Exploring the potential of black cumin derived nanovesicles for miRNA drug delivery
Eur J Pharm Biopharm. 2024 Apr 4:114275. doi: 10.1016/j.ejpb.2024.114275. Online ahead of print.ABSTRACTLiposomes is a non-viral vector drug delivery system. Nevertheless, the existing commercial liposomes are quite expensive and not always affordable, particularly in developing countries. To address this challenge, plant-derived nanoparticles offer a cost-effective alternative while maintaining similar drug delivery capabilities. Hence, this study aimed to explore the potential of nanovesicles derived from black cumin (Nigella sativa) as a miRNA delivery system. Gradient sucrose-centrifugation was utilized to separate the...
Source: European Journal of Pharmaceutics and Biopharmaceutics - April 6, 2024 Category: Drugs & Pharmacology Authors: Adelina Khristiani Rahayu Azzania Fibriani Marselina Irasonia Tan Source Type: research
Exploring the potential of black cumin derived nanovesicles for miRNA drug delivery
Eur J Pharm Biopharm. 2024 Apr 4:114275. doi: 10.1016/j.ejpb.2024.114275. Online ahead of print.ABSTRACTLiposomes is a non-viral vector drug delivery system. Nevertheless, the existing commercial liposomes are quite expensive and not always affordable, particularly in developing countries. To address this challenge, plant-derived nanoparticles offer a cost-effective alternative while maintaining similar drug delivery capabilities. Hence, this study aimed to explore the potential of nanovesicles derived from black cumin (Nigella sativa) as a miRNA delivery system. Gradient sucrose-centrifugation was utilized to separate the...
Source: Cancer Control - April 6, 2024 Category: Cancer & Oncology Authors: Adelina Khristiani Rahayu Azzania Fibriani Marselina Irasonia Tan Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research
