Long-Term Outcomes of LAA Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT Registry
Conditions: Atrial Fibrillation; Ischemic Stroke, Acute Interventions: Other: Left Atrial Appendage Occlusion Sponsors: Kansas City Heart Rhythm Research Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 10, 2023 Category: Research Source Type: clinical trials

A Combined Biomarker Model for Risk Stratification of Indeterminate Pulmonary Nodules
Conditions: Pulmonary Nodule Interventions: Procedure: Blood collection; Procedure: Chest Computed Tomography Sponsors: Vanderbilt-Ingram Cancer Center; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 9, 2023 Category: Research Source Type: clinical trials

Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study
Conditions: Microvascular Angina Interventions: Diagnostic Test: Coronary microvascular disease testing during coronary angiography; Diagnostic Test: Cardiac magnetic resonance scan including exercise; Diagnostic Test: Additional analysis of already acquired CT scan Sponsors: University of Leicester Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 6, 2023 Category: Research Source Type: clinical trials

Radiotherapy Exposed Lung Injury: Effect on Functioning - Cohort
Conditions: Breast Neoplasms; Radiation Pneumonia; Radiation Pneumonitis; Radiation Induced Fibrosis Interventions: Radiation: Radiation therapy protocol for Breast cancer; Diagnostic Test: Spirography and assessment of pulmonary diffusion capacity; Diagnostic Test: Cardiopulmonary stress test; Diagnostic Test: Computed tomography of the chest organs; Diagnostic Test: SF-36 Quality of Life Questionnaire; Diagnostic Test: Demographic and anthropometric measures; Other: Indicators characterizing the severity of the underlying disease Sponsors: Meshalkin Research Institute of Pathology of Circulation Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 5, 2023 Category: Research Source Type: clinical trials

Biomarkers to Detect Endocrine Therapy Resistance
Conditions: Metastatic Cancer; Breast Cancer; Lobular Breast Carcinoma Interventions: Drug: 18F-fluorofuranylnorprogesterone; Device: Liquid Biopsy; Device: Positron Emission Tomography/Computed Tomography Sponsors: University of Wisconsin, Madison Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 5, 2023 Category: Research Source Type: clinical trials

COMPASS: deCOMPressing stomA and two-Stage elective resection vs. emergency reSection in patients with left-sided obstructive colon cancer
DiscussionThe findings derived from this trial possess the potential to reshape the current clinical approach of emergency resection for obstructive left-sided colon cancer by favoring the bridge-to-surgery practice, provided that a reduction in morbidity can be achieved without compromising the oncological long-term outcome.Trial registrationGerman Clinical Trials Register (DRKS) under the identifier DRKS00031827. Registered on May 15, 2023.Protocol: 28.04.2023, protocol version 2.0F. (Source: Trials)
Source: Trials - October 5, 2023 Category: Research Source Type: clinical trials

Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial
Conditions: Prostate Adenocarcinoma; Stage II Prostate Cancer AJCC v8; Stage IIIA Prostate Cancer AJCC v8; Stage IIIB Prostate Cancer AJCC v8 Interventions: Drug: Apalutamide; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Other: Gallium Ga 68 Gozetotide; Radiation: MRI-guided Stereotactic Body Radiation Therapy; Procedure: Multiparametric Magnetic Resonance Imaging; Procedure: Positron Emission Tomography; Other: Questionnaire Administration Sponsors: Jonsson Comprehensive Cancer Center; Janssen Scientific Affairs, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 4, 2023 Category: Research Source Type: clinical trials

Total Small Bowel Length Measurement Using Computed Tomography and Magnetic Resonance Imaging in Obese Patients
Conditions: Obesity; Bariatric Surgery Candidate Interventions: Diagnostic Test: Measurement of the total small bowel length using CT scan and MRI with 3D reconstruction and AI tool Sponsors: University of Roma La Sapienza; University of Padova; Federico II University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 4, 2023 Category: Research Source Type: clinical trials

A Study Using a New Drug, Nivolumab, in Combination With Chemotherapy Drugs to Treat a Type of Cancer Called Nasopharyngeal Carcinoma (NPC)
Conditions: Stage II Nasopharyngeal Carcinoma AJCC v8; Stage III Nasopharyngeal Carcinoma AJCC v8; Stage IV Nasopharyngeal Carcinoma AJCC v8 Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Chest Radiography; Drug: Cisplatin; Procedure: Computed Tomography; Procedure: Echocardiography; Other: Electronic Health Record Review; Other: Fluciclovine F18; Drug: Gemcitabine; Procedure: Magnetic Resonance Imaging; Procedure: Multigated Acquisition Scan; Biological: Nivolumab; Procedure: Positron Emission Tomography; Other: Quality-of-Life Assessment; Other: Questionnaire Administration; Radiation: Ra...
Source: ClinicalTrials.gov - October 3, 2023 Category: Research Source Type: clinical trials

Correction: Prospective randomized study on the efficacy of three-dimensional reconstructions of bronchovascular structures on preoperative chest CT scan in patients who are candidates for pulmonary segmentectomy surgery: the PATCHES (Prospective rAndomized sTudy efficaCy of tHree-dimensional rEconstructions Segmentecomy) study protocol
(Source: Trials)
Source: Trials - October 3, 2023 Category: Research Source Type: clinical trials

Pericapsular Nerve Group Block: An Imaging Study for Determination of the Spread of the Injectate Using 3-D CT Scan
Conditions: Post Operative Pain; Mechanisms of Analgesia Interventions: Procedure: Pericapsular nerve group block; Drug: local anesthetic mixed with contrast agent Sponsors: Philippe Gauthier Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 2, 2023 Category: Research Source Type: clinical trials

Improving Patient Understanding in Preoperative Informed Consent Process of Trauma Patients Using a Mixed Reality Viewer
Conditions: Distal Radius Fractures; Ankle Fractures; Proximal Humeral Fracture Interventions: Device: Mixed Reality Viewer; Device: X-ray or CT scan Sponsors: LMU Klinikum Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 2, 2023 Category: Research Source Type: clinical trials

Multimodal Computed Tomography of Aneurysmal Subarachnoid Hemorrhage
Conditions: Aneurysmal Subarachnoid Hemorrhage Interventions: Device: Multimodal CT Sponsors: Xiaolin Chen, MD Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 29, 2023 Category: Research Source Type: clinical trials

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced, Unresectable Intrahepatic Cholangiocarcinoma
Conditions: Locally Advanced Intrahepatic Cholangiocarcinoma; Oligometastatic Intrahepatic Cholangiocarcinoma; Stage III Intrahepatic Cholangiocarcinoma AJCC v8; Stage IV Intrahepatic Cholangiocarcinoma AJCC v8; Unresectable Intrahepatic Cholangiocarcinoma Interventions: Procedure: Angiography; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Biological: Durvalumab; Procedure: Magnetic Resonance Imaging; Procedure: Positron Emission Tomography; Biological: Tremelimumab; Procedure: Yttrium-90 Microsphere Radioembolization Sponsors: Mayo Clinic; National Cancer Institute (NCI) Not yet rec...
Source: ClinicalTrials.gov - September 28, 2023 Category: Research Source Type: clinical trials

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma
Conditions: Unresectable Clinical Stage III Merkel Cell Carcinoma AJCC v8; Clinical Stage IV Merkel Cell Carcinoma AJCC v8; Merkel Cell Carcinoma Interventions: Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Procedure: Magnetic Resonance Imaging; Biological: Retifanlimab; Drug: Tuparstobart; Drug: Verzistobart Sponsors: University of Washington; Incyte Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 28, 2023 Category: Research Source Type: clinical trials