Assessment of the Improvement in Cognitive Levels of Postmenopausal Depression Patients by Estrogen
Conditions: Postmenopausal Depression; Estrogen Interventions: Drug: Fematon (estradiol/estradiol-norethindrone acetate combination tablet package)+SSRIs; Drug: SSRIs Sponsors: Xiao Wang Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
Accelerated Intermittent Theta Burst Stimulation (iTBS) Deep Transcranial Magnetic Stimulation (Deep TMS) Multicenter Clinical Study
Conditions: Major Depressive Disorder Interventions: Device: Brainsway Deep TMS System Sponsors: Brainsway Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
TEEM-GIFTS: A Gamified mHealth to Reduce Post-Discharge Suicide Risk
Conditions: Suicide Interventions: Other: TEEM Sponsors: Shenzhen Kangning Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
Income Volatility and Mental Health, Pilot Study
Conditions: Depression Interventions: Behavioral: Work opportunities Sponsors: Cornell University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
Developing a Peer Support Intervention for Depression in SCD
Conditions: Subjective Cognitive Decline; Depression in Old Age Interventions: Behavioral: PeersCOG Sponsors: Massachusetts General Hospital; National Institutes of Health (NIH) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
New Investigational Stimulation Protocol for Treatment of Major Depression Disorder (MDD)
Conditions: Major Depressive Disorder Interventions: Device: Brainsway Deep TMS System Sponsors: Brainsway Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
NRx Pharmaceuticals Announces Data-Lock of Phase 2b/3 Trial of NRX-101 in Suicidal Treatment Resistant Bipolar Depression
RADNOR, Pa., April 8, 2024. NRx Pharmaceuticals, Inc. ( " NRx Pharmaceuticals " , the " Company " ), a clinical-stage biopharmaceutical company, today announced that the Company has achieved data-lock in its Phase 2b/3 Suicidal Treatment Resistant Bipolar... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - April 9, 2024 Category: Pharmaceuticals Source Type: clinical trials
Overcontrol and Suicide in PTSD
Conditions: Compulsive Personality Disorder; Stress Disorders, Post-Traumatic Interventions: Other: Functional MRI Sponsors: VA Office of Research and Development Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
Psilocybin in Chronic Low Back Pain and Depression
Conditions: Chronic Low-back Pain; Depression Interventions: Drug: Psilocybin; Drug: Methylphenidate Sponsors: Johns Hopkins University; National Center for Complementary and Integrative Health (NCCIH) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
Exercise in Pregnancy and Risk of Postpartum Depression
Conditions: Depression; Pregnancy Related Interventions: Behavioral: exercise in pregnancy Sponsors: Federico II University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
CA-LINC Black Youth Suicide Detection and Intervention Study
Conditions: Suicide; Suicide Prevention Interventions: Behavioral: CA-LINC Intervention; Behavioral: Treatment as Usual Sponsors: University of North Carolina, Charlotte; National Institute of Mental Health (NIMH) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders
Conditions: Mood Disorders; Suicidal Ideation; Depressive Episode Interventions: Drug: Subanesthetic dose intravenous esketamine; Device: Modified electroconvulsive therapy Sponsors: Capital Medical University; Wuhu Fourth People ' s Hospital; The Second People ' s Hospital of Dali Bai Autonomous Prefecture; Inner Mongolia Autonomous Region Mental Health Center; Beijing Chaoyang District Third Hospital; Beijing Daxing District Xinkang Hospital; Capital ' s Funds for Health Improvement and Research Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 9, 2024 Category: Research Source Type: clinical trials
Validation of the predictive value of BDNF -87 methylation for antidepressant treatment success in severely depressed patients —a randomized rater-blinded trial
AbstractBackgroundBrain-derived neurotrophic factor (BDNF) is essential for antidepressant treatment of major depressive disorder (MDD). Our repeated studies suggest that DNA methylation of a specific CpG site in the promoter region of exon IV of the BDNF gene (CpG -87) might be predictive of the efficacy of monoaminergic antidepressants such as selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and others. This trial aims to evaluate whether knowing the biomarker is non-inferior to treatment-as-usual (TAU) regarding remission rates while exhibiting significantly fewer ad...
Source: Trials - April 9, 2024 Category: Research Source Type: clinical trials
A Single-case Design to Investigate a Compensatory Brain Game Supporting Goal Management Training Intervention in a Psychiatric Brain Injury Population
Conditions: Acquired Brain Injury; Depressive Symptoms; Anxiety; Executive Dysfunction Interventions: Behavioral: Compensatory brain game supporting Goal Management Training intervention Sponsors: ProPersona Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2024 Category: Research Source Type: clinical trials
The PredictPlusPrevent Study
Conditions: Depression; Anxiety Disorders Interventions: Behavioral: Predictplusprevent intervention; Other: Psychoeducational intervention Sponsors: The Mediterranean Institute for the Advance of Biotechnology and Health Research Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2024 Category: Research Source Type: clinical trials
