Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression
Conditions: Unipolar Depression; Bipolar Disorder Interventions: Device: iTBS; Device: cTBS; Device: Sham Sponsors: Jakub Antczak; Institute of Psychiatry and Neurology, Warsaw Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials

Low-Income Group Psilocybin Assisted Therapy for Depression
Conditions: Depression Interventions: Drug: Psilocybin Sponsors: Matthew Hicks Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials

Evaluation of blood biomarker-based diagnostic aid in outpatients suffering from depression
Conditions: Depressive Disorder; Bipolar Disorder; Bipolar Depression Interventions: Other: there is no intervention Sponsors: Les Toises - Psychiatry and Psychotherapy Center Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials

Theta-Burst Stimulation for Bipolar Depression
Conditions: Bipolar Depression; Bipolar Disorder; Treatment- Resistant Bipolar Disorder; Type 2 Bipolar Disorder Interventions: Device: iTBS Stimulation; Device: Sham iTBS Stimulation Sponsors: Centre for Addiction and Mental Health; University Health Network, Toronto Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials

Theta-burst rTMS in schizophrenia to ameliorate negative and cognitive symptoms: study protocol for a double-blind, sham-controlled, randomized clinical trial
DiscussionThis is a double-blind, sham-controlled, randomized medical device study to assess the efficacy and safety of an augmented theta-burst rTMS treatment in schizophrenia. We hypothesize that social cognition and negative symptoms of patients on active therapy will improve significantly compared to patients on sham treatment.Trial registrationThe study protocol is registered at “ClinicalTrials.gov” with the following ID: NCT05100888. All items from the World Health Organization Trial Registration Data Set are registered. Initial release: 10/19/2021. (Source: Trials)
Source: Trials - April 17, 2024 Category: Research Source Type: clinical trials

Arrivo Bio Initiates Large Phase 2b Clinical Trial in Major Depressive Disorder with Novel SIRT6 Activator SP-624
MORRISVILLE, N.C.--(BUSINESS WIRE) April 16, 2024 -- Arrivo BioVentures announced today a significant step forward in the fight against major depressive disorder (MDD) with the dosing of the first patient in the SP-624-202 clinical trial. This... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - April 16, 2024 Category: Pharmaceuticals Source Type: clinical trials

Effectiveness of Brahma Kumaris Raja Yoga Meditation on Quality of Life of Youth in the Deaddiction Center of Biratnagar
Conditions: Prevalence; Depression; Happiness; Quality of Life; Anxiety Interventions: Behavioral: Rajyoga Meditation Practice Sponsors: Manipur International University; Brahmakumaris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

Schema therapy versus treatment as usual for outpatients with difficult-to-treat depression: study protocol for a parallel group randomized clinical trial (DEPRE-ST)
DiscussionThis trial will provide evidence on the beneficial and harmful effects, as well as the cost-effectiveness of schema therapy versus treatment as usual for outpatients with difficult-to-treat depression. The results can potentially improve treatment for a large and understudied patient group.Trial registrationClinicalTrials.gov NCT05833087. Registered on 15th April 2023 (approved without prompts for revision on 27th April 2023). (Source: Trials)
Source: Trials - April 16, 2024 Category: Research Source Type: clinical trials

Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention
Conditions: Postpartum Depression; Postpartum Anxiety; Stress Interventions: Behavioral: M.Bapp; Behavioral: App-based parenting education Sponsors: Women and Infants Hospital of Rhode Island Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials

TrueBlue Clinical Study - Investigating the Use of a Mobile Phone App TrueBlue for Monitoring Depression and Anxiety
Conditions: Depression; Depression, Postpartum; Anxiety in Pregnancy; Anxiety; Anhedonia; Perinatal Depression Interventions: Device: TrueBlue App Sponsors: BlueSkeye AI; Institute of Mental Health Nottingham; Nottinghamshire Healthcare NHS Trust; Nottingham University Hospitals NHS Trust Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials

Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation
Conditions: Suicidal Ideation; Suicidal Ideas Interventions: Drug: Ketamine Hydrochloride; Drug: Normal saline Sponsors: Children ' s Hospital of Eastern Ontario Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials

#Chatsafe Netherlands: a Social Media Intervention to Improve Dutch Young People's Safe Communication About Suicide Online
Conditions: Suicide Prevention; Communication; Social Media Interventions: Behavioral: Social Media campaign Sponsors: 113 Suicide Prevention; Orygen; Mind Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials

ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder
Conditions: Bipolar Disorder Interventions: Behavioral: Acceptance and Commitment Therapy; Other: Bipolar Disorder Psychoeducation Therapy Sponsors: Beny Lafer Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials

Distant Reiki Therapy on Postpartum Period Fatigue and Depression
Conditions: PostPartum Depression Interventions: Behavioral: Reiki energy therapy Sponsors: Aksaray University Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials

LoVE4MUM: Virtual Engagement for Preventing Postpartum Depression - Pilot RCT Protocol
Conditions: Postpartum Depression; Maternal Behavior; mHealth Intervention; Mental Health Issue Interventions: Device: LoVE4MUM mobile application Sponsors: National Institutes of Health, Ministry of Health Malaysia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 15, 2024 Category: Research Source Type: clinical trials