5-ASA-intolerance and Increased Risk of Colectomy for UC 5-ASA-intolerance and Increased Risk of Colectomy for UC
5-aminosalicylate is first-line therapy in ulcerative colitis, but some patients cannot tolerate its side effects. Are these patients at higher risk of colectomy?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 20, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Key Studies in Ulcerative Colitis From ACG 2020 Virtual Key Studies in Ulcerative Colitis From ACG 2020 Virtual
Highlights in ulcerative colitis from the ACG 2020 virtual meeting include the OCTAVE tofacitinib trial program, the long-term and comparative efficacy of vedolizumab, and long-term colectomy trends.Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 18, 2020 Category: Consumer Health News Tags: None ReCAP Source Type: news

Fulminant C diff Debate: Fecal Transplants or Antibiotics? Fulminant C diff Debate: Fecal Transplants or Antibiotics?
One expert at IDWeek says fecal microbiota transplants should be initiated before colectomy. Another says traditional therapeutics are still the best choice as not enough is known about FMT.Medscape Medical News (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - October 28, 2020 Category: Surgery Tags: Gastroenterology News Source Type: news

Roche provides update on phase III studies of etrolizumab in people with moderately to severely active ulcerative colitis
Basel, 10 August 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced topline results from its phase III study programme evaluating the investigational medicine etrolizumab in people with moderately to severely active ulcerative colitis. Mixed results were seen in studies evaluating etrolizumab as an induction therapy, and both studies evaluating etrolizumab as a maintenance therapy failed to meet their primary endpoints, showing no significant difference in the proportion of people achieving remission with subcutaneous etrolizumab versus placebo. In the HIBISCUS I induction study, in people without prior anti-tumour ...
Source: Roche Media News - August 10, 2020 Category: Pharmaceuticals Source Type: news

Roche provides update on phase III studies of etrolizumab in people with moderately to severely active ulcerative colitis
Basel, 10 August 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced topline results from its phase III study programme evaluating the investigational medicine etrolizumab in people with moderately to severely active ulcerative colitis. Mixed results were seen in studies evaluating etrolizumab as an induction therapy, and both studies evaluating etrolizumab as a maintenance therapy failed to meet their primary endpoints, showing no significant difference in the proportion of people achieving remission with subcutaneous etrolizumab versus placebo. In the HIBISCUS I induction study, in people without prior anti-tumour ...
Source: Roche Investor Update - August 10, 2020 Category: Pharmaceuticals Source Type: news

Early Colectomy for Toxic Megacolon in C. difficile Infection Early Colectomy for Toxic Megacolon in C. difficile Infection
Can early colectomy in patients who have toxic megacolon due to Clostridium difficile colitis improve outcomes and reduce mortality?Southern Medical Journal (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - August 4, 2020 Category: Surgery Tags: General Surgery Journal Article Source Type: news

What Is Laparoscopic Left Colectomy/Hemicolectomy?
Title: What Is Laparoscopic Left Colectomy/Hemicolectomy?Category: Procedures and TestsCreated: 7/10/2020 12:00:00 AMLast Editorial Review: 7/10/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 10, 2020 Category: Nutrition Source Type: news

What Is Laparoscopic Right Colectomy?
Title: What Is Laparoscopic Right Colectomy?Category: Procedures and TestsCreated: 7/9/2020 12:00:00 AMLast Editorial Review: 7/9/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 9, 2020 Category: Nutrition Source Type: news

Potential for Prognostic Biomarkers in T1 Colorectal Cancer Treatment Selection
In this study, researchers found that endoscopic therapy was the most effective strategy for patients with T1 CRC with less aggressive biomarker profiles and laparoscopic colectomy was the most effective for patients with more aggressive profiles. (Source: CancerNetwork)
Source: CancerNetwork - March 23, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Biologics May Have Changed the Natural History of Ulcerative Colitis Biologics May Have Changed the Natural History of Ulcerative Colitis
The rate of colectomy within the first year after hospital admission for ulcerative colitis has declined in the modern era of biologics, suggesting the advent of biologic therapy has changed the natural history of the disease, researchers report.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - January 30, 2020 Category: Surgery Tags: Gastroenterology News Source Type: news

Robotic Colectomy Safe but Expensive Robotic Colectomy Safe but Expensive
Robotic colectomy appears to be only minimally safer than open colectomy (but not laparoscopic colectomy) and is more costly than the other two alternatives, but its use continues to increase, according to new research.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - November 7, 2019 Category: Surgery Tags: General Surgery News Source Type: news

Bowel Preparation Does Not Reduce Morbidity of Elective Colectomy Bowel Preparation Does Not Reduce Morbidity of Elective Colectomy
Mechanical and oral antibiotic bowel preparation (MOABP) does not reduce surgical site infections (SSIs) or overall morbidity after elective colectomy, compared with no bowel preparation, according to results from the MOBILE trial.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - August 20, 2019 Category: Surgery Tags: General Surgery News Source Type: news

Mechanical, Oral Antibiotic Bowel Prep Yields No Benefit for Colectomy
MONDAY, Aug. 19, 2019 -- Mechanical and oral antibiotic bowel preparation (MOABP) does not reduce surgical site infections (SSIs) or the overall morbidity of colon surgery versus no bowel preparation (NBP), according to a study published online Aug.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 19, 2019 Category: Pharmaceuticals Source Type: news

Diverting Loop Ileostomy Increasingly Used to Manage Fulminant C Difficile Colitis Diverting Loop Ileostomy Increasingly Used to Manage Fulminant C Difficile Colitis
Diverting loop ileostomy (LI) is increasingly favored over total abdominal colectomy (TAC) for the surgical management of patients with fulminant Clostridium difficile colitis, according to a new study.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - July 13, 2019 Category: Surgery Tags: Gastroenterology News Source Type: news

Infliximab Introduction Has Not Cut IBD-Related Hospitalizations
FRIDAY, June 14, 2019 -- Marketplace introduction of infliximab has not resulted in reductions in the population rates of inflammatory bowel disease (IBD)-related hospitalizations or intestinal resections or colectomies, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 14, 2019 Category: Pharmaceuticals Source Type: news