Single nucleotide polymorphism (SNP) rs4291 of the angiotensin-converting enzyme (ACE) gene is associated with the response to losartan treatment in hypertensive patients
In conclusion, the presence of the T allele of the rs4291 variant was associated to controled blood pressure when losartan was used as an antihypertensive agent. These results show the importance of pharmacogenetic studies to detect genetic characteristics, enabling therapeutic individuality and reducing costs for the healthcare system.PMID:38551694 | DOI:10.1007/s11033-024-09437-1 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 29, 2024 Category: Molecular Biology Authors: L ívia da Cunha Agostini Wal éria de Paula Andr é Sacramento Melo Nayara Nascimento Toledo Silva Ana Cl áudia Faria Lopes Vanessa de Almeida Belo Wendel Coura-Vital Luiz Fernando de Medeiros Teixeira Ang élica Alves Lima Glenda Nicioli da Silva Source Type: research
Single nucleotide polymorphism (SNP) rs4291 of the angiotensin-converting enzyme (ACE) gene is associated with the response to losartan treatment in hypertensive patients
In conclusion, the presence of the T allele of the rs4291 variant was associated to controled blood pressure when losartan was used as an antihypertensive agent. These results show the importance of pharmacogenetic studies to detect genetic characteristics, enabling therapeutic individuality and reducing costs for the healthcare system.PMID:38551694 | DOI:10.1007/s11033-024-09437-1 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 29, 2024 Category: Molecular Biology Authors: L ívia da Cunha Agostini Wal éria de Paula Andr é Sacramento Melo Nayara Nascimento Toledo Silva Ana Cl áudia Faria Lopes Vanessa de Almeida Belo Wendel Coura-Vital Luiz Fernando de Medeiros Teixeira Ang élica Alves Lima Glenda Nicioli da Silva Source Type: research
Green synthesis of carbon nanotubes functionalized with iron nanoparticles and coffee husk biomass for efficient removal of losartan and diclofenac: Adsorption kinetics and ANN modeling studies
This study focused on the production of green functionalized carbon nanotubes (CNTs) and using them in the adsorption of the pharmaceuticals Losartan (LOS) and Diclofenac (DIC). The efficiency of the methodology was verified by characterization techniques. Elemental composition analysis indicated a significant increase in the iron content after the green functionalization, proving the effectiveness of the method. Thermogravimetric analysis showed similar thermal degradation profiles for pristine CNTs and functionalized CNTs, indicating better post-functionalization thermal stability. BET analysis revealed mesoporous charac...
Source: Environmental Research - March 23, 2024 Category: Environmental Health Authors: Heloisa P S Costa Emanuele D V Duarte Fl ávio V da Silva Meuris G C da Silva Melissa G A Vieira Source Type: research
Green synthesis of carbon nanotubes functionalized with iron nanoparticles and coffee husk biomass for efficient removal of losartan and diclofenac: Adsorption kinetics and ANN modeling studies
This study focused on the production of green functionalized carbon nanotubes (CNTs) and using them in the adsorption of the pharmaceuticals Losartan (LOS) and Diclofenac (DIC). The efficiency of the methodology was verified by characterization techniques. Elemental composition analysis indicated a significant increase in the iron content after the green functionalization, proving the effectiveness of the method. Thermogravimetric analysis showed similar thermal degradation profiles for pristine CNTs and functionalized CNTs, indicating better post-functionalization thermal stability. BET analysis revealed mesoporous charac...
Source: Environmental Research - March 23, 2024 Category: Environmental Health Authors: Heloisa P S Costa Emanuele D V Duarte Fl ávio V da Silva Meuris G C da Silva Melissa G A Vieira Source Type: research
Therapeutic potential of ramipril, losartan, and spironolactone against sepsis-associated liver tissue injury induced by cecal ligation and puncture in rats
CONCLUSIONS: Administration of ramipril, losartan, or spironolactone after CLP produced a hepatoprotective effect in rats, possibly by reducing oxidative stress, inflammation, and apoptosis.PMID:38497865 | DOI:10.26355/eurrev_202403_35596 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: A Al-Kadi M El-Daly N F G El-Tahawy O Fahmi A B Abdel-Naim M M A Khalifa A F Ahmed Source Type: research
Therapeutic potential of ramipril, losartan, and spironolactone against sepsis-associated liver tissue injury induced by cecal ligation and puncture in rats
CONCLUSIONS: Administration of ramipril, losartan, or spironolactone after CLP produced a hepatoprotective effect in rats, possibly by reducing oxidative stress, inflammation, and apoptosis.PMID:38497865 | DOI:10.26355/eurrev_202403_35596 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: A Al-Kadi M El-Daly N F G El-Tahawy O Fahmi A B Abdel-Naim M M A Khalifa A F Ahmed Source Type: research
Therapeutic potential of ramipril, losartan, and spironolactone against sepsis-associated liver tissue injury induced by cecal ligation and puncture in rats
CONCLUSIONS: Administration of ramipril, losartan, or spironolactone after CLP produced a hepatoprotective effect in rats, possibly by reducing oxidative stress, inflammation, and apoptosis.PMID:38497865 | DOI:10.26355/eurrev_202403_35596 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: A Al-Kadi M El-Daly N F G El-Tahawy O Fahmi A B Abdel-Naim M M A Khalifa A F Ahmed Source Type: research
Therapeutic potential of ramipril, losartan, and spironolactone against sepsis-associated liver tissue injury induced by cecal ligation and puncture in rats
CONCLUSIONS: Administration of ramipril, losartan, or spironolactone after CLP produced a hepatoprotective effect in rats, possibly by reducing oxidative stress, inflammation, and apoptosis.PMID:38497865 | DOI:10.26355/eurrev_202403_35596 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: A Al-Kadi M El-Daly N F G El-Tahawy O Fahmi A B Abdel-Naim M M A Khalifa A F Ahmed Source Type: research
Therapeutic potential of ramipril, losartan, and spironolactone against sepsis-associated liver tissue injury induced by cecal ligation and puncture in rats
CONCLUSIONS: Administration of ramipril, losartan, or spironolactone after CLP produced a hepatoprotective effect in rats, possibly by reducing oxidative stress, inflammation, and apoptosis.PMID:38497865 | DOI:10.26355/eurrev_202403_35596 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: A Al-Kadi M El-Daly N F G El-Tahawy O Fahmi A B Abdel-Naim M M A Khalifa A F Ahmed Source Type: research
