Therapeutic and Phytochemical Properties of Thymoquinone Derived from Nigella Sativa
CONCLUSION: TQ seems to have a variety of consequences on how infected cells behave at the cellular level.PMID:37605475 | DOI:10.2174/2589977515666230811092410 (Source: Cell Research)
Source: Cell Research - August 22, 2023 Category: Cytology Authors: Gaurav Tiwari Monisha Gupta Lalchand D Devhare Ruchi Tiwari Source Type: research
Black cumin ethanolic extract reduce aortic intima media thickness due to cigarette smoke exposure in experimental rats
Background and Aims: Cigarette smoking could induce pro-atherogenic changes seen in endothelial cells and increase inflammation markers due to oxidative stress. This can lead to increased intima media thickness of blood vessel and accelerate atherosclerosis. Black cumin (Nigella sativa) may inhibit oxidative stress. Aim of this study is to explore the link between cigarette smoking exposure to endothelial-nitric oxide synthase and vascular cell adhesion molecule-1 as well as the protective effects of black cumin in reducing aortic intima media thickness caused by cigarette smoking. (Source: Atherosclerosis)
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: R.A. Nugraha, B.P. Khrisna, T. Putra, L.G. Rinjani, M. Ardiana, I.G. Suryawan, B. Pikir Source Type: research
Using days alive and out of hospital to measure surgical outcomes in New Zealand: a cross-sectional study
Conclusion
In New Zealand after direct risk adjustment, differences in DAOH90 between three types of surgical procedure reflected their respective risk levels and associated mortality rates. Outlier DHBs were identified for each procedure. Thus, our approach to analysing DAOH90 appears to have considerable face validity and potential utility for contributing to the measurement of perioperative outcomes in an audit or quality improvement setting. (Source: BMJ Open)
Source: BMJ Open - July 25, 2023 Category: General Medicine Authors: Boyle, L., Lumley, T., Cumin, D., Campbell, D., Merry, A. F. Tags: Open access, Surgery Source Type: research
Activity of cumin essential oil to control fascioliasis: Efficacy and changes in the tegument of Fasciola hepatica
In this study, we aimed to evaluate the efficacy of cumin (Cuminum cyminum) essential oil against F. hepatica eggs and adults. The eggs were incubated with eight concentrations of the essential oil (0.031125-4.15 mg/mL), and viable eggs were counted after 14 days and classified as embryonated or non-embryonated. Adult flukes were incubated in Roswell Park Memorial Institute medium to ensure their viability and then incubated in essential oil. They were observed for 24 h after treatment. The adults were assessed with the two lowest effective oil concentrations used in the ovicidal test. Three controls were used for both tes...
Source: Experimental Parasitology - July 16, 2023 Category: Parasitology Authors: Alexia Brauner de Mello Bruna Baccega Filipe Obelar Martins Ivandra Ign ês de Santi Yan Wahast Islab ão Marjorie de Giacometi Mauro Pereira Soares Nara Am élia da Rosa Farias Camila Belmonte de Oliveira Source Type: research
Activity of cumin essential oil to control fascioliasis: Efficacy and changes in the tegument of Fasciola hepatica
In this study, we aimed to evaluate the efficacy of cumin (Cuminum cyminum) essential oil against F. hepatica eggs and adults. The eggs were incubated with eight concentrations of the essential oil (0.031125-4.15 mg/mL), and viable eggs were counted after 14 days and classified as embryonated or non-embryonated. Adult flukes were incubated in Roswell Park Memorial Institute medium to ensure their viability and then incubated in essential oil. They were observed for 24 h after treatment. The adults were assessed with the two lowest effective oil concentrations used in the ovicidal test. Three controls were used for both tes...
Source: Experimental Parasitology - July 16, 2023 Category: Parasitology Authors: Alexia Brauner de Mello Bruna Baccega Filipe Obelar Martins Ivandra Ign ês de Santi Yan Wahast Islab ão Marjorie de Giacometi Mauro Pereira Soares Nara Am élia da Rosa Farias Camila Belmonte de Oliveira Source Type: research
Activity of cumin essential oil to control fascioliasis: Efficacy and changes in the tegument of Fasciola hepatica
In this study, we aimed to evaluate the efficacy of cumin (Cuminum cyminum) essential oil against F. hepatica eggs and adults. The eggs were incubated with eight concentrations of the essential oil (0.031125-4.15 mg/mL), and viable eggs were counted after 14 days and classified as embryonated or non-embryonated. Adult flukes were incubated in Roswell Park Memorial Institute medium to ensure their viability and then incubated in essential oil. They were observed for 24 h after treatment. The adults were assessed with the two lowest effective oil concentrations used in the ovicidal test. Three controls were used for both tes...
Source: Experimental Parasitology - July 16, 2023 Category: Parasitology Authors: Alexia Brauner de Mello Bruna Baccega Filipe Obelar Martins Ivandra Ign ês de Santi Yan Wahast Islab ão Marjorie de Giacometi Mauro Pereira Soares Nara Am élia da Rosa Farias Camila Belmonte de Oliveira Source Type: research
Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective
Adv Exp Med Biol. 2023;1412:375-395. doi: 10.1007/978-3-031-28012-2_20.ABSTRACTIn the face of the COVID-19 pandemic, many people around the world have increased their healthy behaviors to prevent transmission of the virus and potentially improve their immune systems. Therefore, the role of diet and food compounds such as spices with bioactive and antiviral properties may be important in these efforts. In this chapter, we review the efficacy of spices such as turmeric (curcumin), cinnamon, ginger, black pepper, saffron, capsaicin, and cumin by investigating the effects of these compounds of COVID-19 disease severity biomark...
Source: Advances in Experimental Medicine and Biology - June 28, 2023 Category: Research Authors: Masha Shirani Shokoofeh Talebi Mehrnaz Shojaei Gholamreza Askari Mohammad Bagherniya Paul C Guest Thozhukat Sathyapalan Amirhossein Sahebkar Source Type: research
Molecules, Vol. 28, Pages 5007: Nigella sativa-Manganese Ferrite-Reduced Graphene Oxide-Based Nanomaterial: A Novel Adsorbent for Water Treatment
In this study, a novel nanohybrid composite was fabricated via the incorporation of manganese ferrite (MnFe2O4) nanoparticles into the integrated surface of reduced graphene oxide (rGO) and black cumin seeds (BC). The nanohybrid composite was prepared by a simple co-precipitation method and characterized by several spectroscopic and microscopic techniques. The characterization analysis revealed that the rGO-BC surface was decorated with the MnFe2O4. The strong chemical interaction (via electrostatic and H-bonding) between the integrated surface of rGO-BC and MnFe2O4 nanoparticles has been reported. The prepared composite w...
Source: Molecules - June 26, 2023 Category: Chemistry Authors: Nusrat Tara May Abdullah Abomuti F. M. Alshareef Omeima Abdullah Esam S. Allehyani Saif Ali Chaudhry Seungdae Oh Tags: Article Source Type: research
In vitro study of Nigella sativa and thymoquinone activity on endothelial activation and monocyte adhesion
CONCLUSIONS: NSO and TQ supplementation have anti-atherogenic properties and inhibit monocytes' adherence to HCAECs via down-regulation of ICAM-1 expression. NSO could potentially be incorporated in standard treatment regimens to prevent atherosclerosis and its related complications.PMID:37212154 | DOI:10.32725/jab.2023.006 (Source: Atherosclerosis)
Source: Atherosclerosis - May 22, 2023 Category: Cardiology Authors: Al'Aina Yuhainis Firus Khan Fahmi Mohtar Thuhairah Abdul Rahman Suhaila Abdul Muid Gabriele Ruth Anisah Froemming Hapizah Nawawi Source Type: research
Effect of < em > Nigella sativa < /em > on Selected Gastrointestinal Diseases
Curr Issues Mol Biol. 2023 Apr 3;45(4):3016-3034. doi: 10.3390/cimb45040198.ABSTRACTNigella sativa L. (family Ranunculaceae), also known as black cumin, has been used in cuisine around the world for many years. Due to its health-promoting properties, it can be used not only in the food industry but also in medicine. The main bioactive compound contained in the black cumin extract is thymoquinone (TQ), which has a special therapeutic role. The results of research in recent years confirmed its hypoglycemic, hypolipemic, and hepatoprotective effects, among others. In addition, the results of laboratory tests also indicate its...
Source: Current Issues in Molecular Biology - May 15, 2023 Category: Molecular Biology Authors: Sara Jarmakiewicz-Czaja Magdalena Zieli ńska Kacper Helma Aneta Sokal Rafa ł Filip Source Type: research
