Effect of < em > Nigella sativa < /em > on Selected Gastrointestinal Diseases
Curr Issues Mol Biol. 2023 Apr 3;45(4):3016-3034. doi: 10.3390/cimb45040198.ABSTRACTNigella sativa L. (family Ranunculaceae), also known as black cumin, has been used in cuisine around the world for many years. Due to its health-promoting properties, it can be used not only in the food industry but also in medicine. The main bioactive compound contained in the black cumin extract is thymoquinone (TQ), which has a special therapeutic role. The results of research in recent years confirmed its hypoglycemic, hypolipemic, and hepatoprotective effects, among others. In addition, the results of laboratory tests also indicate its...
Source: Current Issues in Molecular Biology - May 15, 2023 Category: Molecular Biology Authors: Sara Jarmakiewicz-Czaja Magdalena Zieli ńska Kacper Helma Aneta Sokal Rafa ł Filip Source Type: research

Effect of < em > Nigella sativa < /em > on Selected Gastrointestinal Diseases
Curr Issues Mol Biol. 2023 Apr 3;45(4):3016-3034. doi: 10.3390/cimb45040198.ABSTRACTNigella sativa L. (family Ranunculaceae), also known as black cumin, has been used in cuisine around the world for many years. Due to its health-promoting properties, it can be used not only in the food industry but also in medicine. The main bioactive compound contained in the black cumin extract is thymoquinone (TQ), which has a special therapeutic role. The results of research in recent years confirmed its hypoglycemic, hypolipemic, and hepatoprotective effects, among others. In addition, the results of laboratory tests also indicate its...
Source: Current Issues in Molecular Biology - May 15, 2023 Category: Molecular Biology Authors: Sara Jarmakiewicz-Czaja Magdalena Zieli ńska Kacper Helma Aneta Sokal Rafa ł Filip Source Type: research

Effect of < em > Nigella sativa < /em > on Selected Gastrointestinal Diseases
Curr Issues Mol Biol. 2023 Apr 3;45(4):3016-3034. doi: 10.3390/cimb45040198.ABSTRACTNigella sativa L. (family Ranunculaceae), also known as black cumin, has been used in cuisine around the world for many years. Due to its health-promoting properties, it can be used not only in the food industry but also in medicine. The main bioactive compound contained in the black cumin extract is thymoquinone (TQ), which has a special therapeutic role. The results of research in recent years confirmed its hypoglycemic, hypolipemic, and hepatoprotective effects, among others. In addition, the results of laboratory tests also indicate its...
Source: Current Issues in Molecular Biology - May 15, 2023 Category: Molecular Biology Authors: Sara Jarmakiewicz-Czaja Magdalena Zieli ńska Kacper Helma Aneta Sokal Rafa ł Filip Source Type: research

Effect of < em > Nigella sativa < /em > on Selected Gastrointestinal Diseases
Curr Issues Mol Biol. 2023 Apr 3;45(4):3016-3034. doi: 10.3390/cimb45040198.ABSTRACTNigella sativa L. (family Ranunculaceae), also known as black cumin, has been used in cuisine around the world for many years. Due to its health-promoting properties, it can be used not only in the food industry but also in medicine. The main bioactive compound contained in the black cumin extract is thymoquinone (TQ), which has a special therapeutic role. The results of research in recent years confirmed its hypoglycemic, hypolipemic, and hepatoprotective effects, among others. In addition, the results of laboratory tests also indicate its...
Source: Current Issues in Molecular Biology - May 15, 2023 Category: Molecular Biology Authors: Sara Jarmakiewicz-Czaja Magdalena Zieli ńska Kacper Helma Aneta Sokal Rafa ł Filip Source Type: research

Molecular mechanisms and signaling pathways of black cumin (Nigella sativa) and its active constituent, thymoquinone: a review
CONCLUSIONS: Taken together, the improvement of antioxidant status and prevention of inflammatory process by modulating the Nrf2 and NF-κB signaling and inhibition of cancer cell proliferation through disruption of the PI3K/AKT pathway appear to be the main mechanisms involved in different pharmacological properties of N. sativa and thymoquinone.PMID:37155017 | DOI:10.1007/s11033-023-08363-y (Source: Mol Biol Cell)
Source: Mol Biol Cell - May 8, 2023 Category: Molecular Biology Authors: Ehsan Sadeghi Mohsen Imenshahidi Hossein Hosseinzadeh Source Type: research

Molecular mechanisms and signaling pathways of black cumin (Nigella sativa) and its active constituent, thymoquinone: a review
CONCLUSIONS: Taken together, the improvement of antioxidant status and prevention of inflammatory process by modulating the Nrf2 and NF-κB signaling and inhibition of cancer cell proliferation through disruption of the PI3K/AKT pathway appear to be the main mechanisms involved in different pharmacological properties of N. sativa and thymoquinone.PMID:37155017 | DOI:10.1007/s11033-023-08363-y (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - May 8, 2023 Category: Molecular Biology Authors: Ehsan Sadeghi Mohsen Imenshahidi Hossein Hosseinzadeh Source Type: research

Molecular mechanisms and signaling pathways of black cumin (Nigella sativa) and its active constituent, thymoquinone: a review
CONCLUSIONS: Taken together, the improvement of antioxidant status and prevention of inflammatory process by modulating the Nrf2 and NF-κB signaling and inhibition of cancer cell proliferation through disruption of the PI3K/AKT pathway appear to be the main mechanisms involved in different pharmacological properties of N. sativa and thymoquinone.PMID:37155017 | DOI:10.1007/s11033-023-08363-y (Source: Mol Biol Cell)
Source: Mol Biol Cell - May 8, 2023 Category: Molecular Biology Authors: Ehsan Sadeghi Mohsen Imenshahidi Hossein Hosseinzadeh Source Type: research

Molecular mechanisms and signaling pathways of black cumin (Nigella sativa) and its active constituent, thymoquinone: a review
CONCLUSIONS: Taken together, the improvement of antioxidant status and prevention of inflammatory process by modulating the Nrf2 and NF-κB signaling and inhibition of cancer cell proliferation through disruption of the PI3K/AKT pathway appear to be the main mechanisms involved in different pharmacological properties of N. sativa and thymoquinone.PMID:37155017 | DOI:10.1007/s11033-023-08363-y (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - May 8, 2023 Category: Molecular Biology Authors: Ehsan Sadeghi Mohsen Imenshahidi Hossein Hosseinzadeh Source Type: research

Studying the actions of sage and thymoquinone combination on metabolic syndrome induced by high-fat diet in rats
CONCLUSIONS: The results of the current study verified that sage essential oil, together with TQ exhibited hypoglycemic, hypolipidemic, and antioxidant actions and thus could be a valuable addition to diabetes management.PMID:37013759 | DOI:10.26355/eurrev_202303_31775 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 4, 2023 Category: Drugs & Pharmacology Authors: S M Alanazi R A Alsaqer F I Alsaeed R M Almakhaytah N T Buwashl M E Mohamed N S Younis Source Type: research

Studying the actions of sage and thymoquinone combination on metabolic syndrome induced by high-fat diet in rats
CONCLUSIONS: The results of the current study verified that sage essential oil, together with TQ exhibited hypoglycemic, hypolipidemic, and antioxidant actions and thus could be a valuable addition to diabetes management.PMID:37013759 | DOI:10.26355/eurrev_202303_31775 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 4, 2023 Category: Drugs & Pharmacology Authors: S M Alanazi R A Alsaqer F I Alsaeed R M Almakhaytah N T Buwashl M E Mohamed N S Younis Source Type: research

Studying the actions of sage and thymoquinone combination on metabolic syndrome induced by high-fat diet in rats
CONCLUSIONS: The results of the current study verified that sage essential oil, together with TQ exhibited hypoglycemic, hypolipidemic, and antioxidant actions and thus could be a valuable addition to diabetes management.PMID:37013759 | DOI:10.26355/eurrev_202303_31775 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 4, 2023 Category: Drugs & Pharmacology Authors: S M Alanazi R A Alsaqer F I Alsaeed R M Almakhaytah N T Buwashl M E Mohamed N S Younis Source Type: research

Studying the actions of sage and thymoquinone combination on metabolic syndrome induced by high-fat diet in rats
CONCLUSIONS: The results of the current study verified that sage essential oil, together with TQ exhibited hypoglycemic, hypolipidemic, and antioxidant actions and thus could be a valuable addition to diabetes management.PMID:37013759 | DOI:10.26355/eurrev_202303_31775 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 4, 2023 Category: Drugs & Pharmacology Authors: S M Alanazi R A Alsaqer F I Alsaeed R M Almakhaytah N T Buwashl M E Mohamed N S Younis Source Type: research

Studying the actions of sage and thymoquinone combination on metabolic syndrome induced by high-fat diet in rats
CONCLUSIONS: The results of the current study verified that sage essential oil, together with TQ exhibited hypoglycemic, hypolipidemic, and antioxidant actions and thus could be a valuable addition to diabetes management.PMID:37013759 | DOI:10.26355/eurrev_202303_31775 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 4, 2023 Category: Drugs & Pharmacology Authors: S M Alanazi R A Alsaqer F I Alsaeed R M Almakhaytah N T Buwashl M E Mohamed N S Younis Source Type: research

Studying the actions of sage and thymoquinone combination on metabolic syndrome induced by high-fat diet in rats
CONCLUSIONS: The results of the current study verified that sage essential oil, together with TQ exhibited hypoglycemic, hypolipidemic, and antioxidant actions and thus could be a valuable addition to diabetes management.PMID:37013759 | DOI:10.26355/eurrev_202303_31775 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 4, 2023 Category: Drugs & Pharmacology Authors: S M Alanazi R A Alsaqer F I Alsaeed R M Almakhaytah N T Buwashl M E Mohamed N S Younis Source Type: research

Studying the actions of sage and thymoquinone combination on metabolic syndrome induced by high-fat diet in rats
CONCLUSIONS: The results of the current study verified that sage essential oil, together with TQ exhibited hypoglycemic, hypolipidemic, and antioxidant actions and thus could be a valuable addition to diabetes management.PMID:37013759 | DOI:10.26355/eurrev_202303_31775 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 4, 2023 Category: Drugs & Pharmacology Authors: S M Alanazi R A Alsaqer F I Alsaeed R M Almakhaytah N T Buwashl M E Mohamed N S Younis Source Type: research