From kitchen to clinic: Pharmacotherapeutic potential of common spices in Indian cooking in age-related neurological disorders
Aging is described as an advanced time-related collection of changes that may negatively affect with the risk of several diseases or death. Aging is a main factor of several age-related neurological disorders, including neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, and dementia), stroke, neuroinflammation, neurotoxicity, brain tumors, oxidative stress, and reactive oxygen species (ROS). Currently available medications for age-related neurological disorders may lead to several side effects, such as headache, diarrhea, nausea, gastrointestinal (GI) diseases, dyskinesia, and hallucinosis. These day...
Source: Frontiers in Pharmacology - November 10, 2022 Category: Drugs & Pharmacology Source Type: research

Superior incident photon-to-current conversion efficiency of Mo-doped activated carbon supported CdS-sensitized solar cells
This study presents a new strategy to increase the solar cell efficiency of semiconductor-based solar cell structures using biowaste-based AC supported CdS semiconductor materials.PMID:36239891 | DOI:10.1007/s11356-022-23552-1 (Source: Environmental Science and Pollution Research International)
Source: Environmental Science and Pollution Research International - October 14, 2022 Category: Environmental Health Authors: Ebru Batur Sinan Kutluay Orhan Baytar Ömer Şahin Sabit Horoz Source Type: research

Superior incident photon-to-current conversion efficiency of Mo-doped activated carbon supported CdS-sensitized solar cells
This study presents a new strategy to increase the solar cell efficiency of semiconductor-based solar cell structures using biowaste-based AC supported CdS semiconductor materials.PMID:36239891 | DOI:10.1007/s11356-022-23552-1 (Source: Cell Research)
Source: Cell Research - October 14, 2022 Category: Cytology Authors: Ebru Batur Sinan Kutluay Orhan Baytar Ömer Şahin Sabit Horoz Source Type: research

Superior incident photon-to-current conversion efficiency of Mo-doped activated carbon supported CdS-sensitized solar cells
This study presents a new strategy to increase the solar cell efficiency of semiconductor-based solar cell structures using biowaste-based AC supported CdS semiconductor materials.PMID:36239891 | DOI:10.1007/s11356-022-23552-1 (Source: Environmental Science and Pollution Research International)
Source: Environmental Science and Pollution Research International - October 14, 2022 Category: Environmental Health Authors: Ebru Batur Sinan Kutluay Orhan Baytar Ömer Şahin Sabit Horoz Source Type: research

Studying the Anticancer Effects of Thymoquinone on Breast Cancer Cells through Natural Killer Cell Activity
Conclusion. Thymoquinone promotes the cytotoxic activity of NK cells against breast cancer MCF-7 cells.PMID:36199754 | PMC:PMC9527111 | DOI:10.1155/2022/9218640 (Source: Biomed Res)
Source: Biomed Res - October 6, 2022 Category: Research Authors: Huda F Alshaibi Nouf A Aldarmahi Nuha A Alkhattabi Hadeil M Alsufiani Nesrin I Tarbiah Source Type: research

Studying the Anticancer Effects of Thymoquinone on Breast Cancer Cells through Natural Killer Cell Activity
Conclusion. Thymoquinone promotes the cytotoxic activity of NK cells against breast cancer MCF-7 cells.PMID:36199754 | PMC:PMC9527111 | DOI:10.1155/2022/9218640 (Source: Cell Research)
Source: Cell Research - October 6, 2022 Category: Cytology Authors: Huda F Alshaibi Nouf A Aldarmahi Nuha A Alkhattabi Hadeil M Alsufiani Nesrin I Tarbiah Source Type: research

Molecules, Vol. 27, Pages 6590: Natural Phytocompounds from Common Indian Spices for Identification of Three Potential Inhibitors of Breast Cancer: A Molecular Modelling Approach
haman Breast cancer is the second most common cancer-related cause of death for women throughout the globe. In spite of some effective measures, the main concerns with traditional anti-cancer chemotherapy are its low bioavailability, physical side effects, acquired resistance of cancer cells and non-specific targeting. Now researchers have taken the initiative to establish natural product-based therapy methods and to identify viable hits for future lead optimization in the development of breast cancer medication. Our study aims to identify the potent phytocompounds from five very popular Indian spices (Zingiber officin...
Source: Molecules - October 5, 2022 Category: Chemistry Authors: Samik Hazra Anindya Sundar Ray Chowdhury Habibur Rahaman Tags: Article Source Type: research

Thymoquinone counteracts oxidative and inflammatory machinery in carrageenan-induced murine paw edema model
Environ Sci Pollut Res Int. 2022 Oct 3. doi: 10.1007/s11356-022-23343-8. Online ahead of print.ABSTRACTThymoquinone (TQ) is an active constituent in Nigella sativa (black cumin) and is extensively reported for its distinguished antioxidant and anti-inflammatory bioactivities. Despite the local protective response of acute inflammation, it contributes to the development of various disease conditions such as cell death, organ damage, or carcinogenesis. Hence, in this study, the effects of orally administered TQ (50 mg/kg and 100 mg/kg) for 14 days against edema development, oxidative stress, and inflammation were investigate...
Source: Environmental Science and Pollution Research International - October 2, 2022 Category: Environmental Health Authors: Hayfa Hussin Ali Hijazy Naief Dahran Hussam A Althagafi Fahad Alharthi Ola A Habotta Atif Abdulwahab A Oyouni Mohammad Algahtani Abdulrahman Theyab Osama Al-Amer Maha S Lokman Khalaf F Alsharif Ashraf Albrakati Hatem K Amin Shauq Mumtaz Dawood Rami B Kass Source Type: research

Molecules, Vol. 27, Pages 6403: Spices Volatilomic Fingerprinting & mdash;A Comprehensive Approach to Explore Its Authentication and Bioactive Properties
This study aimed to establish the volatilomic fingerprint of six of the most consumed spices all over the world (saffron (Crocus sativus L.), cinnamon (Cinnamomum verum), cumin (Cuminum cyminum L.), black pepper, (Piper nigrum L.), sweet paprika (Capsicum annuum L.), and curry (a mix of different herbs and spices)). Based on headspace solid phase microextraction (HS-SPME) followed by gas chromatography-mass spectrometry (GC-MS) analysis, this is a powerful strategy to explore and establish the spice’s volatile pattern and unravel the potential health benefits related to the most important VOMs identified in e...
Source: Molecules - September 28, 2022 Category: Chemistry Authors: Sergio Izcara Rosa Perestrelo Sonia Morante-Zarcero Isabel Sierra Jos é S. Câmara Tags: Article Source Type: research

Molecules, Vol. 27, Pages 6342: Effect of Black Cumin Cake Addition on the Chemical Composition, Glycemic Index, Antioxidant Activity, and Cooking Quality of Durum Wheat Pasta
ner-Szkudlarz Pasta is a good carrier for plant enrichment substances due to its popularity among consumers. The purpose of the study was to investigate the functional potential and optimize the recipe of pasta made from durum semolina with the addition of black cumin cake at the level of 5, 10, 15, 20, and 25%. The use of black cumin cake resulted in a statistically significant (p ≤ 0.05) increase in the content of protein, fat, ash, and fiber, including both the insoluble and soluble fractions. A reduction in the digestible carbohydrate content, in vitro starch hydrolysis index (HI), was observed. Pasta wi...
Source: Molecules - September 26, 2022 Category: Chemistry Authors: Ada Kraw ęcka Aldona Sobota Eva Ivani šová Ľuboš Harangozo Veronika Valkov á Ewelina Zieli ńska Agata Blicharz-Kania Beata Zdybel Sylwia Mildner-Szkudlarz Tags: Article Source Type: research

Fumigant and contact toxicities of individual and additive combinations of biorational-essential oils for control of rice weevil ( < em > Sitophilus oryzae) < /em >
Nat Prod Res. 2022 Sep 21:1-5. doi: 10.1080/14786419.2022.2125967. Online ahead of print.ABSTRACTFumigant and contact activity of individual and combination of EOs (cumin seed and black pepper oil) were conducted against rice weevil (Sitophilus oryzae). Cumin seed and black pepper oil individually exhibited 100% insecticidal activity (Contact and Fumigant) against S. oryzae at 24 and 168 h of exposure in the absence and presence of food, respectively. Overall, differential insect mortality rates were observed with individual EOs; however, cumin seed EO showed higher insecticidal activity in both fumigant and contact bioass...
Source: Natural Product Research - September 21, 2022 Category: Biochemistry Authors: Archana V Remesh C S Vivek Babu Source Type: research

Response to Direct Selection against Drought Stress in Black Cumin ( < em > Nigella sativa < /em > L.)
Evid Based Complement Alternat Med. 2022 Sep 5;2022:6888187. doi: 10.1155/2022/6888187. eCollection 2022.ABSTRACTCentral Anatolia is prone to drought with low precipitation and high evapotranspiration which influence the growth of a several crops. The selection and cultivation of drought-tolerant crops that can survive and maintain under poor climatic conditions are very important. Black cumin (Nigella sativa L. Umbelliferae) is famous for aromatic, medicinal, and therapeutic uses in the Mediterranean region and elsewhere. Drought stress most often delays or reduces seed germination ending up in irregular and poor crop gro...
Source: Evidence-based Complementary and Alternative Medicine - September 15, 2022 Category: Complementary Medicine Authors: Fatma Kayacetin Source Type: research

Annual phytochemical variations and antioxidant activity within the aerial parts of Lavandula angustifolia, an evergreen medicinal plant
Chem Biodivers. 2022 Sep 13. doi: 10.1002/cbdv.202200536. Online ahead of print.ABSTRACTAcknowledging the importance of medicinal compounds, flavonoids, and phenolic acids in plants and human health; understanding the best time to harvest the plant to get the most biological activity that can be therapeutic, and predicting and controlling the quality of medicinal plants are very useful. The rich chemical composition of medicinal lavender, as well as its antioxidant activity, has led to its wide application in the pharmaceutical, cosmetic, and food industries. In the current research, seasonal differences in phenolic conten...
Source: Chemistry and Biodiversity - September 13, 2022 Category: Biochemistry Authors: Sharareh Najafian Mahmoud Afshara Mohsen Radi Source Type: research

Effects of dietary supplementation of cumin ( < em > Cuminum cyminum < /em > L.) essential oil on expression of genes related to antioxidant, apoptosis, detoxification, and heat shock mechanism in heat-stressed broiler chickens
This study was carried out to evaluate the impact of cumin essential oil (CEO) supplementation on levels of certain gene expression related to antioxidant, apoptotic, detoxific, and heat shock mechanisms in the breast meat and ileum of heat-stressed broilers. The study was conducted on a 2 × 6 factorial design (heat stress + feed additive) on 600 day-old male broiler chicks for a period of 42 days. From day 7 to 42, although broilers in heat stress groups (HT) were exposed to constant chronic heat stress (36 °C), others were housed at thermoneutral ambient temperature (TN). The chicks in both conditions were fed with 6 e...
Source: Animal Biotechnology - September 2, 2022 Category: Biotechnology Authors: Emre Yilmaz Mehmet Gul Source Type: research

Effects of dietary supplementation of cumin ( < em > Cuminum cyminum < /em > L.) essential oil on expression of genes related to antioxidant, apoptosis, detoxification, and heat shock mechanism in heat-stressed broiler chickens
This study was carried out to evaluate the impact of cumin essential oil (CEO) supplementation on levels of certain gene expression related to antioxidant, apoptotic, detoxific, and heat shock mechanisms in the breast meat and ileum of heat-stressed broilers. The study was conducted on a 2 × 6 factorial design (heat stress + feed additive) on 600 day-old male broiler chicks for a period of 42 days. From day 7 to 42, although broilers in heat stress groups (HT) were exposed to constant chronic heat stress (36 °C), others were housed at thermoneutral ambient temperature (TN). The chicks in both conditions were fed with 6 e...
Source: Animal Biotechnology - September 2, 2022 Category: Biotechnology Authors: Emre Yilmaz Mehmet Gul Source Type: research