Propofol (Propofol Injectable Emulsion) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 13, 2016 Category: Drugs & Pharmacology Source Type: news

AstraZeneca enters commercialisation agreement with Aspen for anaesthetic medicines portfolio
AstraZeneca today announced it has entered into a commercialisation agreement with Aspen Global Incorporated (AGI), part of the Aspen Group, for rights to its global anaesthetics portfolio outside the US. The agreement covers seven established medicines - Diprivan (general anaesthesia), EMLA (topical anaesthetic) and five local anaesthetics (Xylocaine/Xylocard/Xyloproct, Marcaine, Naropin, Carbocaine and Citanest). (Source: World Pharma News)
Source: World Pharma News - June 9, 2016 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

Reduced brain connectivity in frontal cortex linked to propofol-induced loss of consciousness
(Mary Ann Liebert, Inc./Genetic Engineering News) A new study shows that loss of responsiveness induced by propofol, a commonly used anesthetic, is associated with greatly diminished brain connectivity in the frontal cortex and significant changes in resting state brain networks. The study, based on a novel method for constructing total brain connectivity maps and comparing them with results obtained for resting state networks, is published in Brain Connectivity. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 14, 2016 Category: Global & Universal Source Type: news

Cocaine-associated cardiotoxicity: a systematic review yields no answers
Christopher Siesarchik/shutterstock.com 3 out of 5 stars Treatment of cocaine cardiovascular toxicity: a systematic review. Richards JR et al. Clin Toxicol 2016 Feb 26 [Epub ahead of print] Abstract This paper is the most frustrating thing I’ve read since I force marched my way through the “Oxen of the Sun” chapter of James Joyce’s Ulysses. I must say that, despite its difficulties, the Joyce selection — with its obstetric setting and drunken medical students — was much more fun. There is considerable controversy among toxicologists, emergency physicians, and cardiologists as to the best agent...
Source: The Poison Review - April 6, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical cardiotoxicity cocaine systematic review Source Type: news

Patient experience of sexual hallucinations after propofol-induced painless abortion may lead to violence against medical personnel - Yang Z, Yi B.
Painless abortion is an outpatient surgical procedure performed under general anesthesia, which requires an appropriate anesthetic reagent that must be safe, comfortable for the patient, and highly controllable. At present, fentanyl and propofol are first-... (Source: SafetyLit)
Source: SafetyLit - April 2, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Severe bupropion overdose and ECMO: two great saves
ChaNaWiT/shutterstock.com 3.5 out of 5 stars Two Cases of Refractory Cardiogenic Shock Secondary to Bupropion Successfully Treated with Veno-Arterial Extracorporeal Membrance Oxygenation. Heise CW et al. J Med Toxicol 2016 Feb 8 [Epub Ahead of Print] Abstract This awesome, exciting paper from Banner University Medical Center in Phoenix describes two teenagers with severe bupropion overdose who survived refractory cardiac arrest after veno-arterial extracorporeal membrane oxygenation (VA-ECMO): Case 1: A 15-year-old girl was brought to hospital after ingesting up to 90 150-mg bupropion tablets. She had a seizure en route...
Source: The Poison Review - February 12, 2016 Category: Toxicology Authors: Leon Tags: Medical burpropion ECMO extracorporeal membrane oxygenation Source Type: news

Sevoflurane Versus Propofol During Cardiac SurgerySevoflurane Versus Propofol During Cardiac Surgery
Does sevoflurane or propofol exhibit more favorable cardioprotective effects during cardiac surgery? BMC Anesthesiology (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - January 20, 2016 Category: Pathology Tags: Anesthesiology Journal Article Source Type: news

Letters to the Editor: Propranolol and Propofol
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - January 1, 2016 Category: Emergency Medicine Tags: Letters to the Editor Source Type: news

Propofol as a controlled substance: poison or remedy - Jeon YT.
[Abstract unavailable] Language: en... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - December 11, 2015 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

InFocus: No Proven Efficacy for Ketofol over Propofol Alone
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - October 31, 2015 Category: Emergency Medicine Tags: InFocus Source Type: news

Required Propofol Dose for Anesthesia and Time to Emerge Are Affected by the Use of AntiepilepticsRequired Propofol Dose for Anesthesia and Time to Emerge Are Affected by the Use of Antiepileptics
How do neurological disorders and their medications affect propofol dosing? BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 15, 2015 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Computer-Assisted Propofol Hailed by GastroenterologistsComputer-Assisted Propofol Hailed by Gastroenterologists
The sedation system, used instead of an anesthesiologist to deliver propofol during routine endoscopy, led to shorter recovery times and overall physician satisfaction, according to a clinical report. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 21, 2015 Category: Consumer Health News Tags: Anesthesiology News Source Type: news

Computer-Assisted Sedation a Hit With Endoscopists (CME/CE)
(MedPage Today) -- Faster and more predictable recovery seen with propofol. (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - May 20, 2015 Category: Gastroenterology Source Type: news

Computer-assisted sedation reduces patient recovery time by almost 20 percent
(Digestive Disease Week) Use of computer-assisted propofol sedation for routine upper endoscopy and colonoscopy reduced recovery room time by almost 20 percent, according to a study released today at Digestive Disease Week® 2015. The study, conducted by researchers at Virginia Mason Medical Center, Seattle, Wash., showed the process yielded a better recovery experience than the commonly used combination of midazolam and fentanyl. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 19, 2015 Category: Cancer & Oncology Source Type: news

Dexmedetomidine Versus Remifentanil After Spinal SurgeryDexmedetomidine Versus Remifentanil After Spinal Surgery
Does remifentanil or dexmedetomidine offer better postoperative pain control when used as an adjuvant in propofol-based anesthesia during spinal surgery? BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 5, 2015 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news