Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome
Conditions: Ischemic Heart Disease; Non STEMI; Angina Pectoris, Unstable Interventions: Procedure: CCTA; Procedure: Conventional ICA; Other: Team-based interventional triage Sponsors: Herlev and Gentofte Hospital; Rigshospitalet, Denmark; Zealand University Hospital; North Zealand Hospital, Denmark; Amager Hospital; Bispebjerg Hospital; Hvidovre University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 26, 2023 Category: Research Source Type: clinical trials

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer
Conditions: Metastatic Colorectal Adenocarcinoma; Refractory Colorectal Adenocarcinoma; Stage IV Colorectal Cancer AJCC v8 Interventions: Drug: BET Bromodomain Inhibitor ZEN-3694; Procedure: Biopsy; Procedure: Biospecimen Collection; Biological: Cetuximab; Procedure: Computed Tomography; Drug: Encorafenib; Procedure: Magnetic Resonance Imaging Sponsors: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 26, 2023 Category: Research Source Type: clinical trials

Chemotherapy Combined With Immunotherapy vs Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
Conditions: Advanced Lung Non-Small Cell Carcinoma; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8 Interventions: Drug: Carboplatin; Procedure: Computed Tomography; Procedure: Magnetic Resonance Imaging; Drug: Nab-paclitaxel; Drug: Paclitaxel; Biological: Pembrolizumab; Drug: Pemetrexed; Procedure: Positron Emission Tomography; Other: Quality-of-Life Assessment; Other: Questionnaire Administration Sponsors: National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 24, 2023 Category: Research Source Type: clinical trials

Autologous T Cells Lentivirally Transduced to Express L1CAM-Specific Chimeric Antigen Receptors in Treating Patients With Locally Advanced and Unresectable or Metastatic Small Cell Neuroendocrine Prostate Cancer
Conditions: Prostate Carcinoma; Prostate Small Cell Neuroendocrine Carcinoma; Stage III Prostate Cancer AJCC v8; Stage IV Prostate Cancer AJCC v8 Interventions: Drug: Bendamustine; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Scan; Procedure: Bridge Therapy; Procedure: Computed Tomography; Drug: Cyclophosphamide; Procedure: Echocardiography; Drug: Fludarabine; Procedure: Leukapheresis; Procedure: Multigated Acquisition Scan; Biological: T-cell Receptor-engineered T-cells; Procedure: X-Ray Imaging Sponsors: Fred Hutchinson Cancer Center; Bristol-Myers Squibb Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2023 Category: Research Source Type: clinical trials

The tooth movement efficiency of different orthodontic thermoplastics for clear aligners: study protocol for a randomized controlled clinical trial
DiscussionThe results from this trial will serve as evidence for orthodontists and manufacturers and clarify whether the difference in orthodontic thermoplastics significantly impacts the efficiency of OTM.Trial registration numberChiCTR2300070980. Registered on 27 April 2023.https://www.chictr.org.cn/showproj.html?proj=186253 (Source: Trials)
Source: Trials - October 23, 2023 Category: Research Source Type: clinical trials

Letting Children Listen to Music During Computed Tomography
Conditions: Fear; Computed Tomography Interventions: Other: Music Sponsors: G ümüşhane Universıty Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer
Conditions: Head and Neck Squamous Cell Carcinoma; Hypopharyngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma; Oral Cavity Squamous Cell Carcinoma; Oropharyngeal Squamous Cell Carcinoma; Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage III Hypopharyngeal Carcinoma AJCC v8; Stage III Laryngeal Cancer AJCC v8; Stage III Lip and Oral Cavity Cancer AJCC v8; Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage IV Hypopharyngeal Carcinoma AJCC v8; Stage IV Laryngeal Cancer AJCC v8; Stage IV Lip and Or...
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials

Vascular Inflammation ReDuction and Perivascular Fat Imaging by Computed Tomography
Conditions: Coronary Artery Disease; Atheroscleroses, Coronary; Vascular Inflammation Interventions: Device: CaRi-Heart device Sponsors: Hippocration General Hospital; Biomedical Research Foundation, Academy of Athens Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials

Protocol Based Selective Imaging Versus Routine Computed Tomography or Ultrasound in Suspected Appendicitis
Conditions: Appendicitis Interventions: Diagnostic Test: Abdominal imaging; Other: Score based selective abdominal imaging; Other: Score based selective observation combined with selective abdominal imaging Sponsors: Helsinki University Central Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 13, 2023 Category: Research Source Type: clinical trials

Olfactory Cleft Stenosis and Obstruction on Paranasal Sinus CT Scan in Pre Septo Rhinoplasty Patients Without Respiratory Mucosa Pathology : Normal Variants or Pathologic Findings ?
Conditions: Olfactory Impairment Sponsors: Central Hospital, Nancy, France Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 13, 2023 Category: Research Source Type: clinical trials

The Beneficial Value of PET/CT in the Follow-up of Stage III Non-small Cell Lung Cancer Patients
Conditions: Stage III Non-small Cell Lung Cancer Interventions: Diagnostic Test: 18F FDG PET/CT; Diagnostic Test: CT scan Sponsors: Radboud University Medical Center; Amsterdam UMC, location VUmc; The Netherlands Cancer Institute; Streekziekenhuis Koningin Beatrix; Canisius-Wilhelmina Hospital; Diakonessenhuis, Utrecht; Dijklander Ziekenhuis; Deventer Ziekenhuis; Elkerliek Hospital; Elisabeth-TweeSteden Ziekenhuis; Gelre Hospitals; Groene Hart Ziekenhuis; HagaZiekenhuis; Martini Hospital Groningen; Medisch Spectrum Twente; Noordwest Ziekenhuisgroep; OLVG; St. Antonius Hospital; Franciscus&Vlietland; Tjongerschans; Maasstad...
Source: ClinicalTrials.gov - October 13, 2023 Category: Research Source Type: clinical trials

Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma
Conditions: Clinical Stage I Esophageal Adenocarcinoma AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage II Esophageal Adenocarcinoma AJCC v8; Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 Interventions: Procedure: Biospecimen Collection; Procedure: Computed Tomography; Procedure: Endoscopic Ultrasound; Procedure: Esophagogastroduodenoscopy; Drug: Fluorouracil; Radiation: Hypofractionated Radiation Therapy; Drug: Leucovorin Calcium; Drug: Ox...
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials

Long-Term Outcomes of LAA Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT Registry
Conditions: Atrial Fibrillation; Ischemic Stroke, Acute Interventions: Other: Left Atrial Appendage Occlusion Sponsors: Kansas City Heart Rhythm Research Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 10, 2023 Category: Research Source Type: clinical trials

A Combined Biomarker Model for Risk Stratification of Indeterminate Pulmonary Nodules
Conditions: Pulmonary Nodule Interventions: Procedure: Blood collection; Procedure: Chest Computed Tomography Sponsors: Vanderbilt-Ingram Cancer Center; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 9, 2023 Category: Research Source Type: clinical trials

Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study
Conditions: Microvascular Angina Interventions: Diagnostic Test: Coronary microvascular disease testing during coronary angiography; Diagnostic Test: Cardiac magnetic resonance scan including exercise; Diagnostic Test: Additional analysis of already acquired CT scan Sponsors: University of Leicester Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 6, 2023 Category: Research Source Type: clinical trials