The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Mol Biol Cell - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis
Curr Issues Mol Biol. 2022 Aug 5;44(8):3481-3495. doi: 10.3390/cimb44080240.ABSTRACTOsteoarthritis (OA), the most common joint disease, shows an increasing prevalence in the aging population in industrialized countries. OA is characterized by low-grade chronic inflammation, which causes degeneration of all joint tissues, such as articular cartilage, subchondral bone, and synovial membrane, leading to pain and loss of functionality. Erythrocytes, the most abundant blood cells, have as their primary function oxygen transport, which induces reactive oxygen species (ROS) production. For this reason, the erythrocytes have sever...
Source: Current Issues in Molecular Biology - August 25, 2022 Category: Molecular Biology Authors: Alessia Mariano Irene Bigioni Francesco Misiti Luigi Fattorini Anna Scotto d'Abusco Angelo Rodio Source Type: research
Molecules, Vol. 27, Pages 3637: The Fight against Infection and Pain: Devil & rsquo;s Claw (Harpagophytum procumbens) a Rich Source of Anti-Inflammatory Activity: 2011 & ndash;2022
Molecules, Vol. 27, Pages 3637: The Fight against Infection and Pain: Devil’s Claw (Harpagophytum procumbens) a Rich Source of Anti-Inflammatory Activity: 2011–2022
Molecules doi: 10.3390/molecules27113637
Authors:
Nomagugu Gxaba
Madira Coutlyne Manganyi
Harpagophytum procumbens subsp. procumbens (Burch.) DC. ex Meisn. (Sesame seed Family—Pedaliaceae) is a popular medicinal plant known as Devil’s claw. It is predominantly distributed widely over southern Africa. Its impressive reputation is embedded in its traditional uses as an indigenous herbal plant for the treat...
Source: Molecules - June 6, 2022 Category: Chemistry Authors: Nomagugu Gxaba Madira Coutlyne Manganyi Tags: Review Source Type: research
Antioxidant and DNA damage protective activities of selected endophytic actinobacteria isolated from Harpagophytum procumbens: A Kalahari desert-adapted plant
Given that synthetic antioxidants are currently in use and have been demonstrated to have known negative side effects, it is important to look for natural antioxidant sources. Endophytic actinobacteria, especially those associated with medicinal plants, are one understudied source. The goal of this study was to investigate whether the secondary metabolites of endophytic actinobacteria isolat... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - February 22, 2022 Category: Complementary Medicine Source Type: research
Molecules, Vol. 26, Pages 7014: Leucosceptoside A from Devil & rsquo;s Claw Modulates Psoriasis-like Inflammation via Suppression of the PI3K/AKT Signaling Pathway in Keratinocytes
Molecules, Vol. 26, Pages 7014: Leucosceptoside A from Devil’s Claw Modulates Psoriasis-like Inflammation via Suppression of the PI3K/AKT Signaling Pathway in Keratinocytes
Molecules doi: 10.3390/molecules26227014
Authors:
Ivanka K. Koycheva
Liliya V. Mihaylova
Monika N. Todorova
Zhivka P. Balcheva-Sivenova
Kalina Alipieva
Claudio Ferrante
Giustino Orlando
Milen I. Georgiev
Psoriasis is a chronic inflammatory skin condition characterized by abnormal keratinocyte proliferation and differentiation that is accompanied with dysregulated immune response and abnormal vascularization. Devil&...
Source: Molecules - November 20, 2021 Category: Chemistry Authors: Ivanka K. Koycheva Liliya V. Mihaylova Monika N. Todorova Zhivka P. Balcheva-Sivenova Kalina Alipieva Claudio Ferrante Giustino Orlando Milen I. Georgiev Tags: Article Source Type: research