Efficacy of hydroxyapatite and fibrin sealant as carriers for bone morphogenetic protein-2 in maxillary sinus floor augmentation: a retrospective study
The aim of this retrospective study was to assess the efficacy of recombinant human bone morphogenetic protein-2 (rhBMP-2) with hydroxyapatite (HA) granules and fibrin sealant (FS) in maxillary sinus floor augmentation (MSFA), with a focus on the volume change. Fifty-two of 137 patients who underwent MSFA with rhBMP-2/HA grafting between June 2016 and December 2022 met the study inclusion criteria; 25 had received rhBMP-2/HA without FS and 27 had received rhBMP-2/HA with FS. Computed tomography (CT) images were obtained preoperatively, immediately following the operation, and at 6 months postoperative. (Source: Internation...
Source: International Journal of Oral and Maxillofacial Surgery - April 22, 2024 Category: ENT & OMF Authors: J.W. Nam Tags: Clinical Paper Source Type: research
Using an artificial intelligence software improves emergency medicine physician intracranial haemorrhage detection to radiologist levels
Conclusion
The Caire ICH software significantly improved the accuracy and sensitivity of detecting an ICH by the EP to a level comparable to general radiologists. Further prospective research with larger numbers will be needed to understand the impact of Caire ICH on ED logistics and patient outcomes. (Source: Emergency Medicine Journal)
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: Warman, P., Warman, A., Warman, R., Degnan, A., Blickman, J., Smith, D., McHale, P., Coburn, Z., McCormick, S., Chowdhary, V., Dash, D., Sangal, R., Vadhan, J., Bueso, T., Windisch, T., Neves, G. Tags: Original research Source Type: research
Successful curative treatment for a ruptured pancreatic acinar cell carcinoma by radical resection following modified FOLFIRINOX: a case report and literature review
AbstractPancreatic acinar cell carcinoma (PACC) is a rare pancreatic tumor type, and ruptured pancreatic tumors are rarer. Computed tomography (CT) in a 48-year-old man incidentally revealed a raptured pancreatic tail tumor. The patient was treated conservatively because he was asymptomatic, and his general condition was stable. After a detailed examination, the pancreatic tumor was diagnosed as raptured PACC. Considering the potential infiltration of tumor cells into the hematoma within the omental sac, our decision is to initiate chemotherapy as the primary course of action. A liquid biopsy was performed, and comprehensi...
Source: International Cancer Conference Journal - April 22, 2024 Category: Cancer & Oncology Source Type: research
Rationale and design of the PACIFIC-PRESERVED (PhenomApping, ClassIFication and Innovation for Cardiac dysfunction in patients with heart failure and PRESERVED left ventricular ejection fraction) study
CONCLUSIONS: PACIFIC-PRESERVED is a prospective multicentre phenomapping study, using novel analytical techniques, which will provide a unique data resource to better define HFpEF and identify new clinically meaningful subgroups of patients.PMID:38644067 | DOI:10.1016/j.acvd.2024.02.011 (Source: Archives of Cardiovascular Diseases)
Source: Archives of Cardiovascular Diseases - April 21, 2024 Category: Cardiology Authors: Jean-S ébastien Hulot Philip Janiak Philippe Boutinaud Pierre Boutouyrie Fr édérique Chézalviel-Guilbert Jean-Joseph Christophe Ariel Cohen Thibaud Damy Juliette Djadi-Prat H üseyin Firat Pierre-Yves Herv é Richard Isnard Guillaume Jondeau Elie Mous Source Type: research
Pericarotid Adipose Tissue is Associated with Circulatory Markers of Inflammation and Carotid Atherosclerosis
Angiology. 2024 Apr 21:33197241248776. doi: 10.1177/00033197241248776. Online ahead of print.ABSTRACTPerivascular adipose tissue plays roles in vascular inflammation and atherosclerosis. The present study aimed to evaluate the association between pericarotid fat density (PFD) and circulatory inflammatory indicators, internal carotid artery (ICA) stenosis, and vulnerable carotid plaques. We retrospectively screened 498 consecutive patients who underwent both computed tomography angiography of the neck between January 2017 and December 2020. The PFD, ICA stenosis, and vulnerable carotid plaques were analyzed using establishe...
Source: Atherosclerosis - April 21, 2024 Category: Cardiology Authors: Lingqun Mao Linkao Chen Man Qu Xinwei He Source Type: research
Safety and effectiveness of anticoagulation in the management of acute stroke and transient ischemic attack due to intracranial and extracranial non-occlusive thrombus
CONCLUSION: Anticoagulant treatment is safe and effective in symptomatic patients with intracranial or extracranial artery nonocclusive thrombus, regardless of the anticoagulant type, thrombus location and size.PMID:38643651 | DOI:10.1016/j.jocn.2024.04.012 (Source: Atherosclerosis)
Source: Atherosclerosis - April 21, 2024 Category: Cardiology Authors: Aysenur Onalan Erdem Gurkas Cetin Kursad Akpinar Ozlem Aykac Zehra Uysal Kocabas Hasan Dogan Musa Temel Atilla Ozcan Ozdemir Source Type: research
Radiographic Progression at Castration-Resistant Prostate Cancer Diagnosis: A Prognostic Indicator of Metastatic Hormone-Sensitive Prostate Cancer
CONCLUSION: Radiographic progression at the point of CRPC diagnosis independently predicts a shorter OS post-CRPC in patients with mHSPC. Therefore, assessing radiographic changes at the time of CRPC diagnosis could be instrumental in managing CRPC in patients with mHSPC.PMID:38643665 | DOI:10.1016/j.clgc.2024.102075 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - April 21, 2024 Category: Cancer & Oncology Authors: Kojiro Tashiro Shoji Kimura Shunsuke Tsuzuki Fumihiko Urabe Wataru Fukuokaya Keiichiro Mori Koichi Aikawa Masaya Murakami Hiroshi Sasaki Kenta Miki Jun Miki Tatsuya Shimomura Hiroki Yamada Kenichi Hata Hideomi Nishikawa Hirokazu Abe Ken Watanabe Takahiro Source Type: research
Redefining Clinical Hyperprogression: The Incidence, Clinical Implications, and Risk Factors of Hyperprogression in Non-Small Cell Lung Cancer Treated with Immunotherapy
CONCLUSIONS: The incidence and risk factors of HPD varied with different definitions, but mHPD identified more cases with poor outcomes. This comprehensive approach may enhance the identification of at-risk patients and lead to a better understanding of HPD in lung cancer during immunotherapy.PMID:38644088 | DOI:10.1016/j.cllc.2024.03.001 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 21, 2024 Category: Cancer & Oncology Authors: Trie Arni Djunadi Youjin Oh Jeeyeon Lee Jisang Yu Liam Il-Young Chung Yeunho Lee Leeseul Kim Timothy Hong Soowon Lee Zunairah Shah Joo Hee Park Sung Mi Yoon Young Kwang Chae Source Type: research
A case of insulinoma misidentified as schizophrenia due to its manifestation in neuropsychiatric symptoms
AbstractInsulinomas can present with neuroglycopenic symptoms suggesting neuropsychiatric disorders, delaying diagnosis and treatment. We recently treated a 65-year-old woman with insulinoma who was misdiagnosed at her nearby psychiatric clinic as having schizophrenia because of personality changes and memory impairment; she was treated with brexpiprazole, which was discontinued due to persistence of the symptoms. Despite her relatively low casual plasma glucose (70 mg/dL), the physician at the psychiatric clinic did not investigate the possibility of hypoglycemia, partly because her HbA1c level (5.2%) was within normal ...
Source: Diabetology International - April 21, 2024 Category: Endocrinology Source Type: research
A novel MRI-based Cervical-Endplate Bone Quality score independently predicts cage subsidence after Anterior Cervical Discectomy and Fusion
ConclusionsHigher C-EBQ scores were significantly associated with postoperative cage subsidence after ACDF. There was a significant negative correlation between C-EBQ and endplate HU values. The C-EBQ score may be a promising tool for assessing preoperative bone quality and postoperative cage subsidence and is superior to the C-VBQ. (Source: European Spine Journal)
Source: European Spine Journal - April 21, 2024 Category: Orthopaedics Source Type: research
Plasma cell myeloma in a 9 ‐year‐old male: Case report and literature review
Key Clinical MessagePlasma cell myeloma is a rare entity in the pediatric population. The peak incidence is in the seventh decade, with less than 2% of cases occurring in patients under the age of 40. It is worth noting that any destructive bony lesion in a child should be investigated.AbstractPlasma cell myeloma (multiple myeloma) is the most common form of plasma cell neoplasm. It is a rare entity in young patients. The peak incidence is in the seventh decade, with less than 2% of cases occurring in patients under the age of 40. A male patient aged 9 years old with a progressive pain in lower back for about 1 month,...
Source: Clinical Case Reports - April 20, 2024 Category: General Medicine Authors: Kato Ronald,
Ambaru Jacinta,
Ssebagala Umaru Tags: CASE REPORT Source Type: research
Optimizing Clinical Outcomes for Bronchoscopic Lung Volume Reduction with Zephyr ® Valves
Respir Med. 2024 Apr 18:107639. doi: 10.1016/j.rmed.2024.107639. Online ahead of print.ABSTRACTBronchoscopic lung volume reduction treatment with Zephyr one-way valves is an effective guideline-based treatment option for patients with severe emphysema and hyperinflation. However, in some cases the treatment response is less than anticipated or there might be a loss of initial treatment effect. Reasons for the lack of response can include incorrect assessment of collateral ventilation, improper valve placement, or patient related factors. Loss of initial benefit can be due to granulation tissue formation and subsequent valv...
Source: Respiratory Care - April 20, 2024 Category: Respiratory Medicine Authors: T David Koster Pallav L Shah Arschang Valipour Gerard J Criner Felix J F Herth Richard Sue Douglas K Hogarth Ralitza T Martin Amit K Mahajan Raed Alalawi Lisa Kopas Avi Cohen Douglas E Wood Jonathan Kurman Narinder S Shargill Mark Dransfield Dirk-Jan Sleb Source Type: research
Prevalence and prognostic meaning of interstitial lung abnormalities in remote CT scans of patients with interstitial lung disease treated with antifibrotic therapy
CONCLUSIONS: Fibrotic ILAs are frequent in remote scans of patients with clinically relevant ILD, long before they require antifibrotics. Findings of traction bronchiectasis and honeycombing in the earliest scans, even in asymptomatic patients, are related to mortality and progression later on.PMID:38642956 | DOI:10.1016/j.rxeng.2023.03.006 (Source: Radiologia)
Source: Radiologia - April 20, 2024 Category: Radiology Authors: M M Garc ía Mullor J J Arenas-Jim énez A Ure ña Vacas I Gay á García-Manso J L P érez Pérez N Serra Serra R Garc ía Sevila Source Type: research
Usefulness of thoracic ultrasound in the assessment of removal of indwelling pleural catheter in patients with malignant pleural effusion
CONCLUSIONS: Thoracic ultrasound performed by an expert pulmonologist is a valid and simple tool to determine spontaneous pleurodesis and remove a non-functioning IPC, which would make it possible to avoid chest CT in those cases in which lung reexpansion is observed with ultrasonography.PMID:38642957 | DOI:10.1016/j.rxeng.2023.04.008 (Source: Radiologia)
Source: Radiologia - April 20, 2024 Category: Radiology Authors: M Iglesias Heras E Ju árez Moreno J Ortiz de Saracho Bobo J Casc ón Hernández J M Fern ández García-Hierro E Yag üe Zapatero R Cordovilla P érez Source Type: research
Utility of artificial intelligence for detection of pneumothorax on chest radiopgraphs done after transthoracic percutaneous transthoracic biopsy guided by computed tomography
CONCLUSIONS: The software has detected 100% of cases of pneumothorax in the postbiopsy chest radiographs. A potential use of this software could be as a prioritisation tool, allowing radiologists not to read immediately (or even not to read) chest radiographs classified as non-pathological by the software, with the confidence that there are no pathological cases.PMID:38642960 | DOI:10.1016/j.rxeng.2023.07.006 (Source: Radiologia)
Source: Radiologia - April 20, 2024 Category: Radiology Authors: D Ferrando Blanco Ó Persiva Morenza L B Cabanzo Campos A L S ánchez Martínez D Varona Porres L A Del Carpio Bellido Vargas J Andreu Soriano Source Type: research
