Crohn's Disease Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Association of Inflammatory Bowel Disease with Incident Immunoglobulin A Nephropathy
CONCLUSIONS: We demonstrated the potential association of inflammatory bowel disease with higher risk of developing IgA nephropathy in a general population.PMID:38600627 | DOI:10.2215/CJN.0000000000000457 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - April 11, 2024 Category: Urology & Nephrology Authors: Takashin Nakayama Hidehiro Kaneko Akira Okada Yuta Suzuki Katsuhito Fujiu Norifumi Takeda Hiroyuki Morita Norihiko Takeda Akira Fukui Takashi Yokoo Hideo Yasunaga Masaomi Nangaku Kaori Hayashi Source Type: research

Periodontitis increases the risk of gastrointestinal dysfunction: an update on the plausible pathogenic molecuar mechanisms
Crit Rev Microbiol. 2024 Apr 11:1-31. doi: 10.1080/1040841X.2024.2339260. Online ahead of print.ABSTRACTPeriodontitis is an immuno-inflammatory disease of the soft tissues surrounding the teeth. Periodontitis is linked to many communicable and non-communicable diseases such as diabetes, cardiovascular disease, rheumatoid arthritis, and cancers. The oral-systemic link between periodontal disease and systemic diseases is attributed to the spread of inflammation, microbial products and microbes to distant organ systems. Oral bacteria reach the gut via swallowed saliva, whereby they induce gut dysbiosis and gastrointestinal dy...
Source: Critical Reviews in Microbiology - April 11, 2024 Category: Microbiology Authors: Sayantan Mukherjee Aditi Chopra Shaswata Karmakar Subraya Giliyar Bhat Source Type: research

RuZn NPs with electroactivity and oxidase-like property for dual-mode anti-cancer drug monitoring
Talanta. 2024 Apr 8;274:126075. doi: 10.1016/j.talanta.2024.126075. Online ahead of print.ABSTRACT6-mercaptopurine (6-MP) as the effective anti-cancer drug was used for the treatment of Crohn's disease and acute lymphoblastic leukaemia, but the response to maintenance therapy was variable with individual differences. In order to control the dosage and decrease the side effects of 6-MP, a sensitive and stable assay was urgently needed for 6-MP monitoring. Herein, RuZn NPs with electrochemical oxidation property and oxidase-like activity was proposed for dual-mode 6-MP monitoring. Burr-like RuZn NPs were prepared and explore...
Source: Cancer Control - April 11, 2024 Category: Cancer & Oncology Authors: Zhao Jin Fang Peng Qiaodan Du Dan Liang Yuan Zhao Source Type: research

Phytotherapeutic recommendations in medical guidelines for the treatment of gastroenterological diseases - a systematic review
Z Gastroenterol. 2024 Apr 11. doi: 10.1055/a-2279-5045. Online ahead of print.ABSTRACTPhytotherapeutics are gaining influence in the treatment of gastroenterological diseases. Their popularity and growing evidence of efficacy contribute to their integration into medical guidelines. A systematic screening identified recommended phytotherapeutic approaches. Based on current scientific data, some recommendations for the use of phytotherapeutic agents are given. For irritable bowel syndrome the use of peppermint oil is "strongly recommended", especially for pain and flatulence. Other phytotherapeutics such as STW-5, Tibetan Pa...
Source: Zeitschrift fur Gastroenterologie - April 11, 2024 Category: Gastroenterology Authors: Sandra Utz Miriam Bittel Jost Langhorst Source Type: research

RuZn NPs with electroactivity and oxidase-like property for dual-mode anti-cancer drug monitoring
Talanta. 2024 Apr 8;274:126075. doi: 10.1016/j.talanta.2024.126075. Online ahead of print.ABSTRACT6-mercaptopurine (6-MP) as the effective anti-cancer drug was used for the treatment of Crohn's disease and acute lymphoblastic leukaemia, but the response to maintenance therapy was variable with individual differences. In order to control the dosage and decrease the side effects of 6-MP, a sensitive and stable assay was urgently needed for 6-MP monitoring. Herein, RuZn NPs with electrochemical oxidation property and oxidase-like activity was proposed for dual-mode 6-MP monitoring. Burr-like RuZn NPs were prepared and explore...
Source: Talanta - April 11, 2024 Category: Chemistry Authors: Zhao Jin Fang Peng Qiaodan Du Dan Liang Yuan Zhao Source Type: research

Case Report: Complicated Presentation Eventually Explained by Rare Syndrome
Pachydermoperiostosis (PDP), also known as Touraine-Solente-Golé syndrome or primary hypertrophic osteoarthropathy, is a rare syndrome that can be inherited as autosomal dominant, autosomal recessive, or sporadically. This progressive disease primarily affects males, who tend to have more severe features than females. PDP usually occurs during adolescence, often starting around puberty.1 The main clinical features are... (Source: The Rheumatologist)
Source: The Rheumatologist - April 10, 2024 Category: Rheumatology Authors: Geoffrey E. Thiele, MD, & Iris Reyhan, MD Tags: Conditions Other Rheumatic Conditions case report Crohn's disease Pachydermoperiostosis primary hypertrophic osteoarthropathy Touraine-Solente- Golé syndrome Source Type: research

Homotherapy for heteropathy: Interleukin-41 and its biological functions
Immunology. 2024 Apr 9. doi: 10.1111/imm.13791. Online ahead of print.ABSTRACTInterleukin-41 (IL-41) is a newly discovered cytokine, named Cometin, Subfatin, meteorin-like transcription (Metrnl), and so forth. It is widely expressed in animals and can exert its biological roles through autocrine and paracrine forms. It has functions such as anti-inflammatory, improving body metabolism, regulating immunity, regulating fat metabolism and participates in the process of autoimmune disease or inflammatory injury. It plays an important role in psoriasis, diabetes, Crohn's disease (CD), osteoarthritis, Kawasaki disease (KD), Grav...
Source: Immunology - April 10, 2024 Category: Allergy & Immunology Authors: Runfeng Shi Meixin He Yongzheng Peng Xu Xia Source Type: research

"Decoding inflammation: glycoprotein a repetition predominant, microRNA-142-3-p, and metastasis associated lung adenocarcinoma transcript 1: as novel inflammatory biomarkers of inflammatory bowel disease"
CONCLUSIONS: Dysregulation of GARP, MALAT1, and miR-142-3p likely contributes to inflammation in IBD by reducing TGF-β. MALAT1 is linked to smoking and age-related changes. These genes have potential as diagnostic markers or therapeutic targets for personalized IBD treatment.PMID:38598005 | DOI:10.1007/s11033-024-09475-9 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Mohammad Reza Lahimchi Mousa Mohammadnia-Afrouzi Rasoul Baharlou Dariush Haghmorad Seyed Hassan Abedi Delaram Arjmandi Masoomeh Hosseini Bahman Yousefi Source Type: research