Total testosterone cut-off value indicating androgen-secreting tumor in premenopausal women with hirsutism
CONCLUSIONS: At the TT level, a two-fold increase CULN in FIPH indicates an ASTM source. In addition, ASR after LDDST is a useful parameter in the exclusion of ASTM sources in the same patient population.PMID:37782181 | DOI:10.26355/eurrev_202309_33791 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - October 2, 2023 Category: Drugs & Pharmacology Authors: M G üneş E G üneş F Öztürk Source Type: research

Total testosterone cut-off value indicating androgen-secreting tumor in premenopausal women with hirsutism
CONCLUSIONS: At the TT level, a two-fold increase CULN in FIPH indicates an ASTM source. In addition, ASR after LDDST is a useful parameter in the exclusion of ASTM sources in the same patient population.PMID:37782181 | DOI:10.26355/eurrev_202309_33791 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - October 2, 2023 Category: Drugs & Pharmacology Authors: M G üneş E G üneş F Öztürk Source Type: research

Total testosterone cut-off value indicating androgen-secreting tumor in premenopausal women with hirsutism
CONCLUSIONS: At the TT level, a two-fold increase CULN in FIPH indicates an ASTM source. In addition, ASR after LDDST is a useful parameter in the exclusion of ASTM sources in the same patient population.PMID:37782181 | DOI:10.26355/eurrev_202309_33791 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - October 2, 2023 Category: Drugs & Pharmacology Authors: M G üneş E G üneş F Öztürk Source Type: research

The use of liquid chromatography-tandem mass spectrometry in newborn screening for congenital adrenal hyperplasia: improvements and future perspectives
Newborn screening for congenital adrenal hyperplasia using 17-hydroxyprogesterone by immunoassay remains controversial despite screening been available for almost 40 years. Screening is confounded by poor immunoassay specificity, fetal adrenal physiology, stress, and illness which can result in a large number of false positive screening tests. Screening programmes apply higher screening thresholds based on co-variates such as birthweight or gestational age but the false positive rate using immunoassay remains high. Mass spectrometry was first applied to newborn screening for congenital adrenal hyperplasia over 15 years ago...
Source: Frontiers in Endocrinology - October 2, 2023 Category: Endocrinology Source Type: research

Corrigendum: Getting pregnant with congenital adrenal hyperplasia: assisted reproduction and pregnancy complications. A systematic review and meta-analysis
(Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - September 28, 2023 Category: Endocrinology Source Type: research

Erratum: Getting pregnant with congenital adrenal hyperplasia: assisted reproduction and pregnancy complications. A systematic review and meta-analysis
(Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - September 28, 2023 Category: Endocrinology Source Type: research

Genotype-Specific Cortisol Reserve in a Cohort of Subjects with Non-Classic Congenital Adrenal Hyperplasia (NCCAH)
CONCLUSION: The high rate of partial adrenal insufficiency in the mild/severe group underscores the need to carefully consider the value of glucocorticoid therapy cessation and the importance of stress coverage in this group.PMID:37715965 | DOI:10.1210/clinem/dgad546 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - September 16, 2023 Category: Endocrinology Authors: Ilana Koren Naomi Weintrob Rebekka Kebesch Hussein Majdoub Nili Stein Shulamit Naor Anat Segev-Becker Source Type: research

Genotype-Specific Cortisol Reserve in a Cohort of Subjects with Non-Classic Congenital Adrenal Hyperplasia (NCCAH)
CONCLUSION: The high rate of partial adrenal insufficiency in the mild/severe group underscores the need to carefully consider the value of glucocorticoid therapy cessation and the importance of stress coverage in this group.PMID:37715965 | DOI:10.1210/clinem/dgad546 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - September 16, 2023 Category: Endocrinology Authors: Ilana Koren Naomi Weintrob Rebekka Kebesch Hussein Majdoub Nili Stein Shulamit Naor Anat Segev-Becker Source Type: research