Patient with unusually severe infection reveals a rare type of immune deficiency
(Rockefeller University) A rare genetic change may explain why some people die from cytomegalovirus, a stealth pathogen that is often asymptomatic. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 29, 2020 Category: Infectious Diseases Source Type: news
Cytomegalovirus seropositivity and suicidal behavior: a mini-review - Paolini M, Lester D, Hawkins M, Hawkins-Villarreal A, Erbuto D, Fiorillo A, Pompili M.
Background and objectives: In recent years, a growing body of research has focused on identifying possible biological markers for suicidal behavior, including infective and immunological markers. In this paper, our aim was to review available eviden... (Source: SafetyLit)
Source: SafetyLit - December 19, 2019 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Dangerous bone marrow, organ transplant complication explained
(Oregon Health& Science University) Scientists have discovered the molecular mechanism behind how the common cytomegalovirus can wreak havoc on bone marrow and organ transplant patients, according to a paper published in the journal Cell& Host Microbe. The finding could help researchers develop better drugs to prevent related transplant complications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 19, 2019 Category: International Medicine & Public Health Source Type: news
Congenital viral infections in England over five decades: a population-based observational study
Study (data from 1968 to 2016) reports that compared with earlier years of the study, rates in 2016 were higher for congenital cytomegalovirus (CMV), herpes simplex virus, and varicella zoster virus, but lower for rubella. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 20, 2019 Category: Consumer Health News Source Type: news
Nivolumab (Opdivo): reports of cytomegalovirus (CMV) gastrointestinal infection or reactivation
This alert, based on a European review, advises that if patients on nivolumab present with diarrhoea or colitis, investigate possible causes, including infections; perform a stool infection work-up and screen for CMV. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 25, 2019 Category: Consumer Health News Source Type: news
OHSU receives grant from Gates Foundation to develop universal flu vaccine
Oregon Health& Science University received a grant from the Gates Foundation to develop the Holy Grail of vaccines: a universal flu vaccine.
OHSU is one of about six institutions that are splitting up to $12 million through the Grand Challenge for Universal Influenza Vaccine Development.
The basis for OHSU’s effort will be its cytomegalovirus platform, which it is already using to develop vaccines against HIV and tuberculosis. The i nfluenza virus would be inserted into the CMV vector to stimulate… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - August 29, 2019 Category: Pharmaceuticals Authors: Elizabeth Hayes Source Type: news
OHSU receives grant from Gates Foundation to develop universal flu vaccine
Oregon Health& Science University received a grant from the Gates Foundation to develop the Holy Grail of vaccines: a universal flu vaccine.
OHSU is one of about six institutions that are splitting up to $12 million through the Grand Challenge for Universal Influenza Vaccine Development.
The basis for OHSU’s effort will be its cytomegalovirus platform, which it is already using to develop vaccines against HIV and tuberculosis. The i nfluenza virus would be inserted into the CMV vector to stimulate… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - August 29, 2019 Category: Biotechnology Authors: Elizabeth Hayes Source Type: news
HIV vaccine nears clinical trial following new findings
A promising vaccine that clears an HIV-like virus from monkeys is closer to human testing after a new, weakened version of the vaccine has been shown to provide similar protection as its original version. A pair of papers published July 17 in Science Translational Medicine describe how the vaccine - which uses a form of the common herpes virus cytomegalovirus, or CMV - was live-attenuated, or weakened so CMV couldn't spread as easily. (Source: World Pharma News)
Source: World Pharma News - July 24, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
HIV vaccine nears clinical trial following new findings
(Oregon Health& Science University) A promising vaccine that clears an HIV-like virus from monkeys is closer to human testing after a new, weakened version of the vaccine has been shown to provide similar protection as its original version. The vaccine -- which uses a form of the common herpes virus cytomegalovirus, or CMV -- was live-attenuated, or weakened so CMV couldn't spread as easily. Having an attenuated version of the vaccine is key to being potentially able to use it in humans. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 17, 2019 Category: Infectious Diseases Source Type: news
Simple Blood Draw Detects Dangerous Pathogens
Liquid biopsy has attracted a surge of companies that are trying to change the way cancer is detected and monitored. But the benefits of this new type of technology can - and should - seep into other disease categories.
Redwood City, CA-based Karius, for example, is leveraging liquid biopsy technology to give doctors an upper hand on difficult-to-diagnose infectious diseases. New findings show the potential clinical utility of its the Karius Test to detect pathogens causing serious infections using a simple blood draw. This includes pathogens that are otherwise difficult to culture or identify witho...
Source: MDDI - June 26, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: IVD Source Type: news
What Infectious Diseases are Important to Consider in Transplantation Patients?
Discussion
Transplantation is not a common problem for primary care physicians but when a child’s disease has progressed to end-stage organ failure, transplantation can be the only treatment available. While the primary care provider usually is not involved in the daily management of patients before, during and after transplantation, they can be involved in many areas. These can include providing appropriate primary and acute care, ordering and obtaining necessary medical tests, medications and equipment, assisting with medical insurance, providing medical history and records to consultants, translating medical infor...
Source: PediatricEducation.org - June 24, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Cytomegalovirus Linked to Faster Progression of Cystic Fibrosis
Faster progression to end - stage lung disease observed among patients with CMV IgG positivity (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - April 11, 2019 Category: Respiratory Medicine Tags: Infections, Pulmonology, Journal, Source Type: news
Cytomegalovirus Linked to Faster Progression of Cystic Fibrosis
THURSDAY, April 11, 2019 -- For patients with cystic fibrosis (CF), cytomegalovirus (CMV) is associated with faster disease progression, according to a research letter published online April 7 in the European Respiratory Journal.
Michael D. Parkins,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 11, 2019 Category: Pharmaceuticals Source Type: news
New research unit approved
(University of W ü rzburg) A new international research group aims to develop new approaches to prevent and treat cytomegalovirus infection. Lars D ö lken, a virology expert from W ü rzburg, is the research unit's spokesman. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 10, 2019 Category: Infectious Diseases Source Type: news
Common virus is 'less prone to mutation' giving hope for vaccine development
(University College London) One of the commonest causes of congenital disability, the Human Cytomegalovirus (HCMV), is less prone to mutation than previously thought, a finding which could help develop a successful vaccine, UCL researchers have found. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 25, 2019 Category: Infectious Diseases Source Type: news
