Hustle and bustle at ICE/ENDO 2014
I arrived at McCormick Place to find all the usual hustle and bustle associated with ENDO. I queued, picked up my chic (!) backpack and rushed off to hang my poster. I also had a chance to take a peak at the history of endocrinology timeline as the Endocrine Society approaches it's centenary.
ENDO2014 was officially kicked off yesterday by Robert Lefkowitz who gave us an insightful tour through his lifetime's research on seven transmembrane receptors. His more recent discoveries on B-arrestins were fascinating. I bumped into Sam Mirczuk, Chair of the YE committee in this session :)
John Newell-P...
Source: Society for Endocrinology - July 2, 2014 Category: Endocrinology Source Type: news
Cushing Syndrome
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 20, 2014 Category: Journals (General) Source Type: news
Response in Cushing's Syndrome Treated With Mifepristone Response in Cushing's Syndrome Treated With Mifepristone
What are strong drivers of response to mifepristone therapy in patients with Cushing disease? Clinical Endocrinology (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 10, 2014 Category: Endocrinology Tags: Diabetes & Endocrinology Journal Article Source Type: news
Diagnosis and Differential Diagnosis of Cushing's SyndromeDiagnosis and Differential Diagnosis of Cushing's Syndrome
Read about the misadventures in diagnosis of this Cushingoid patient. Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 17, 2014 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Cushing's syndrome: A genetic basis for cortisol excess
An international team of researchers led by an endocrinologist at Ludwig-Maximilians-Universitaet (LMU) in Munich has identified genetic mutations that result in uncontrolled synthesis and secretion of the stress hormone cortisol. Cortisol is a hormone that is produced by the adrenal gland in response to stressful events, and modulates a whole spectrum of physiological processes. An international research collaboration has now identified genetic mutations that lead to the production and secretion of cortisol in the absence of an underlying stressor. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 28, 2014 Category: Consumer Health News Tags: Endocrinology Source Type: news
Cushing's syndrome: Genetic basis for cortisol excess
Cushing’s syndrome has been found to be linked to a genetic basis for cortisol excess. Cortisol is a hormone that is produced by the adrenal gland in response to stressful events, and modulates a whole spectrum of physiological processes. An international research collaboration has now identified genetic mutations that lead to the production and secretion of cortisol in the absence of an underlying stressor. This condition, known as Cushing's syndrome, can be successfully treated by surgical removal of the affected adrenal gland. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 27, 2014 Category: Science Source Type: news
NIH researchers identify mutation linked to severe form of Cushing's syndrome
Mutation in related gene found in patient with Carney Complex. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - February 27, 2014 Category: American Health Source Type: news
Well: Think Like a Doctor: Red Herrings Solved!
Readers solve the case of a 29-year-old woman with an injured groin, a swollen foot and long list of other abnormalities. (Source: NYT)
Source: NYT - January 18, 2014 Category: American Health Authors: By LISA SANDERS, M.D. Tags: Cushing's Syndrome Doctors Hormones Think Like a Doctor ACTH (Adrenocorticotropic Hormone) Featured Cortisol (Hormone) Source Type: news
Genetic screening to find 'silent carriers' of adrenal Cushing's syndrome
Genetic research published in the New England Journal of Medicine suggests to Dr. Andre Lacroix, professor at the University of Montreal, that clinicians' understanding and treatment of a form of Cushing's syndrome affecting both adrenal glands will be fundamentally changed, and that moreover, it might be appropriate to begin screening for the genetic mutations that cause this form of the disease. "Screening family members of bilateral adrenal Cushing's syndrome patients with genetic mutations may identify affected silent carriers," Lacroix said in an editorial in this Journal. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 2, 2013 Category: Consumer Health News Tags: Genetics Source Type: news
Genetic Studies Shed Light on Cushing's Syndrome
(MedPage Today) -- Some cases of corticotropin-independent macronodular adrenal hyperplasia occur as a result of inactivating mutations in what appears to be a tumor-suppressor gene, a study reported, while another group of researchers found that the disease may be regulated by corticotropin. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - December 1, 2013 Category: Endocrinology Source Type: news
Two Copies of Mutant Gene May Trigger Rare Adrenal Disorder
Source: National Institute of Child Health and Human Development -
Related MedlinePlus Page: Cushing's Syndrome (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 29, 2013 Category: Consumer Health News Source Type: news
New Studies Shed Light on Cushing's SyndromeNew Studies Shed Light on Cushing's Syndrome
Two early research studies have identified a gene mutation and abnormal receptors in the adrenal gland that are implicated in Cushing's syndrome and might lead to future screening and treatment strategies. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 29, 2013 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
Abortion Drug Aids in Cushing's Syndrome (CME/CE)
(MedPage Today) -- Treatment of patients with refractory Cushing's syndrome using the glucocorticoid receptor antagonist mifepristone led to improvements in global clinical response, a post-hoc analysis found. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 23, 2013 Category: Cardiology Source Type: news
MR Brain Spectroscopy Detects Damage In The Hippocampus Of Patients Exposed To Excess Cortisol
New research shows that patients who are "biochemically cured" of Cushing's syndrome have levels of brain metabolites which are associated with neural damage. This will have implications for treatment of Cushing's patients, but might also suggest that patients using high levels of glucocorticoid drugs may suffer similar long-term problems. The work was presented yesterday at the European Congress of Endocrinology in Copenhagen. Cushing's syndrome is an endocrine disease causing an overproduction of the stress hormone cortisol... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 2, 2013 Category: Consumer Health News Tags: Endocrinology Source Type: news
Korlym (Mifepristone) for Treatment of Endogenous Cushing’s Syndrome
Korlym (mifepristone) is a glucocorticoid receptor blocker indicated for the control of high blood sugar levels in adult patients suffering from endogenous Cushing's syndrome. (Source: Drug Development Technology)
Source: Drug Development Technology - April 25, 2013 Category: Pharmaceuticals Source Type: news
