Nanoemulsion and Nanogel Containing < em > Cuminum cyminum < /em > L Essential Oil: Antioxidant, Anticancer, Antibacterial, and Antilarval Properties
J Trop Med. 2023 Feb 6;2023:5075581. doi: 10.1155/2023/5075581. eCollection 2023.ABSTRACTCuminum cyminum L. is a widespread medicinal plant with a broad spectrum of biological activity. In the present study, the chemical structure of its essential oil was examined utilizing GC-MS analysis (gas chromatography-mass spectrometry). Then, a nanoemulsion dosage form was prepared with a droplet size and droplet size distribution (SPAN) of 121 ± 3 nm and 0.96. After that, the dosage form of the nanogel was prepared; the nanoemulsion was gelified by the addition of 3.0% carboxymethyl cellulose. In addition, the successful loading ...
Source: Journal of Tropical Medicine - February 16, 2023 Category: Tropical Medicine Authors: Razie Ranjbar Elham Zarenezhad Abbas Abdollahi Marjan Nasrizadeh Samira Firooziyan Najmeh Namdar Mahmoud Osanloo Source Type: research
ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis
Haematologica. 2023 Feb 16. doi: 10.3324/haematol.2022.282049. Online ahead of print.ABSTRACTSustained ANKRD26 expression associated with germline ANKRD26 mutations causes Thrombocytopenia 2 (THC2), an inherited platelet disorder associated with leukemia predisposition. Some patients also present with erythrocytosis and/or leukocytosis. Using multiple human-relevant in vitro models (cell lines, primary patient cells and patient-derived iPSCs) we demonstrate for the first time that ANKRD26 is expressed during the early steps of erythroid, megakaryocyte and granulocyte differentiation, and is necessary for progenitor prolife...
Source: Haematologica - February 16, 2023 Category: Hematology Authors: Francesca Basso-Valentina Alessandro Donada Vladimir T Manchev Manuel Lisetto Nathalie Balayn Jean Edouard Martin Delphine Muller Cecilia Paola Marin Oyarzun H élène Duparc Brahim Arkoun Alessandro Cumin Lionel Faivre Nathalie Droin Ida Biunno Alessandr Source Type: research
Nanoemulsion and Nanogel Containing < em > Cuminum cyminum < /em > L Essential Oil: Antioxidant, Anticancer, Antibacterial, and Antilarval Properties
J Trop Med. 2023 Feb 6;2023:5075581. doi: 10.1155/2023/5075581. eCollection 2023.ABSTRACTCuminum cyminum L. is a widespread medicinal plant with a broad spectrum of biological activity. In the present study, the chemical structure of its essential oil was examined utilizing GC-MS analysis (gas chromatography-mass spectrometry). Then, a nanoemulsion dosage form was prepared with a droplet size and droplet size distribution (SPAN) of 121 ± 3 nm and 0.96. After that, the dosage form of the nanogel was prepared; the nanoemulsion was gelified by the addition of 3.0% carboxymethyl cellulose. In addition, the successful loading ...
Source: Journal of Tropical Medicine - February 16, 2023 Category: Tropical Medicine Authors: Razie Ranjbar Elham Zarenezhad Abbas Abdollahi Marjan Nasrizadeh Samira Firooziyan Najmeh Namdar Mahmoud Osanloo Source Type: research
ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis
Haematologica. 2023 Feb 16. doi: 10.3324/haematol.2022.282049. Online ahead of print.ABSTRACTSustained ANKRD26 expression associated with germline ANKRD26 mutations causes Thrombocytopenia 2 (THC2), an inherited platelet disorder associated with leukemia predisposition. Some patients also present with erythrocytosis and/or leukocytosis. Using multiple human-relevant in vitro models (cell lines, primary patient cells and patient-derived iPSCs) we demonstrate for the first time that ANKRD26 is expressed during the early steps of erythroid, megakaryocyte and granulocyte differentiation, and is necessary for progenitor prolife...
Source: Haematologica - February 16, 2023 Category: Hematology Authors: Francesca Basso-Valentina Alessandro Donada Vladimir T Manchev Manuel Lisetto Nathalie Balayn Jean Edouard Martin Delphine Muller Cecilia Paola Marin Oyarzun H élène Duparc Brahim Arkoun Alessandro Cumin Lionel Faivre Nathalie Droin Ida Biunno Alessandr Source Type: research
Nanoemulsion and Nanogel Containing < em > Cuminum cyminum < /em > L Essential Oil: Antioxidant, Anticancer, Antibacterial, and Antilarval Properties
J Trop Med. 2023 Feb 6;2023:5075581. doi: 10.1155/2023/5075581. eCollection 2023.ABSTRACTCuminum cyminum L. is a widespread medicinal plant with a broad spectrum of biological activity. In the present study, the chemical structure of its essential oil was examined utilizing GC-MS analysis (gas chromatography-mass spectrometry). Then, a nanoemulsion dosage form was prepared with a droplet size and droplet size distribution (SPAN) of 121 ± 3 nm and 0.96. After that, the dosage form of the nanogel was prepared; the nanoemulsion was gelified by the addition of 3.0% carboxymethyl cellulose. In addition, the successful loading ...
Source: Journal of Tropical Medicine - February 16, 2023 Category: Tropical Medicine Authors: Razie Ranjbar Elham Zarenezhad Abbas Abdollahi Marjan Nasrizadeh Samira Firooziyan Najmeh Namdar Mahmoud Osanloo Source Type: research
