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Genetically engineered immunotoxin shows early promise in patients with B-cell malignancies
DT2219, a new bispecific ligand-directed diphtheria toxin, was found to be safe and clinically effective in a small group of patients with relapsed/refractory B-cell malignancies, according to phase I clinical trial data. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 13, 2015 Category: Science Source Type: news

Genetically engineered immunotoxin shows early promise in patients with B-cell malignancies
(American Association for Cancer Research) DT2219, a new bispecific ligand-directed diphtheria toxin, was found to be safe and clinically effective in a small group of patients with relapsed/refractory B-cell malignancies, according to phase I clinical trial data. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 13, 2015 Category: Cancer & Oncology Source Type: news

A Simple Tetanus Vaccine Could Help Treat The Most Common And Deadly Brain Tumor
NEW YORK (AP) — Can a tetanus shot help treat brain cancer? A small study hints that it might. A dose of tetanus vaccine let patients live longer when added to an experimental treatment for the most common and deadly kind of brain tumor, researchers report. It "put the immune system on high alert," paving the way for the experimental treatment to work better in attacking the disease, said researcher Kristen Batich of the Duke University Medical Center. In a paper released Wednesday by the journal Nature, she and others describe a study of 12 patients. Some who got the tetanus shot lived years longer than...
Source: Science - The Huffington Post - March 12, 2015 Category: Science Source Type: news

Woman with brain cancer has survived for 9 years thanks to vaccine
Sandy Hillburn, 68, from New Jersey, was offered a slot in an experimental study at Duke University involving adding the tetanus-diphtheria vaccine to a new treatment for glioblastoma. (Source: the Mail online | Health)
Source: the Mail online | Health - March 12, 2015 Category: Consumer Health News Source Type: news

Anti-Vaccination Activists To Blame For Bosnia's Measles Outbreak, Say Experts
SARAJEVO, Bosnia-Herzegovina (AP) — Medical experts warned Friday the anti-vaccination lobby is growing in Bosnia, using scientifically discredited arguments to stoke parental fears in the worst-affected country in Europe's measles outbreak. This trend — combined with a generation that could not be immunized because of lack of vaccines during Bosnia's 1992-95 war — has led to 5,340 measles cases in Bosnia, according to the World Health Organization. "I am increasingly hearing from parents about their fears due to the stuff they read on the Internet," Dr. Gordana Banduka, a pediatrician from Pal...
Source: Healthy Living - The Huffington Post - March 1, 2015 Category: Consumer Health News Source Type: news

New vaccine is an important advance in stopping cervical and other HPV-related cancers
If you knew that a vaccine could prevent your daughter or son from developing a relatively common and potentially deadly cancer later in life, would you have her or him get it? Such a vaccine is available, and it’s about to get even better than it is now — but fewer than half of all teens have gotten it. I am talking about a vaccine against the human papilloma virus (HPV). It is responsible for cervical cancer, which strikes 12,000 women each year in the United States and kills 4,000. Only 15% of women diagnosed with advanced cervical cancer survive for five years or more — a grim statistic. HPV also caus...
Source: New Harvard Health Information - February 19, 2015 Category: Consumer Health News Authors: Gregory Curfman, M.D. Tags: Vaccines cervical cancer cervical cancer vaccine HPV hpv vaccine human papilloma virus Source Type: news

Got Science? Vaccinating Ourselves Against Misinformation
It is dismaying that fears and misinformation about vaccines have led the scourge of measles to return in the United States some 15 years after it had been officially eradicated here. And it's especially discouraging to see some early 2016 presidential hopefuls such as Chris Christie and Rand Paul pander on the issue rather than taking a strong evidence-based stance because the facts could not be more clear: Vaccines are safe and they save lives. One of the tragic aspects of this story is that some of the 102 measles cases so far this year in the United States have struck children under a year old who are too young to rec...
Source: Science - The Huffington Post - February 12, 2015 Category: Science Source Type: news

UC plans to require vaccinations for incoming students starting in 2017
The University of California will require incoming students to be screened for tuberculosis and vaccinated for measles, mumps, rubella, chicken pox, meningococcus, tetanus and whooping cough under a plan set to take effect in 2017. Currently, the UC system only requires students to be vaccinated against hepatitis B, though several campuses have additional requirements. The plan — designed to help protect the health of students and campus communities — has been in the works for a year. But the need is more pressing than ever, given the current multistate measles outbreak and the re-emergence of other vaccine-pre...
Source: UCLA Newsroom: Health Sciences - February 7, 2015 Category: Universities & Medical Training Source Type: news

Here’s how many are opting out of measles, other vaccinations in Missouri
As measle outbreaks continue to pop up around the country, records show the number of immunization exemptions in Missouri have risen for three consecutive years — and not just for measles. Records from the Missouri Department of Health and Senior Services show a steady increase in requests for exemptions for four major vaccines: diphtheria, polio, measles and hepatitis B. The majority of the requests were made on religious grounds as opposed to medical reasons. Measles tops the list of most-requested… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - February 6, 2015 Category: Pharmaceuticals Authors: Corey Noles Source Type: news

Here’s how many are opting out of measles, other vaccinations in Missouri
As measle outbreaks continue to pop up around the country, records show the number of immunization exemptions in Missouri have risen for three consecutive years — and not just for measles. Records from the Missouri Department of Health and Senior Services show a steady increase in requests for exemptions for four major vaccines: diphtheria, polio, measles and hepatitis B. The majority of the requests were made on religious grounds as opposed to medical reasons. Measles tops the list of most-requested… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - February 6, 2015 Category: Biotechnology Authors: Corey Noles Source Type: news

Ghana: Ghana Failed to Immunize 220kK Children in 2014
[Ghanaian Chronicle]Two hundred and twenty thousand children were not immunized last year against the six killer diseases - polio, diphtheria, tuberculosis, pertussis (whooping cough), measles and tetanus, according to Dr. Joan Awanyo-Akaba, the Civil Society rep on the board of the Global Alliance for Vaccines and Immunization (GAVI). (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 29, 2015 Category: African Health Source Type: news

Pertussis Immunity Lasts Only Few Years After DTaP ImmunizationPertussis Immunity Lasts Only Few Years After DTaP Immunization
The average duration of protection against pertussis after diphtheria-tetanus-acellular pertussis (DTaP) immunization is only about three years, according to a review and meta-analysis of a dozen studies. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 6, 2015 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate) Vaccine
(Source: What's New at CBER)
Source: What's New at CBER - December 31, 2014 Category: Biomedical Science Source Type: news

Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine
(Source: What's New at CBER)
Source: What's New at CBER - December 31, 2014 Category: Biomedical Science Source Type: news

Diphtheria and Tetanus Toxoids Adsorbed, STN 103944
(Source: What's New at CBER)
Source: What's New at CBER - December 31, 2014 Category: Biomedical Science Source Type: news

Diphtheria & Tetanus Toxoids Adsorbed, STN 103919
(Source: What's New at CBER)
Source: What's New at CBER - December 31, 2014 Category: Biomedical Science Source Type: news

Mission launched to cover kids against preventable diseases
The diseases are diphtheria, whooping cough, tetanus, polio, tuberculosis, measles and hepatitis B, an official statement here said. (Source: The Economic Times)
Source: The Economic Times - December 25, 2014 Category: Consumer Health News Source Type: news

What The NHL Mumps Outbreak Teaches Us About Immunity
The unprecedented outbreak of mumps -- a contagious and occasionally dangerous virus -- in a professional sports league, the NHL, has led to player quarantines, cancelled events and, most recently, movement among NBA clubs that often share facilities to distance themselves from arenas and practice facilities also used by hockey players. The NFL, though its players don't have contact with hockey teams, has taken note as well, according to an ESPN report -- they know it could happen in their league, too. Although the first mumps alert in the NHL -- from the Anaheim Ducks -- happened in mid-September, and the first official ...
Source: Science - The Huffington Post - December 24, 2014 Category: Science Source Type: news

Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed
(Source: What's New at CBER)
Source: What's New at CBER - December 2, 2014 Category: Biomedical Science Source Type: news

I-Team: Vaccine Rates Plummeting In Parts Of Mass.
BOSTON (CBS) – Childhood vaccines are credited with virtually wiping out a host of awful diseases, yet many parents are still concerned about the shots. Two and a half year old Collin let out a scream as he got his latest vaccine in the office of his Cape Cod pediatrician, but Dr. Sharon Daley believes that discomfort is a small price to pay for the protection the shot offers. Dr. Daley, who is also the chief of pediatrics at Cape Cod Hospital, explained, “Whooping cough, and diphtheria, measles, bacterial meningitis, even influenza; these diseases used to cause thousands of deaths each year.” Dr. Daley...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 13, 2014 Category: Consumer Health News Authors: deanreddington Tags: Health i-Team Local News Seen On WBZ-TV Syndicated Local Watch Listen Cape Cod Cape Cod Hospital Dr. Sharon Daley immunization Kim Shea Lauren Leamanczyk Vaccine Source Type: news

Tdap Vaccine Generally Safe in Pregnancy (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Administration of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine in … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 12, 2014 Category: Primary Care Source Type: news

7 Steps To Ensure Ebola Doesn't Disrupt Your International Travel
Is it safe to travel? Should we cancel our long-planned family safari in Botswana? Can I get Ebola from an airplane seat? For the last two decades, I've been helping people find the best doctors, treatments and medical information -- and I've never seen the kind of health panic among clients like I do now. (Yes, No and Extraordinarily unlikely are the short answers to these questions, by the way). For expert advice, I checked in with Dr. Michael Callahan, an associate physician in the Division of Infectious Diseases at Massachusetts General Hospital/Harvard Medical School. Callahan ran one of the Department of Defense pr...
Source: Science - The Huffington Post - October 27, 2014 Category: Science Source Type: news

Which state does the best job of vaccinating kids? Mississippi
When it comes to vaccinating children against diseases such as measles, diphtheria and whooping cough, Mississippi is the model for the nation, new federal data show. (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - October 16, 2014 Category: Science Source Type: news

Adacel (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 6, 2014 Category: Drugs & Pharmacology Source Type: news

Tenivac (Tetanus and Diphtheria Toxoids Adsorbed) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 3, 2014 Category: Drugs & Pharmacology Source Type: news

Vaccination with Tetanus, Diphtheria, and Acellular Pertussis Vaccine of Pregnant Women Enrolled in Medicaid — Michigan, 2011–2013
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - September 26, 2014 Category: American Health Source Type: news

Office Champions Report: Focused Effort Can Improve Immunization Rates
The AAFP recently published its Child and Adolescent Immunization Office Champions Project report, highlighting outcomes from the 20 participating practices. The post-project data for teen immunizations, in particular, revealed increases over baseline for all immunization rates measured, from a 12.35 percent uptick for tetanus, diphtheria and acellular pertussis vaccination to a 100 percent rise for HPV vaccination. (Source: AAFP News)
Source: AAFP News - September 23, 2014 Category: Primary Care Source Type: news

Report: Focused Effort Can Improve Vaccine Rates
The AAFP recently published its Child and Adolescent Immunization Office Champions Project report, highlighting outcomes from the 20 participating practices. The post-project data for teen immunizations, in particular, revealed increases over baseline for all immunization rates measured, from a 12.35 percent uptick for tetanus, diphtheria and acellular pertussis vaccination to a 100 percent rise for HPV vaccination. (Source: AAFP News)
Source: AAFP News - September 23, 2014 Category: Primary Care Source Type: news

Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein] Suspension for Intramuscular Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 19, 2014 Category: Drugs & Pharmacology Source Type: news

Menactra (Polysaccharide Diphtheria Toxoid Conjugate Vaccine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 12, 2014 Category: Drugs & Pharmacology Source Type: news

‘Infant Cocooning’ Becoming More Popular Among New Parents
BOSTON (CBS) – Angela Keizer and Brian Miller are counting the days until the birth of their baby girl. “This Baby is very unexpected and very special,” Angela said. They didn’t think they would be able to have a baby and so they are taking no chances when she arrives. “We are going to request that family members vaccinate before they see her,” Brian said. They want to make sure everyone is up-to-date with their pertussis, diphtheria and influenza vaccines before they meet the baby. It’s called infant cocooning and it is supported by the American Academy of Pediatrics. According t...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 26, 2014 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen American Academy Of Pediatrics diphtheria Dr. Mallika Marshall infant cocooning influenza vaccines pertussis Source Type: news

August is National Immunization Awareness Month
! This year, the National Public Health Information Coalition (NPHIC) has designated a specific population focus for each week: August 3-9 — A Healthy Start: Babies and Pregnant Women August 10-16 — Back to School: Children, Preteens & Teens August 17-23 — Off to the Future: Young Adults August 24-30 — Not Just for Kids: Adults Immunizations are important for individuals of all ages. Often times there are concerns as to whether or not we should continue immunizing our children (and ourselves), however, the Centers for Disease Control (CDC) maintains vaccinations are worthwhile: It’s true, ...
Source: Network News - August 11, 2014 Category: Databases & Libraries Authors: Naomi Gonzales Tags: Consumer Health General (all entries) Public Health Source Type: news

A Diphtheria Toxin Negative Selection in RNA Interference Screening
RNA interference (RNAi) screening is a powerful technique for understanding the molecular biology of cancer and searching drug targets. Genes and their upstream activators that are essential for the survival of cancer cells often dictate cancer formation/progression. Hence, they are preferable therapeutic targets. Identifying these genes using RNAi is, however, problematic because knocking them down leads to cell death. Here we describe a diphtheria toxin (DT) negative selection method to circumvent the problem of cell death in RNAi screening. DT fails to kill mouse cells due to the lack of functional DT receptor (DTR). Th...
Source: Springer protocols feed by Cancer Research - July 17, 2014 Category: Cancer & Oncology Source Type: news

MMR jab unlikely to harm young babies
A young couple's baby was given the MMR jab by mistake "potentially putting her life at risk", The Daily Telegraph website reports misleadingly. Giving a baby the wrong vaccine is a serious mistake; fortunately, the error was quickly noticed and the baby appears not to have been seriously harmed. Unfortunately, the Telegraph has taken a sensationalist approach by quoting the most extreme possible reaction – anaphylaxis – without stating that this is extremely rare and treatable. The Telegraph's coverage says, “Newborns under six months must not be given the vaccine ...
Source: NHS News Feed - June 20, 2014 Category: Consumer Health News Tags: QA articles Pregnancy/child Source Type: news

Well: Protecting Newborns Against Whooping Cough
Research suggests that pregnant women who get a vaccination to protect against tetanus, diphtheria and whooping cough are helping their babies, too. (Source: NYT Health)
Source: NYT Health - May 26, 2014 Category: Consumer Health News Authors: By NICHOLAS BAKALAR Tags: Family Whooping Cough Babies and Infants medicine and health Featured Vaccination and Immunization Source Type: news

Well: Protecting Newborns Against Whooping Cough
Research suggests that pregnant women who get a vaccination to protect against tetanus, diphtheria and whooping cough are helping their babies, too. (Source: NYT)
Source: NYT - May 26, 2014 Category: Nutrition Authors: By NICHOLAS BAKALAR Tags: Family Whooping Cough Babies and Infants medicine and health Featured Vaccination and Immunization Source Type: news

Vaccines not linked with autism, study finds
Conclusion This systematic review and meta-analysis has found no association between vaccination and the development of autism or autism spectrum disorder. The cohort studies included in the systematic review had information on more than a million children from four different countries.  This was a valuable and rigorous piece of research that will hopefully reassure parents who have any concerns about getting their children vaccinated against childhood diseases. As with all studies, this research has limitations. It excluded data from the Vaccine Adverse Event Reporting System (VAERS) in the United Sta...
Source: NHS News Feed - May 20, 2014 Category: Consumer Health News Tags: Medication Neurology Pregnancy/child Mental health Source Type: news

NO link between autism and childhood vaccines, new survey has found
No statistical data to support a link between vaccines for measles, mumps, rubella, diphtheria, tetanus and whooping cough and the development of autism or autism spectrum disorders, according to research by University of Sydney. (Source: the Mail online | Health)
Source: the Mail online | Health - May 19, 2014 Category: Consumer Health News Source Type: news

Namibia: Vaccination for Every Infant and Child
[Namibia Economist]The immunization coverage for 2013 shows some improvement over previous years, with 89% of infants receiving the recommended three doses of Pentavalent vaccine which protects against five diseases (diphtheria, whooping cough, tetanus, hepatitis and haemophilus influenza); and 83% vaccinated against measles. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 16, 2014 Category: African Health Source Type: news

Receiving Tdap vaccine during pregnancy appears safe, study shows
A preliminary study finds that receipt of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine in the third trimester of pregnancy did not increase the risk of adverse events for the mother or infant. In addition, the authors found high concentrations of pertussis antibodies in infants during the first two months of life, a period during which infants are at the highest risk of pertussis-associated illness or death. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 4, 2014 Category: Science Source Type: news

Menveo (Meningococcal (Groups A, C, Y and W-135) Oligosaccharide Diphtheria CRM197) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 25, 2014 Category: Drugs & Pharmacology Source Type: news

Sticking to Vaccination Schedules Cuts Infection Risk (FREE)
By Amy Orciari Herman Following the recommended vaccination schedules for diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae type b (DTaP-IPV-Hib) and measles, mumps, and rubella (MMR) is associated with a reduction in hospitalizations … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - February 26, 2014 Category: Primary Care Source Type: news

There are new vaccine requirements for the 2014-2015 school year. Schedule your school and sports physicals now to avoid the rush!.
Welcome to Pediatric Health Associates!Did you know that you do not have to wait until the hectic summer is here to get your child's yearly physical?   School and sports physicals are valid for 1 year from the date they are completed.   This means at any point your child can be seen for their kindergarten, sixth grade and ninth grade checkup and get their school forms completed. Checkups are not only a time to approve school and sports exams--- they are far more-- following up on past development and growth issues, as well as re-assessing any ongoing medical issues that your child may have.  Further, if...
Source: Pediatric Health Associates - February 21, 2014 Category: Pediatrics Tags: Healthy Habits Vaccination Information Source Type: news

Doctors Resist Deadly Vaccine
An infant in intensive care at the Holy Family Hospital in New Delhi. Indian hospitals prefer traditional DPT vaccines. Credit: Holy Family Hospital.By Ranjit DevrajNEW DELHI, Feb 8 2014 (IPS) A spate of sudden infant deaths following vaccination in India has prompted leading paediatricians to call for stronger regulatory mechanisms to evaluate new vaccines for safety and efficacy before their acceptance into the national immunisation programme. According to data obtained from the Union Ministry of Health and Family Welfare, over the last one year 54 babies are recorded to have died soon after receiving the newly introduce...
Source: IPS Inter Press Service - Health - February 8, 2014 Category: Global & Universal Authors: Ranjit Devraj Tags: Active Citizens Aid Asia-Pacific Civil Society Development & Aid Editors' Choice Featured Headlines Health Human Rights Population Regional Categories TerraViva Europe TerraViva United Nations Children India Vaccines Source Type: news

What Causes Muscle Weakness?
Discussion Muscle tone is the slight tension that is felt in a muscle when it is voluntarily relaxed. It can be assessed by asking the patient to relax and then taking the muscles through a range of motion such as moving the wrists, forearm and upper arm. Muscle strength is the muscle’s force against active resistance. Impaired strength is called weakness or paresis. There are 5 levels of muscle strength. 0 = No muscle contraction detected 1 = Barely detected flicker of contraction 2 = Active movement with gravity eliminated 3 = Active movement against gravity 4 = Active movement against gravity and some resistance ...
Source: PediatricEducation.org - December 9, 2013 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Diphtheria
Title: DiphtheriaCategory: Diseases and ConditionsCreated: 6/27/2008 12:00:00 AMLast Editorial Review: 11/26/2013 12:00:00 AM (Source: MedicineNet Hepatitis C General)
Source: MedicineNet Hepatitis C General - November 26, 2013 Category: Infectious Diseases Source Type: news

Vaccination 'a civic duty' according to new report
This report provides useful information about adult immunisations in the UK as well as useful recommendations for increasing immunisation coverage, particularly among social care workers. However, it does not replace current guidelines for recommended vaccines. Currently recommended vaccines for adults in the UK are described below.    Who produced the report? This report, titled ‘Immune response. Adult immunisation in the UK’ was written by the UK’s International Longevity Centre (ILC-UK). According its website, the ILC-UK is a registered charity and independent think tank dedicated to address...
Source: NHS News Feed - November 19, 2013 Category: Consumer Health News Tags: Medical practice Medication Older people QA articles Source Type: news

Tdap Vaccination in Teens May Cut Infant Hospitalizations Tdap Vaccination in Teens May Cut Infant Hospitalizations
Widespread vaccination of adolescents against tetanus-diphtheria-acellular pertussis, instituted in 2006, has been associated with the decreased hospitalization of infants. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 22, 2013 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Vaccinating Teens Against Pertussis Seems to Reduce Hospitalizations in Infants (FREE)
By Joe Elia The CDC's 2006 recommendation to implement tetanus-diphtheria-acellular pertussis (Tdap) vaccination universally in adolescents apparently lowered pertussis admissions among infants, a Pediatrics study finds. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 22, 2013 Category: Primary Care Source Type: news