Effects of propofol, desflurane, and spinal anesthesia on intraocular pressure during lumbar disc herniation surgery: a randomized controlled study
CONCLUSIONS: Our findings suggest that volatile anesthesia (desflurane) and spinal anesthesia are linked to lower IOP in the prone position among patients undergoing spinal surgery, in comparison to those receiving total intravenous anesthesia. There is a need to test the results with more comprehensive, population-based studies in different patient groups. ClinicalTrials gov ID: NCT06070480.PMID:38436174 | DOI:10.26355/eurrev_202402_35462 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: E T Yilmaz B O Kele ş Source Type: research

Efficacy and safety of general anesthesia with caudal block for inguinal hernioplasty in children: a randomized controlled trial
CONCLUSIONS: In children, the combination of general anesthesia with caudal block, compared to general anesthesia only, is more efficient in suppressing visceral pain, leading to better hemodynamic stability, and reducing the consumption of medicines in the perioperative period.PMID:38436173 | DOI:10.26355/eurrev_202402_35461 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: M Pandurov I Fabri Galambos R Zdravkovic A Uram Benka G Rakic N Boskovic S Vickovic M Tatic M Lukic Sarkanovic T Tubic M Preveden N Dra čina N Videnovic D Krtinic A Jakovljevic N Djokovic A Jakovljevic B Draskovic Source Type: research

Effects of propofol, desflurane, and spinal anesthesia on intraocular pressure during lumbar disc herniation surgery: a randomized controlled study
CONCLUSIONS: Our findings suggest that volatile anesthesia (desflurane) and spinal anesthesia are linked to lower IOP in the prone position among patients undergoing spinal surgery, in comparison to those receiving total intravenous anesthesia. There is a need to test the results with more comprehensive, population-based studies in different patient groups. ClinicalTrials gov ID: NCT06070480.PMID:38436174 | DOI:10.26355/eurrev_202402_35462 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: E T Yilmaz B O Kele ş Source Type: research

Efficacy and safety of general anesthesia with caudal block for inguinal hernioplasty in children: a randomized controlled trial
CONCLUSIONS: In children, the combination of general anesthesia with caudal block, compared to general anesthesia only, is more efficient in suppressing visceral pain, leading to better hemodynamic stability, and reducing the consumption of medicines in the perioperative period.PMID:38436173 | DOI:10.26355/eurrev_202402_35461 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: M Pandurov I Fabri Galambos R Zdravkovic A Uram Benka G Rakic N Boskovic S Vickovic M Tatic M Lukic Sarkanovic T Tubic M Preveden N Dra čina N Videnovic D Krtinic A Jakovljevic N Djokovic A Jakovljevic B Draskovic Source Type: research

Comparison of prophylaxis strategy for postoperative nausea and vomiting and its incidence before and after the implementation of 5-hydroxytryptamine 3 in surgical setting: a single-center, retrospective study
ConclusionThe availability of ondansetron increased the number of patients with adequate PONV prophylaxis, but did not decrease the incidence of PONV. (Source: Journal of Anesthesia)
Source: Journal of Anesthesia - March 4, 2024 Category: Anesthesiology Source Type: research

Propofol-induced hippocampal Neurotoxicity: A mitochondrial perspective
This study seeks to provide a comprehensive literature review of the effects of propofol toxicity on the hippocampus via mitochondria and to suggest translational suggestions based on these molecular results.PMID:38428475 | DOI:10.1016/j.brainres.2024.148841 (Source: Brain Research)
Source: Brain Research - March 1, 2024 Category: Neurology Authors: Moein Ebrahimi Ali Dabbagh Firoozeh Madadi Source Type: research

Efficacy of propofol-supplemented cardioplegia on biomarkers of organ injury in patients having cardiac surgery using cardiopulmonary bypass: a statistical analysis plan for the ProMPT-2 randomised controlled trial
The ProMPT-2 trial (Propofol for Myocardial Protection Trial #2) aims to compare the safety and efficacy of low- and high-dose propofol supplementation of the cardioplegia solution during adult cardiac surgery ve... (Source: Trials)
Source: Trials - February 29, 2024 Category: General Medicine Authors: Helena Smartt, Gianni D. Angelini, Ben Gibbison and Chris A. Rogers Tags: Update Source Type: research

Evaluation of Quality of Recovery With Quality of Recovery-15 Score After Closed-Loop Anesthesia Delivery System-Guided Propofol Versus Desflurane General Anesthesia in Patients Undergoing Transabdominal Robotic Surgery: A Randomized Controlled Study
CONCLUSIONS: Automated propofol TIVA administered by CLADS is superior to desflurane inhalation GA with respect to early postoperative recovery as comprehensively assessed on the QoR-15 scoring system. The effect of combined automated precision anesthesia and surgery (robotics) techniques on postoperative recovery may be explored further.PMID:38416594 | DOI:10.1213/ANE.0000000000006849 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 28, 2024 Category: Anesthesiology Authors: Nitin Sethi Amitabh Dutta Goverdhan D Puri Jayashree Sood Prabhat K Choudhary Manish Gupta Bhuwan C Panday Savitar Malhotra Source Type: research

Evaluation of Quality of Recovery With Quality of Recovery-15 Score After Closed-Loop Anesthesia Delivery System-Guided Propofol Versus Desflurane General Anesthesia in Patients Undergoing Transabdominal Robotic Surgery: A Randomized Controlled Study
CONCLUSIONS: Automated propofol TIVA administered by CLADS is superior to desflurane inhalation GA with respect to early postoperative recovery as comprehensively assessed on the QoR-15 scoring system. The effect of combined automated precision anesthesia and surgery (robotics) techniques on postoperative recovery may be explored further.PMID:38416594 | DOI:10.1213/ANE.0000000000006849 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 28, 2024 Category: Anesthesiology Authors: Nitin Sethi Amitabh Dutta Goverdhan D Puri Jayashree Sood Prabhat K Choudhary Manish Gupta Bhuwan C Panday Savitar Malhotra Source Type: research

Sevoflurane preconditioning in living liver donation is associated with better initial graft function after pediatric transplantation: a retrospective study
ConclusionSignificantly fewer children who received a graft from a donor in whom only sevoflurane was used to maintain anesthesia developed IPGF. Although additional research is needed, this preconditioning strategy may provide an option to prevent IPGF after living liver donation. (Source: Perioperative Medicine)
Source: Perioperative Medicine - February 28, 2024 Category: Surgery Source Type: research

Permutation Entropy Does Not Track the Electroencephalogram-Related Manifestations of Paradoxical Excitation During Propofol-Induced Loss of Responsiveness: Results From a Prospective Observational Cohort Study
CONCLUSIONS: PeEn and beta ratio seem suitable parameters to monitor the state transition during anesthesia induction. The decreasing PeEn values suggest a reduction of signal complexity and information content, which may very well describe the clinical situation at LOR. The beta ratio mainly focuses on the loss of power in the gamma-band. PeEn, in particular, may present a single parameter capable of tracking the LOR transition without being affected by paradoxical excitation.PMID:38412114 | DOI:10.1213/ANE.0000000000006919 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 27, 2024 Category: Anesthesiology Authors: Julian Ostertag Robert Zanner Gerhard Schneider Matthias Kreuzer Source Type: research

Effect of Remimazolam Supplementation on Propofol Requirements During Hysteroscopy: A Double-Blind, Dose-Response Study
CONCLUSIONS: For women undergoing hysteroscopic procedures, remimazolam at doses from 0.1 to 0.2 mg·kg-1 reduced the EC50 of propofol inhibiting response to cervical dilation and the total propofol requirement. Whether the combination could improve perioperative outcomes deserves further investigation.PMID:38412109 | DOI:10.1213/ANE.0000000000006921 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 27, 2024 Category: Anesthesiology Authors: Yan-Hong Zhou Shu-Xi Li Lin Li Chun-Mei Deng Jian-Jun Shen Dong-Xin Wang Xin-Zhong Chen Li-Li Xu Source Type: research

Permutation Entropy Does Not Track the Electroencephalogram-Related Manifestations of Paradoxical Excitation During Propofol-Induced Loss of Responsiveness: Results From a Prospective Observational Cohort Study
CONCLUSIONS: PeEn and beta ratio seem suitable parameters to monitor the state transition during anesthesia induction. The decreasing PeEn values suggest a reduction of signal complexity and information content, which may very well describe the clinical situation at LOR. The beta ratio mainly focuses on the loss of power in the gamma-band. PeEn, in particular, may present a single parameter capable of tracking the LOR transition without being affected by paradoxical excitation.PMID:38412114 | DOI:10.1213/ANE.0000000000006919 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 27, 2024 Category: Anesthesiology Authors: Julian Ostertag Robert Zanner Gerhard Schneider Matthias Kreuzer Source Type: research

Effect of Remimazolam Supplementation on Propofol Requirements During Hysteroscopy: A Double-Blind, Dose-Response Study
CONCLUSIONS: For women undergoing hysteroscopic procedures, remimazolam at doses from 0.1 to 0.2 mg·kg-1 reduced the EC50 of propofol inhibiting response to cervical dilation and the total propofol requirement. Whether the combination could improve perioperative outcomes deserves further investigation.PMID:38412109 | DOI:10.1213/ANE.0000000000006921 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - February 27, 2024 Category: Anesthesiology Authors: Yan-Hong Zhou Shu-Xi Li Lin Li Chun-Mei Deng Jian-Jun Shen Dong-Xin Wang Xin-Zhong Chen Li-Li Xu Source Type: research