Positive effect of deep diaphragmatic breathing training on gastroesophageal reflux-induced chronic cough: a clinical randomized controlled study
CONCLUSION: DEP training can improve cough symptoms as an adjunctive treatment in GERC patients.TRIAL REGISTRATION: The protocol was registered in February 2, 2022 via the Chinese Clinical Trials Register ( http://www.chictr.org.cn/ ) [ChiCTR2200056246].PMID:38637797 | PMC:PMC11027235 | DOI:10.1186/s12931-024-02783-5 (Source: Respiratory Care)
Source: Respiratory Care - April 18, 2024 Category: Respiratory Medicine Authors: Shanshan Niu Tongyangzi Zhang Wanzhen Li Siwan Wen Lei Dong Shengyuan Wang Wenbo Shi Cuiqin Shi Yuqin Shen Qianchun Huang Yaling Tan Xianghuai Xu Li Yu Source Type: research

Profile of Patients with Maxillofacial Space Infections and Associated Risk Factors
CONCLUSION: Our study showed that the age of the patient and evidence of bacterial culture were potential predictors of prolonged hospital stay among patients operated for maxillofacial space infections.PMID:38633105 | PMC:PMC11022519 | DOI:10.1155/2024/9304671 (Source: The Scientific World Journal)
Source: The Scientific World Journal - April 18, 2024 Category: Science Authors: Srikanth Gadicherla Kirti Manglani Kalyana C Pentapati Adarsh Kudva Chithra Aramanadka Rajaji Chandravel Source Type: research

Clinical utilization of airway inflammatory biomarkers in the prediction and monitoring of clinical outcomes in patients with chronic obstructive pulmonary disease
Expert Rev Mol Diagn. 2024 Apr 18. doi: 10.1080/14737159.2024.2344777. Online ahead of print.ABSTRACTINTRODUCTION: Chronic obstructive pulmonary disease (COPD) accounts for 545 million people living with chronic respiratory disorders and is the third leading cause of morbidity and mortality around the world. COPD is a progressive disease, characterized by episodes of acute worsening of symptoms such as cough, dyspnea, and sputum production.AREAS COVERED: Airway inflammation is a prominent feature of COPD. Chronic airway inflammation results in airway structural remodeling and emphysema. Persistent airway inflammation is a ...
Source: Expert Review of Molecular Diagnostics - April 18, 2024 Category: Laboratory Medicine Authors: Dina Yehia Clarus Leung Don D Sin Source Type: research

Sputum colour as a simplified effective biomarker for clinical assessment of bronchiectasis
Extract Bronchiectasis is a structural lung disease characterised by chronic airway inflammation due to various aetiologies, with a vicious circle of recurrent infections, chronic inflammation, impaired mucociliary clearance and structural damage that collectively result in clinical progression [1]. The most prominent clinical manifestations of bronchiectasis are chronic cough and mucopurulent sputum production, the consequence of airway mucus hypersecretion and heightened inflammatory responses which could predispose to irreversible airway destruction [2, 3]. Amid this vicious circle of bronchiectasis pathogenesis is chro...
Source: European Respiratory Journal - April 18, 2024 Category: Respiratory Medicine Authors: Tang, R.-d., Yue, J.-q., Guan, W.-j. Tags: Editorials Source Type: research

Early life exposure to pollens and increased risks of childhood asthma: a prospective cohort study in Ontario children
Extract Asthma is a disease characterised by wheeze, cough and shortness of breath, and constitutes the most prevalent chronic disease among children [1]. Various phenotypes have been specifically identified in the paediatric population, and include early transient wheeze, current wheeze/asthma, and mild or moderate asthma [2]. Lifestyle behaviours, genetics, maternal and paternal factors, and environment exposures have been identified as risk factors in the multifactorial aetiology of childhood asthma [3]. (Source: European Respiratory Journal)
Source: European Respiratory Journal - April 18, 2024 Category: Respiratory Medicine Authors: Stanescu, C., Talarico, R., Weichenthal, S., Villeneuve, P. J., Smargiassi, A., Stieb, D. M., To, T., Hebbern, C., Crighton, E., Lavigne, E. Tags: Research Letters Source Type: research

Efficacy of early administration of sacubitril/valsartan after coronary artery revascularization in patients with acute myocardial infarction complicated by moderate-to-severe mitral regurgitation: a randomized controlled trial
AbstractEffects of angiotensin receptor/neprilysin inhibitors (ARNI) on ventricular remodeling in patients with heart failure, especially heart failure with reduced ejection fraction (HFrEF), are better than those of angiotensin-converting enzyme inhibitors (ACEI). Acute myocardial infarction (AMI) complicated by mitral regurgitation exacerbates ventricular remodeling and increases the risk of heart failure. There is limited evidence on the effects of early administration of ARNI in patients with AMI complicated by mitral regurgitation. The aim of this trial was to examine the effectiveness and the safety of early administ...
Source: Heart and Vessels - April 18, 2024 Category: Cardiology Source Type: research

Positive effect of deep diaphragmatic breathing training on gastroesophageal reflux-induced chronic cough: a clinical randomized controlled study
To explore the efficacy of deep diaphragmatic breathing training (DEP) in patients with gastroesophageal reflux-induced chronic cough (GERC). (Source: Respiratory Research)
Source: Respiratory Research - April 18, 2024 Category: Respiratory Medicine Authors: Shanshan Niu, Tongyangzi Zhang, Wanzhen Li, Siwan Wen, Lei Dong, Shengyuan Wang, Wenbo Shi, Cuiqin Shi, Yuqin Shen, Qianchun Huang, Yaling Tan, Xianghuai Xu and Li Yu Tags: Research Source Type: research

Hepatopulmonary syndrome: Case report of the evidence of intrapulmonary shunt on < sup > 99m < /sup > Tc-MAA scintigraphy and contrast transthoracic echocardiography
We report a 57-year-old woman with a history of liver cirrhosis presented with progressive cyanosis, exertional dyspnea and a dry cough. Oxyhemoglobin saturation was 88.5% on room air. Contrast transthoracic echocardiography (cTTE) and technetium-99m-macroaggregated albumin (99mTc-MAA) scintigraphy showed an intrapulmonary shunting and confirmed HPS.PMID:38629817 | DOI:10.1967/s002449912704 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - April 17, 2024 Category: Nuclear Medicine Authors: Pingping Zhou Jun Yang Source Type: research

GSE240646 First exploration of the altered microbial gut-lung axis in the pathogenesis of human refractory chronic cough
Contributors : Matteo Ramazzotti ; Amedeo Amedei ; Simone Baldi ; Leandro Di GloriaSeries Type : OtherOrganism : Homo sapiensv3-v4 16S rRNA sequencing was used to characterize both gut and oral microbiota composition of RCC (refractory chronic cough) patients and matched healthy controls (HC). The groups are matched in age and gender. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - April 17, 2024 Category: Genetics & Stem Cells Tags: Other Homo sapiens Source Type: research

Cancers, Vol. 16, Pages 1534: A Prospective Study on Deep Inspiration Breath Hold Thoracic Radiation Therapy Guided by Bronchoscopically Implanted Electromagnetic Transponders
Conclusions: Bronchoscopically implanted electromagnetic transponder&amp;ndash;guided DIBH lung RT is feasible and safe, allowing for precise tumor targeting and reduced normal tissue exposure. Transponder&amp;ndash;antenna distance was the most common challenge due to a limited antenna range, which could sometimes be circumvented by prone positioning. (Source: Cancers)
Source: Cancers - April 17, 2024 Category: Cancer & Oncology Authors: Yuzhong Jeff Meng Nikhil P. Mankuzhy Mohit Chawla Robert P. Lee Ellen D. Yorke Zhigang Zhang Emily Gelb Seng Boh Lim John J. Cuaron Abraham J. Wu Charles B. Simone Simone II Daphna Y. Gelblum Dale Michael Lovelock Wendy Harris Andreas Rimner Tags: Article Source Type: research

Perinatal exposure to traffic related air pollutants and the risk of infection in the first six months of life: a cohort study from a low-middle income country
ConclusionOur study adds to the evidence that perinatal exposure to fine particles is associated with respiratory tract infection in infants in a low-middle income country. (Source: International Archives of Occupational and Environmental Health)
Source: International Archives of Occupational and Environmental Health - April 17, 2024 Category: Occupational Health Source Type: research

The Association Between Postoperative Persistent Cough and Bronchial Angle
Ann Surg Oncol. 2024 Apr 16. doi: 10.1245/s10434-024-15256-2. Online ahead of print.NO ABSTRACTPMID:38625599 | DOI:10.1245/s10434-024-15256-2 (Source: Ann Oncol)
Source: Ann Oncol - April 16, 2024 Category: Cancer & Oncology Authors: Takashi Ohtsuka Source Type: research

Preparation, structural characteristics and pharmacological activity of polysaccharides from Polygala tenuifolia: A review
Carbohydr Res. 2024 Apr 10;539:109117. doi: 10.1016/j.carres.2024.109117. Online ahead of print.ABSTRACTPolygala tenuifolia is a traditional Chinese medicine with a long history of application, with the efficacy of suppressing cough, calming asthma, tranquilizing the mind, and benefiting the intellect. It is classified as a top-quality medicine in Shennong's Classic of Materia Medica. Polysaccharide is an important active ingredient in Polygala tenuifolia, which consists of several monosaccharides, including Ara, Gal, Glc, and so on. In this review, the preparation methods, structural characteristics, and biological activi...
Source: Carbohydrate Research - April 16, 2024 Category: Genetics & Stem Cells Authors: Yuanyuan Li Huimin Zheng Qiuhui Yao Yongbo Ma Lei Wang Qian Liu Yuhong Liu Source Type: research