X-ray, MRI show link between steroid injections and worsened arthritis
X-ray and MRI imaging results have shown a link between corticosteroid injection...Read more on AuntMinnie.comRelated Reading: MRI casts doubt on the benefits of taking NSAIDs for arthritis NaF-PET shows bone formation in psoriatic arthritis patients AI challenged to diagnose RA: Task complete PET predicts treatment response in arthritis patients Can cooled RF ablation relieve post-knee replacement pain? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - November 29, 2022 Category: Radiology Source Type: news

Remdesivir reduces COVID-19 mortality in a real-world setting
The COVID-19 pandemic has led to an explosion of clinical research resulting in the development of a variety of vaccines and treatments, although the efficacy of some remains controversial. Now, researchers from Japan report that remdesivir, a drug whose effectiveness has been debated, appears to make a big difference in Japanese patients with COVID-19 who received corticosteroids in the ICU. (Source: World Pharma News)
Source: World Pharma News - November 25, 2022 Category: Pharmaceuticals Tags: Featured Research and Development Source Type: news

Asthma Deterioration Slowed With Combination Inhaler
(MedPage Today) -- LOUISVILLE, Ky. -- An investigational fixed-dose combination of a short-acting beta2-adrenergic agonist and an inhaled corticosteroid appeared to slow the deterioration in lung function and reduce severe exacerbations for patients... (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - November 14, 2022 Category: Allergy & Immunology Source Type: news

ANCA-Associated Vasculitis: Novel Biologic Shows Promise for Replacing Steroids
(MedPage Today) -- PHILADELPHIA -- An investigational monoclonal antibody targeting C5a complement, when partially or fully substituted for corticosteroids, appeared to help patients with ANCA-associated vasculitis (AAV) avoid some of the side... (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - November 13, 2022 Category: Endocrinology Source Type: news

Corticosteroid Use and Incidence of VAP in COVID-19 Patients Corticosteroid Use and Incidence of VAP in COVID-19 Patients
Are corticosteroid-treated COVID-19 patients at a greater risk for developing ventilator-associated pneumonia? A new study looks at the possible association.Critical Care (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 11, 2022 Category: Consumer Health News Tags: Critical Care Journal Article Source Type: news

Novel Combination Inhaler for Asthma Heads to FDA Panel
(MedPage Today) -- The FDA's Pulmonary-Allergy Drugs Advisory Committee on Tuesday will consider whether a novel two-drug combination inhaler for asthma should be the first FDA-approved product containing an inhaled corticosteroid (budesonide... (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - November 8, 2022 Category: Allergy & Immunology Source Type: news

Janssen to Highlight Latest Scientific Advances in Hematologic Diseases at ASH 2022 with Clinical and Real-World Data Across Innovative Pipeline and Distinguished Portfolio
RARITAN, N.J., November 3, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson are committed to redefining treatment outcomes in the hematology setting and today announced that abstracts from more than 50 company-sponsored studies, plus more than 20 investigator-initiated studies, will be presented at the American Society of Hematology (ASH) Annual Meeting in New Orleans from December 10-13, 2022. Janssen’s commitment to advancing an innovative portfolio of therapies for healthcare professionals and patients is evidenced through more than 70 presentations that span clinical studies and r...
Source: Johnson and Johnson - November 3, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

New Research Focuses on Mesothelioma Brain Metastasis
Distant metastasis is common with malignant pleural mesothelioma – more than 60% of patients experience it – but rarely is it found around the brain. A new study by a team of radiation oncologists in Great Britain, however, suggests that physicians should increase their focus on potential cerebral metastasis in mesothelioma patients. “Patients will continue to live longer as a consequence of newer, more advanced treatments,” the study authors wrote. “It is critical now to recognize mesothelioma’s metastatic potential, particularly cerebral metastasis, which was previously only an autopsy finding.” T...
Source: Asbestos and Mesothelioma News - November 3, 2022 Category: Environmental Health Authors: Fran Mannino Tags: Clinical Trials/Research/Emerging Treatments Pleural Source Type: news

Roche to present data at ASH 2022 showcasing strength of haematology portfolio and expanding into new areas to address more patient needs
Interim data from phase III HAVEN 7 study reinforceHemlibra ’s efficacy and safety in infants with severehaemophilia A without factor VIII inhibitors1New and updated data support use ofPolivy in diffuse large B-cell lymphoma, including its potential as a treatment option for previously untreated patients2New and updated data for innovative CD20xCD3 T-cell engaging bispecific antibodiesLunsumio andglofitamab further enhance their potential as effective, off-the-shelf, fixed-duration treatment options for people with lymphoma3,4,5,6,7First phase III data forcrovalimab show the co-primary efficacy endpoints were met, with s...
Source: Roche Media News - November 3, 2022 Category: Pharmaceuticals Source Type: news

Roche to present data at ASH 2022 showcasing strength of haematology portfolio and expanding into new areas to address more patient needs
Interim data from phase III HAVEN 7 study reinforceHemlibra ’s efficacy and safety in infants with severehaemophilia A without factor VIII inhibitors1New and updated data support use ofPolivy in diffuse large B-cell lymphoma, including its potential as a treatment option for previously untreated patients2New and updated data for innovative CD20xCD3 T-cell engaging bispecific antibodiesLunsumio andglofitamab further enhance their potential as effective, off-the-shelf, fixed-duration treatment options for people with lymphoma3,4,5,6,7First phase III data forcrovalimab show the co-primary efficacy endpoints were met, with s...
Source: Roche Investor Update - November 3, 2022 Category: Pharmaceuticals Source Type: news

Salvat Laboratories announces submission of New Drug Application to the U.S. FDA for Clobetasol Nanoemulsion for treating inflammation and pain after ocular surgery
Salvat Laboratories announced that it has submitted a New Drug Application (NDA) to the FDA for the approval of the first ocular corticosteroid formulated in a nanoemulsion for inflammation and pain in post-ocular surgery patients. This submission comes after two successful phase III clinical trials conducted between 2020 and 2021. (Source: World Pharma News)
Source: World Pharma News - November 2, 2022 Category: Pharmaceuticals Tags: Featured Business Business and Industry Source Type: news

New TREMFYA ® (guselkumab) Data Show an Overall Clinical Response Rate of Approximately 80 Percent in a Phase 2b Induction Study of Adults with Moderately to Severely Active Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 24, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the Phase 2b QUASAR Induction Study 1 in adults with moderately to severely active ulcerative colitis (UC) with inadequate responses to previous treatments. The data presented at the 2022 American College of Gastroenterology (ACG) Annual Scientific Meeting show an overall clinical response rate of approximately 80 percent in patients who were randomized to TREMFYA® (guselkumab).Clinical responsea at weeks 12 or 24 of the study was ultimately achieved by 80.2 percent of patients who w...
Source: Johnson and Johnson - October 24, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

What to Know About Severe Asthma in Kids
Asthma isn’t always a quick and easy diagnosis in children. According to a 2014 task force assembled by the American Thoracic Society and the European Respiratory Society, pediatric severe asthma can be diagnosed if a child’s symptoms require treatment with high-dose inhaled corticosteroids plus a second “controller” medication for a full year, and/or systemic corticosteroids for half a year or longer. In other words, its diagnostic criteria are based on the intractability of its symptoms. “It’s definitely a limitation when you’re defining a disease state based on how much medicine...
Source: TIME: Health - October 21, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized Disease healthscienceclimate Source Type: news

Suffering from Seasonal Allergies? Here ’ s What Experts Say Works Best
Millions of Americans spend weeks each year sneezing and sniffling due to allergies to seasonal triggers such as tree, grass, or ragweed pollen. And for the subset of people who are allergic to year-round household irritants like dust mites, mold, and cockroaches, any season can turn into allergy season. Allergy symptoms happen when your immune system interprets what should be a relatively benign substance as a threat. The severity of symptoms and the difficulty of treating them can vary depending on your genes, how many substances you’re allergic to, and your level of exposure, says Dr. H. James Wedner, an allergy a...
Source: TIME: Health - October 21, 2022 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthscienceclimate medicine Source Type: news

Topical Dermatologic Corticosteroids: In Vivo Bioequivalence
Topical Dermatologic Corticosteroids: In Vivo Bioequivalence (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 21, 2022 Category: Drugs & Pharmacology Authors: FDA Source Type: news