Single-cell transcriptome characterization of oral mucosal fibroblasts
CONCLUSIONS: To evaluate the role of fibroblasts in tissue homeostasis and wound healing accomplished by integrating and analyzing fibroblasts from normal skin and oral mucosal tissue from various sites, this study identifies the differences in fibroblast subpopulation composition and function between these two tissue types in healthy conditions, and provides an understanding of oral mucosa and skin homeostasis and cellular function at the transcriptomic level. The findings of this study may serve as a basis for future research in this area.PMID:38583017 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Jiong Zhao Guo Bai Chi Yang Source Type: research

Inhibition of connexin 43-mediated hemichannel activity promotes odontoblast differentiation of human dental pulp cells induced by lipopolysaccharide
CONCLUSIONS: Cx43 participates in the regulation of dental pulp repair after injury, and its expression shows a downward trend as a whole. Inhibition of Cx43 or blocking of HC promotes LPS-induced ERK signal activity and odontoblast differentiation of hDPCs.PMID:38583020 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: An-Ni Zhang Can-Can Ding Li-Ping Huang Shi-Ting Li Source Type: research

Improvements in appropriate placement of dental sealants after implementation of a clinical decision support system
CONCLUSIONS: Integration of a CDSS into the EHR as part of a quality improvement program was effective in increasing the delivery of sealants in eligible first and second molars of children aged 5 through 15 years and considered at high risk of developing caries.PRACTICAL IMPLICATIONS: An EHR-based CDSS can be implemented to improve standardization and provide timely and appropriate patient care in dental practices.PMID:38583172 | DOI:10.1016/j.adaj.2024.02.009 (Source: Journal of the American Dental Association)
Source: Journal of the American Dental Association - April 7, 2024 Category: Dentistry Authors: Joanna Mullins Ryan Brandon Nicholas Skourtes Elsbeth Kalenderian Muhammad Walji Source Type: research

A survey of parents of preschool children on their perception of bad oral habits
CONCLUSIONS: Parents' awareness of bad oral habits is not high, and parents' educational background is a risk factor for parents' awareness of bad oral habits. It is necessary to improve parents' awareness of oral habits, strengthen health education of bad oral habits, especially for parents with special signs, and improve the attention to oral health care, to achieve early detection, early prevention, early treatment and timely treatment, so as to prevent the occurrence and development of malocclusion.PMID:38583034 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Ying Kang Qin Ding Sun Wang Source Type: research

Clinical observation of minimally invasive extraction of lower third molar by retaining the buccal bone plate
CONCLUSIONS: The patients who preserve the buccal bone plate by minimally invasive extraction of impacted mandibular teeth have less reaction and better wound healing.PMID:38583033 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Zhen Xu Guo-Dong Jia Wang Yi Source Type: research

Evaluation of the 5-year clinical restoration effect of implants retained complete overdentures with Locator attachments in 48 patients
CONCLUSIONS: Implants retained complete overdentures with Locator attachments are effective in long term clinical observation. Complications are mainly found in peri-implant mucosal bleeding on probing and vertical alveolar bone absorption, and tended to increase gradually over time. The fracture of the implant retains complete overdenture bases and the fall off or fracture of the artificial teeth are the second serious complications. Overdenture base with metal frame at the location of the Locator abutment and the midline of the anterior area should be strengthened, and narrow diameter implants should be avoided as far as...
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Tuan-Feng Zhou Xue Yang Hua Zhang Zhi-Yong Zhang Quan Chen Source Type: research

The relationship between the expression of PGE2 and COX-2 and the osteogenic activity and oxygen level of alveolar bone
CONCLUSIONS: The expression of PGE2 and COX-2 is highly negatively correlated with ALP and oxygen levels. Clinical treatment may consider increasing oxygen levels, increasing oxygen partial pressure, and regulating ALP levels by drugs, so as to change the inflammatory condition of periodontitis or other dental diseases.PMID:38583031 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Juan-Juan Su Hong-Ting Chen Xu Wang Qiang Jin Lin Wang Source Type: research

A novel periodontal endoscopy-aided non-incisional periodontal regeneration technique :a case series study
CONCLUSIONS: For angular resorption site of alveolar bone, NIT treatment can obtain good periodontal regeneration results without flap inversion.PMID:38583030 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Jia-Hong Shi Jing-Wen Li Li-Shan Jiang Lang Lei Hou-Xuan Li Source Type: research

Effects of orthodontic treatment combined with bone level implant in repairing dentition defect
CONCLUSIONS: Orthodontic treatment combined with bone level implants can improve the success rate of implantation and masticatory efficiency, enhance the periodontal health of implants, and increase the patients' satisfaction with implants.PMID:38583029 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Ru-Juan Gong Lei He Source Type: research

Evaluation of the effect of MTF-S on the removal of impacted mandibular wisdom teeth with complete or partial crown impaction
CONCLUSIONS: Compared with partially impacted wisdom teeth, the extraction of completely impacted wisdom teeth has a longer surgical time. For completely impacted wisdom teeth, MTF-S is beneficial for reducing postoperative pain, swelling and mouth opening limitations. For partially impacted wisdom teeth, MTF-S is beneficial for reducing postoperative swelling and mouth opening limitations, but the effect is not significant in reducing patient pain.PMID:38583028 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Cheng Kang Ting Zhu Shan-Feng Luo Yi-Yi Lou Source Type: research

Review of clinical effects of disk-up sinus reamer(DSR)-based internal sinus floor elevation with implantation in 10 years
CONCLUSIONS: The DSR-based internal sinus floor elevation with implantation is a reliable and stable bone augmentation operation for vertical bone defect in maxillary posterior region, with a 10-year cumulative retention rate of no less than 94%. Initial bone height, elevated bone height, mucosal perforation, implant length, implant torsion, diabetes, smoking and periodontitis are the important factors affecting the long-term retention rate of implants.PMID:38583027 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Kai-Yue Zhang Ze-Yu Han Shuai Jiang Hao Xu Fan Li Bao-Dong Zhao Source Type: research

A qualitative study on the needs of patients with mandibular defects for occlusal function
CONCLUSIONS: To establish a unified and standardized program of occlusal function exercise, doctors and nurses should pay attention to various obstacles of patients, adjust the psychological state of patients, and maximize the compliance of patients with occlusal function exercise.PMID:38583035 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Yan Zhao Ying Zhang Qian Chen Li-Li Hou Source Type: research

Effect of different cleaning methods on bond strength and surface wettability of high translucency zirconia
CONCLUSIONS: Airborne-particle abrasion, cleaning paste and atmospheric pressure cold plasma overcome the effects of saliva contamination, producing the shear bond strength to zirconia similar to the control group. The atmospheric pressure cold plasma improves hydrophilicity of high translucency zirconia significantly.PMID:38583022 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Ji-Lan Jiao Xin-Yi Ye Lu Deng Hui Jiang Xiao-Xia Li Li-Wei Zeng Jian-Guo Tan Source Type: research

Downregulation of SETDB1 suppresses epithelial mesenchymal transition and invasion and metastasis in oral cancer via SOX7 methylation
CONCLUSIONS: Downregulation of SETDB1 could suppress EMT, migration and invasion of oral cancer cells by regulating SOX7 methylation level, providing new ideas and targets for the diagnosis and treatment of oral cancer.PMID:38583021 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Yan Hao Xiang-Yu Bai Feng Huo Xi-Bo Chen Source Type: research

The role of ROS/JNK/caspase 3 axis in apoptosis induction by menthol-favored electronic cigarette liquid in human periodontal ligament stem cells
CONCLUSIONS: ROS/JNK/caspase 3 axis is involved in menthol-favored E-liquid-induced apoptosis of hPDLSCs.PMID:38583023 (Source: Shanghai Journal of Stomatology)
Source: Shanghai Journal of Stomatology - April 7, 2024 Category: Dentistry Authors: Yi-Fen Shen Chao Liu Ying Tang Tao Yang Yong-Chun Gu Source Type: research