Serous cystic neoplasm of pancreas with surgical obstructive jaundice and double duct sign: Cystadenoma or cystadenocarcinoma?
(Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - April 18, 2024 Category: Gastroenterology Source Type: research
Familial syndromes associated with testicular and paratesticular neoplasms: a comprehensive review
AbstractA syndromic association between a subset of testicular/paratesticular neoplasms is well established. Such examples include Carney complex and large cell calcifying Sertoli cell tumor, Peutz-Jeghers syndrome and intratubular large cell hyalinizing Sertoli cell neoplasia, and VHL syndrome and clear cell papillary cystadenoma of the epididymis.However, recent studies proposed potential novel links between some testicular and paratesticular neoplasms with certain tumor syndromes. While more studies are still needed to solidify these associations, recent research suggests that a subset of Leydig cell tumors may arise in...
Source: Virchows Archiv - April 15, 2024 Category: Pathology Source Type: research
Cancers, Vol. 16, Pages 1446: Ovarian Causes of Pseudomyxoma Peritonei (PMP) & mdash;A Literature Review
Conclusions. In our study, we aimed to provide a comprehensive overview of the ovarian causes of pseudomyxoma peritonei, including its epidemiology, imagery characteristics, symptoms, current treatment, and promising future therapies, in the hopes of finding feasible solutions, as a lack of understanding of this mucus-secreting malignant disease increases the risk of delayed diagnosis or uncontrolled deterioration. (Source: Cancers)
Source: Cancers - April 9, 2024 Category: Cancer & Oncology Authors: Sinziana Ionescu Marian Marincas Octavia Luciana Madge Irinel Gabriel Dicu-Andreescu Elena Chitoran Vlad Rotaru Ciprian Cirimbei Mirela Gherghe Adina Ene Robert Rosca Madalina Radu Laurentiu Simion Tags: Review Source Type: research
Oncocytic papillary cystadenoma of the larynx: a case report
ConclusionEctopic minor salivary gland tumors, both benign and malignant, should be taken into consideration as potential differential diagnosis for any swelling arising within the upper digestive tract mucosa. Ears, nose, and throat clinical examination completed by videolaryngoscopy can easily point out the location of the mass. Imaging is mandatory for differential diagnosis and for surgical planning. Surgical excision can provide both diagnosis and definitive cure. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - March 20, 2024 Category: General Medicine Source Type: research
Correlation between plasma PSGL ‐1 and FIGO stage, tumor metastasis, and survival in epithelial ovarian cancer
AbstractPlasma circulating P-selectin glycoprotein ligand-1 (PSGL-1) levels and its clinical correlation in patients with epithelial ovarian cancer (EOC) are unknown. The study determined plasma PSGL-1 levels in EOC patients and investigated its relationship with clinicopathological factors and prognosis. Plasma PSGL-1 levels were measured using ELISA in 69 patients with EOC, 34 patients with benign ovarian cystadenoma, and 36 healthy controls. Subsequently, the relationship between PSGL-1 levels and clinicopathological characteristics of patients, as well as the prognosis of EOC patients, was examined. Additionally, the s...
Source: Biotechnology and Applied Biochemistry - March 18, 2024 Category: Biochemistry Authors: WenHui Li,
Cheng Fang,
Ya Gao,
Yan Gao,
FengShang Yan,
BiLiang Chen,
MingJuan Xu Tags: ORIGINAL ARTICLE Source Type: research
Benign Brenner tumor of the ovary: two-dimensional and contrast-enhanced ultrasound features —a retrospective study from a single center
ConclusionsBBT can show ovarian cystic, mixed cystic and solid type, and solid echo in 2D ultrasound. Unilateral ovarian fibrosis with punctate calcification is an important feature of BBT in 2D ultrasound. However, for solid adnexal masses and mixed cystic and solid masses with unclear diagnosis, if CEUS shows isoenhancement or hyperenhancement, the possibility of BBT cannot be excluded. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 8, 2024 Category: Cancer & Oncology Source Type: research
Revisiting the performance of cyst fluid carcinoembryonic antigen as a diagnostic marker for pancreatic mucinous cysts: a comprehensive 20-year institutional review
Conclusion
Cyst fluid CEA continues to be a useful test in the diagnosis of mucinous pancreatic cysts but does not appear as specific as previously reported. Raising the CEA threshold to 250 ng/mL to maintain specificity for differentiating mucinous from non-mucinous cysts may be considered. (Source: Gut)
Source: Gut - March 7, 2024 Category: Gastroenterology Authors: Kwan, M. C., Pitman, M. B., Fernandez-del Castillo, C., Zhang, M. L. Tags: Gut Pancreas Source Type: research
Belzutifan for von Hippel-Lindau Disease: Pancreatic Lesion Population of the Phase 2 LITESPARK-004 Study
CONCLUSIONS: Belzutifan continued to show robust activity and manageable safety in VHL disease-associated pNETs.PMID:38393723 | DOI:10.1158/1078-0432.CCR-23-2592 (Source: Cell Research)
Source: Cell Research - February 23, 2024 Category: Cytology Authors: Tobias Else Eric Jonasch Othon Lliopoulos Kathryn E Beckermann Vivek Narayan Benjamin L Maughan Stephane Oudard Jodi K Maranchie Ane B Iversen Cynthia Muller Goldberg Wei Fu Rodolfo F Perini Yanfang Liu W Marston Linehan Ramaprasad Srinivasan Source Type: research
Belzutifan for von Hippel-Lindau Disease: Pancreatic Lesion Population of the Phase 2 LITESPARK-004 Study
CONCLUSIONS: Belzutifan continued to show robust activity and manageable safety in VHL disease-associated pNETs.PMID:38393723 | DOI:10.1158/1078-0432.CCR-23-2592 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - February 23, 2024 Category: Cancer & Oncology Authors: Tobias Else Eric Jonasch Othon Lliopoulos Kathryn E Beckermann Vivek Narayan Benjamin L Maughan Stephane Oudard Jodi K Maranchie Ane B Iversen Cynthia Muller Goldberg Wei Fu Rodolfo F Perini Yanfang Liu W Marston Linehan Ramaprasad Srinivasan Source Type: research
CK7+/CK20+/CDX2+ mucinous carcinoma, arising in a mature cystic teratoma of ovary, presenting with disseminated metastasis and pseudomyxoma peritonei
In this report, we have described a case of a well-differentiated mucinous carcinoma arising within a mature cystic teratoma. The mucinous carcinoma showed a spectrum of morphological patterns, including cystadenoma-like areas, proliferative/borderline areas, villous adenoma-like areas, and areas of invasive carcinoma. In addition, our case showed some unusual findings, namely, diffuse CK7 positivity, associated pseudomyxoma peritonei, and metastasis to lungs. These features were not demonstrated in any of the previously reported cases. Our case shows that the teratomatous mucinous neoplasm of the ovary may show CK7+/CK20+...
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Amit K Adhya Abhitesh Singh Dillip K Muduly Biswajit Sahoo Source Type: research
Belzutifan for von Hippel-Lindau Disease: Pancreatic Lesion Population of the Phase 2 LITESPARK-004 Study
CONCLUSIONS: Belzutifan continued to show robust activity and manageable safety in VHL disease-associated pNETs.PMID:38393723 | DOI:10.1158/1078-0432.CCR-23-2592 (Source: Cell Research)
Source: Cell Research - February 23, 2024 Category: Cytology Authors: Tobias Else Eric Jonasch Othon Lliopoulos Kathryn E Beckermann Vivek Narayan Benjamin L Maughan Stephane Oudard Jodi K Maranchie Ane B Iversen Cynthia Muller Goldberg Wei Fu Rodolfo F Perini Yanfang Liu W Marston Linehan Ramaprasad Srinivasan Source Type: research
Belzutifan for von Hippel-Lindau Disease: Pancreatic Lesion Population of the Phase 2 LITESPARK-004 Study
CONCLUSIONS: Belzutifan continued to show robust activity and manageable safety in VHL disease-associated pNETs.PMID:38393723 | DOI:10.1158/1078-0432.CCR-23-2592 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - February 23, 2024 Category: Cancer & Oncology Authors: Tobias Else Eric Jonasch Othon Lliopoulos Kathryn E Beckermann Vivek Narayan Benjamin L Maughan Stephane Oudard Jodi K Maranchie Ane B Iversen Cynthia Muller Goldberg Wei Fu Rodolfo F Perini Yanfang Liu W Marston Linehan Ramaprasad Srinivasan Source Type: research
CK7+/CK20+/CDX2+ mucinous carcinoma, arising in a mature cystic teratoma of ovary, presenting with disseminated metastasis and pseudomyxoma peritonei
In this report, we have described a case of a well-differentiated mucinous carcinoma arising within a mature cystic teratoma. The mucinous carcinoma showed a spectrum of morphological patterns, including cystadenoma-like areas, proliferative/borderline areas, villous adenoma-like areas, and areas of invasive carcinoma. In addition, our case showed some unusual findings, namely, diffuse CK7 positivity, associated pseudomyxoma peritonei, and metastasis to lungs. These features were not demonstrated in any of the previously reported cases. Our case shows that the teratomatous mucinous neoplasm of the ovary may show CK7+/CK20+...
Source: Indian Journal of Pathology and Microbiology - February 23, 2024 Category: Pathology Authors: Amit K Adhya Abhitesh Singh Dillip K Muduly Biswajit Sahoo Source Type: research
