Editorial Commentary: Bone Marrow Stimulation and  Losartan Augmentation of Shoulder Rotator Cuff Repair
Rotator cuff retear rates after repair have been variously reported as ranging from 5% to 40% for small to mediums tears and as high as 40% to 94% for large to massive tears. Thus strategies to enhance structural healing are relevant. In rabbits, combining oral losartan (which has antifibrotic effects by downregulating transforming growth factor- β1) and bone marrow stimulation (BMS) of the greater tuberosity, showed improved rotator cuff repair pull-out strength and highly organized tendon matrix in a chronic injury model, whereas BMS alone did not improve the mechanical properties. (Source: Arthroscopy - Journal of Arth...
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - November 18, 2023 Category: Surgery Authors: Noboru Taniguchi Tags: Editorial Commentary Source Type: research

Entelon150 < sup > ® < /sup > ( < em > Vitis vinifera < /em > Seed Extract) Attenuates Degenerative Changes in Intravascular Valve Prostheses in Rabbits
CONCLUSIONS: Entelon150® exhibited a significant effect, similar to other drugs, in reducing calcification and inflammation in the intravascular bovine pericardium.PMID:37973973 | DOI:10.4070/kcj.2023.0120 (Source: Korean Circulation Journal)
Source: Korean Circulation Journal - November 17, 2023 Category: Cardiology Authors: Jue Seong Lee JungHyeok Seo Sokho Kim Md Mahbubur Rahman Hong Ju Shin Source Type: research