The effect of Rosa canina L. and a polyherbal formulation syrup in patients with attention-deficit/hyperactivity disorder: a study protocol for a multicenter randomized controlled trial
This study aims to determine the efficacy and safety of two herbal medicine products, includingRosa canina L. (RC) and a polyherbal formulation (PHF) syrup, on the clinical manifestations of ADHD in children and adolescents.MethodsNinety ADHD patients based on DSM-5 diagnostic criteria will be randomly assigned equally into three groups: (1) RC syrup + methylphenidate (MP), (2) PHF syrup + MP, and (3) placebo + MP according to the inclusion criteria (30 subjects in each group). The syrup dosage is 5cc every 8 h, and MP will have a stabilized dose for 8 weeks during the study. Moreover, Conner’s questionnaires will be com...
Source: Trials - May 23, 2022 Category: Research Source Type: clinical trials

The Role of Brain Dopamine in Chronic Pain
Condition:   Chronic Pain Interventions:   Drug: Methylphenidate;   Drug: carbidopa-levodopa;   Drug: Placebo Sponsor:   University of Rochester Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 17, 2022 Category: Research Source Type: clinical trials