Molecules, Vol. 28, Pages 6171: LC-MS/MS Evaluation of Pyrrolizidine Alkaloids Profile in Relation to Safety of Comfrey Roots and Leaves from Polish Sources
aranowska
Comfrey (Symphytum officinale L.) has a long tradition of use in the treatment of musculoskeletal disorders. However, due to hepatotoxic pyrrolizidine alkaloids (PAs), the EMA restricts the use of comfrey root (CR) to external use only and for short periods of time. Recent studies indicate a low permeability of PAs across the skin, calling into question the safety of topical application of products containing comfrey preparations. The aim of our work was to develop and validate an HPLC method enabling the separation of isomeric PAs from comfrey and, on this basis, to assess the potential toxicity of CR and co...
Source: Molecules - August 21, 2023 Category: Chemistry Authors: Katarzyna Kimel Sylwia Godlewska Micha ł Gleńsk Katarzyna Gobis Justyna O śko Ma łgorzata Grembecka Miros ława Krauze-Baranowska Tags: Article Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Concept for integrative pain treatment of osteoarthritis of the knee based on the evidence for conservative and complementary therapies
CONCLUSION: Complementary treatment approaches, such as acupuncture, tai chi/qigong, topical naturopathic self-treatment and leeches (with limitations) can, in addition to behavioral changes, exercise therapy and short-term pharmacological treatment, be important evidence-based components of integrative pain management concepts, e.g. in terms of an interdisciplinary multimodal pain treatment (IMPT). Besides pain reduction and functional improvement they promote the internal control conviction through the possibility of self-treatment and self-exercise.PMID:37505229 | DOI:10.1007/s00482-023-00739-0 (Source: Schmerz)
Source: Schmerz - July 28, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Source Type: research
Phytotherapy in paediatric skin disorders- a systematic literature review
CONCLUSIONS: Based on the application of the Jadad score, eight out of 17 of the studies examined were of low quality. Yet we found some indication that evening primrose oil may be effective for treating atopic dermatitis in children, while comfrey appears to have a positive effect on wound healing. Interestingly, none of the studies found positive effects for treating skin disorders with aloe vera or chamomile.PMID:36958415 | DOI:10.1016/j.ctim.2023.102942 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 23, 2023 Category: Complementary Medicine Authors: Evelyne Kloter Fiorella Albanese Reka Schweighoffer Ursula Wolf Source Type: research
Phytotherapy in paediatric skin disorders- a systematic literature review
CONCLUSIONS: Based on the application of the Jadad score, eight out of 17 of the studies examined were of low quality. Yet we found some indication that evening primrose oil may be effective for treating atopic dermatitis in children, while comfrey appears to have a positive effect on wound healing. Interestingly, none of the studies found positive effects for treating skin disorders with aloe vera or chamomile.PMID:36958415 | DOI:10.1016/j.ctim.2023.102942 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 23, 2023 Category: Complementary Medicine Authors: Evelyne Kloter Fiorella Albanese Reka Schweighoffer Ursula Wolf Source Type: research
Phytotherapy in paediatric skin disorders - A systematic literature review
CONCLUSIONS: Based on the application of the Jadad score, eight out of 17 of the studies examined were of low quality. Yet we found some indication that evening primrose oil may be effective for treating atopic dermatitis in children, while comfrey appears to have a positive effect on wound healing. Interestingly, none of the studies found positive effects for treating skin disorders with aloe vera or chamomile.PMID:36958415 | DOI:10.1016/j.ctim.2023.102942 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 23, 2023 Category: Complementary Medicine Authors: Evelyne Kloter Fiorella Albanese Reka Schweighoffer Ursula Wolf Source Type: research
Phytotherapy in paediatric skin disorders - A systematic literature review
CONCLUSIONS: Based on the application of the Jadad score, eight out of 17 of the studies examined were of low quality. Yet we found some indication that evening primrose oil may be effective for treating atopic dermatitis in children, while comfrey appears to have a positive effect on wound healing. Interestingly, none of the studies found positive effects for treating skin disorders with aloe vera or chamomile.PMID:36958415 | DOI:10.1016/j.ctim.2023.102942 (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - March 23, 2023 Category: Complementary Medicine Authors: Evelyne Kloter Fiorella Albanese Reka Schweighoffer Ursula Wolf Source Type: research
