Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray
Conditions: Sore Throat; Cough; Hoarseness; Hemodynamic Instability Interventions: Device: MADgic Atomizer; Device: Lignocaine pump spray Sponsors: Universiti Sains Malaysia Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 19, 2024 Category: Research Source Type: clinical trials

Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents
Conditions: Asthma; Asthma in Children; Dyspnea; Cough; Pneumonia; Wheezing; Shortness of Breath; Chest Tightness; Lower Respiratory Tract and Lung Infections; Recurrent Respiratory Tract Infections; Mucus; Plug Sponsors: Charles University, Czech Republic Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials

Retrospective Study of Cough Variant Asthma
Conditions: Asthma Interventions: Diagnostic Test: positive bronchial provocation test Sponsors: The First Affiliated Hospital of Zhejiang Chinese Medical University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials

Does the Coaching Function Improve the Learning of Mechanical In-exsufflation (MI-E) in Paediatric Subjects?
Conditions: Cough; Airway Clearance Impairment; Neuromuscular Diseases Interventions: Other: Learning the use of an in-exsufflation device with the guidance of a physiotherapist; Other: Using the coaching mode Sponsors: Cliniques universitaires Saint-Luc- Universit é Catholique de Louvain Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials

Trevi Therapeutics Announces the Initiation of its Phase 2b CORAL Clinical Trial of Haduvio for Chronic Cough in Idiopathic Pulmonary Fibrosis (IPF)
NEW HAVEN, Conn., Dec. 5, 2023 /PRNewswire/ -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for patients with chronic cough in... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - December 5, 2023 Category: Pharmaceuticals Source Type: clinical trials

Effect Of Cough Assist Device On Hemodynamic Status And Oxygen Saturation For Ventilated Children
Conditions: Pneumonia Childhood; Intensive Care Unit; Children Interventions: Device: Cough assist device Sponsors: Cairo University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 4, 2023 Category: Research Source Type: clinical trials

Trevi Therapeutics Announces the Initiation of its Phase 2a RIVER Clinical Trial of Haduvio ™ for Refractory Chronic Cough
NEW HAVEN, Conn., Nov. 2, 2023 /PRNewswire/ -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for difficult to treat patients with... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - November 2, 2023 Category: Pharmaceuticals Source Type: clinical trials

Alleviation of Common Cold Symptoms
Conditions: Common Cold; Pharyngitis; Fever; Congestion; Rhinorrhea; Cough; Sore-throat; Sore Throats Viral; Malaise; Headache; Runny Nose; Sneezing Interventions: Drug: Wintergreen Throat Spray and Aspirin Tablet; Drug: Aspirin Throat Spray and Placebo Tablet; Dietary Supplement: Wintergreen Throat Spray and Placebo Tablet; Other: Placebo Throat Spray and Placebo Tablet Sponsors: Applied Biological Laboratories Inc; Econometrica, Inc. Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 30, 2023 Category: Research Source Type: clinical trials

Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal Injury
Conditions: Laryngeal Injury; Hoarseness; Cough; Sore-throat; Intubation Complication; Bucking, Anesthesia Related Interventions: Device: Triglotix ®; Device: Conventional endotracheal tube Sponsors: University Hospital of the Nuestra Se ñora de Candelaria Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 30, 2023 Category: Research Source Type: clinical trials

A Multiple-Dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of HS-10383
Conditions: Cough Interventions: Drug: HS-10383; Drug: HS-10383 Placebo Sponsors: Jiangsu Hansoh Pharmaceutical Co., Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 20, 2023 Category: Research Source Type: clinical trials

Trevi Therapeutics Announces Results from Phase 2b/3 PRISM Open-Label Extension Study of Haduvio in Prurigo Nodularis
NEW HAVEN, Conn., Oct. 13, 2023 Trevi Therapeutics, Inc., a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio (oral nalbuphine ER) for difficult to treat patients with chronic cough in idiopathic pulmonary... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - October 14, 2023 Category: Pharmaceuticals Source Type: clinical trials

A Clinical Validation Study to Evaluate the Diagnostic Accuracy of a Cough-based Auxiliary Diagnosis Algorithm for COPD
Conditions: COPD; Cough; Algorithm Sponsors: Ruijin Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 13, 2023 Category: Research Source Type: clinical trials

Assessment of radio(chemo)therapy-related dysphagia in head and neck cancer patients based on cough-related acoustic features: a prospective phase II national clinical trial (ACCOUGH-P/A trial)
This study is expected to develop methods of acoustic cough analysis to enhance the assessment of radiation-associated dysphagia in head and neck cancer patients following (chemo)radiation.Trial registrationInternational Standard Randomized Controlled Trials Number (ISRCTN) registry ISRCTN16540497. Accepted on 23 June 2023. (Source: Trials)
Source: Trials - September 29, 2023 Category: Research Source Type: clinical trials

Bolus vs. Continuous IV Lidocaine Against Post-Extubation Cough in Post-Thyroidectomy Patients
Condition:   Cough Intervention:   Drug: Lidocaine IV Sponsor:   Universitas Padjadjaran Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials