2024.13218. Epub 2024 Apr 12.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the tumour images shown in Fig. 6B on p. 8 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had either already been published or were under consideration for publication at around the same time. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to Mol...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Yi Du Xudong Zhang Hongwei Zhang Yiding Chen Shuying Zhu Jinjun Shu Hui Pan Source Type: research

Development of a predictive model for hypoxia due to sedatives in gastrointestinal endoscopy: a prospective clinical study in Korea
CONCLUSIONS: High BMI, neck circumference, and Mallampati score were independently associated with hypoxia during sedative endoscopy. We constructed a model with acceptable performance for predicting hypoxia during sedative endoscopy.PMID:38605689 | DOI:10.5946/ce.2023.198 (Source: Clinical Endoscopy)
Source: Clinical Endoscopy - April 12, 2024 Category: Gastroenterology Authors: Jung Wan Choe Jong Jin Hyun Seong-Jin Son Seung-Hak Lee Source Type: research

[Retracted] Propofol modulates the proliferation, invasion and migration of bladder cancer cells through the miR ‑145‑5p/TOP2A axis
Mol Med Rep. 2024 Jun;29(6):94. doi: 10.3892/mmr.2024.13218. Epub 2024 Apr 12.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the tumour images shown in Fig. 6B on p. 8 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had either already been published or were under consideration for publication at around the same time. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to Mol...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Yi Du Xudong Zhang Hongwei Zhang Yiding Chen Shuying Zhu Jinjun Shu Hui Pan Source Type: research

The predictive role of carotid artery flow time for anesthesia-induced hypotension in high-risk elderly patients
AbstractHypotension induced by general anesthesia is associated with postoperative complications, increased mortality, and morbidity, particularly elderly patients. The aim of this study was to investigate the effectiveness of corrected carotid artery flow time (FTc) for predicting hypotension following anesthesia induction in patients over 65 years old.  After faculty ethical committee approval and written informed consent, 138 patients (65 years and older, ASA physical status I–III) who scheduled for elective surgery were included in this study. In the pre-operative anesthesia unit, the carotid artery FTc value was me...
Source: Journal of Clinical Monitoring and Computing - April 12, 2024 Category: Information Technology Source Type: research

Remimazolam to prevent hemodynamic instability during catheter ablation under general anesthesia: a randomized controlled trial
ConclusionsRemimazolam was a viable option for general anesthesia for cardiac ablation. Remimazolam-based total intravenous anesthesia was associated with significantly fewer hypotensive events and vasopressor requirements than desflurane-based inhalational anesthesia was, without significantly more complications.Study registrationClinicalTrials.gov (NCT05486377); first submitted 1 August 2022. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - April 12, 2024 Category: Anesthesiology Source Type: research

NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research