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Neuropilin-1 Binding Peptide as Fusion to Diphtheria Toxin Induces Apoptosis in Non-small Cell Lung Cancer Cell Line
CONCLUSION: Taken together, DTA-triCRGDK is a promising tool for targeted therapy of NRP-1 overexpressing cancer cells.PMID:38584554 | DOI:10.2174/0113816128292382240325074032 (Source: Current Pharmaceutical Design)
Source: Current Pharmaceutical Design - April 8, 2024 Category: Drugs & Pharmacology Authors: Sara Eghtedari Mahdi Behdani Fatemeh Kazemi-Lomedasht Source Type: research

Immunogenicity and safety of adsorbed diphtheria-purified pertussis-tetanus-inactivated polio (Sabin strain)-Haemophilus type b conjugate combined vaccine (DPT-IPV-Hib) in healthy Japanese Infants ≥ 2 and & lt; 43 months of Age: A phase III, multicenter, active controlled, assessor-blinded, randomized, parallel-group study
CONCLUSION: A single-agent Gobik, the first DPT-IPV-Hib pentavalent vaccine approved in Japan, was confirmed to simultaneously provide primary and booster immunizations against Hib infection, pertussis, diphtheria, tetanus, and poliomyelitis and to have a preventive effect and safety comparable to concomitant vaccination with Hib (ActHIB®) and DPT-IPV quadrivalent vaccine (Tetrabik).PMID:38582691 | DOI:10.1016/j.vaccine.2023.03.077 (Source: Vaccine)
Source: Vaccine - April 6, 2024 Category: Allergy & Immunology Authors: Takashi Nakano Masumi Hasegawa Mai Endo Keiko Matsuda Hoshio Tamai Source Type: research

Global vaccine coverage and childhood survival estimates: 1990-2019
CONCLUSION: Vaccines continue to reduce childhood mortality significantly, especially in Gavi-supported countries, emphasizing the need for increased investment in routine immunization programmes.PMID:38562199 | PMC:PMC10976869 | DOI:10.2471/BLT.23.290129 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Haijun Zhang Bryan Patenaude Haonan Zhang Mark Jit Hai Fang Source Type: research

Anti-NMDA Receptor Encephalitis, Human Papillomavirus, and microRNA
CONCLUSION: This finding suggests that in cases where individuals receiving HPV vaccination experience psychiatric or neurological symptoms, it should be considered to diagnose anti-NMDA receptor encephalitis, given the exclusion of other possible complications.PMID:38549528 | DOI:10.2174/0109298673264615231124072130 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - March 29, 2024 Category: Chemistry Authors: Hsiuying Wang Source Type: research